Publications by Aurélien Bornet

Micromolar Concentration Affinity Study on a Benchtop NMR Spectrometer with Secondary 13C Labeled Hyperpolarized Ligands

Benchtop NMR is becoming an increasingly important tool, sometimes providing a simple and low-cost alternative to high-field NMR. The Achilles heel of NMR and even more critically of benchtop NMR is its limited sensitivity. However, when combined with hype ...

AMER CHEMICAL SOC2025

Metal Doping of Strongly Confined Halide Perovskite Nanocrystals under Ambient Conditions

Aurélien Bornet, Emad Oveisi, Pascal Alexander Schouwink

Halide perovskite nanocrystals are promising materials for optoelectronic applications. Metal doping provides an avenue to boost their performance further, e.g., by enhancing light emission, or to provide additional functionalities, such as nanoscale magne ...

American Chemical Society (ACS)2025

Operando Monitoring of Delignification Processes Using 2D 1H-13C HSQC NMR

Jeremy Luterbacher, Aurélien Bornet, Songlan Sun

American Chemical Society (ACS)2025

New melphalan derivatives for the treatment of retinoblastoma in combination with thermotherapy

Paul Joseph Dyson, Aurélien Bornet, Daniel Ortiz Trujillo, Farzaneh Fadaei Tirani

Of the different modalities used to treat retinoblastoma, a chemothermotherapeutic regimen combining carboplatin and thermotherapy (also termed focal therapy), and the application of melphalan as a monotherapy, are particularly successful. Some studies ind ...

Royal Soc Chemistry2024

Controlling Tin Halide Perovskite Oxidation Dynamics in Solution for Perovskite Optoelectronic Devices

Mohammad Khaja Nazeeruddin, Paul Joseph Dyson, Zhaofu Fei, Aurélien Bornet, Roland Christopher Turnell-Ritson, Guixiang Li

As a leading contender to replace lead halide perovskites, tin-based perovskites have demonstrated ever increasing performance in solar cells and light-emitting diodes (LEDs). They tend to be processed with dimethyl sulfoxide (DMSO) solvent, which has been ...

Wiley-VCH Verlag GmbH2024

Inhibition of influenza virus infection in mice by pulmonary administration of a spray dried antiviral drug

Aurélien Bornet, Francesco Stellacci, Paulo Henrique Jacob Silva

Increasing resistance to antiviral drugs approved for the treatment of influenza urges the development of novel compounds. Ideally, this should be complemented by a careful consideration of the administration route. 6′siallyllactosamine-functionalized β-cy ...

2024

Nonclassical Nucleation and Crystallization of LiNbO3 Nanoparticles from the Aqueous Solvothermal Alkoxide Route

Sandrine Gerber, Aurélien Bornet, Adrian Stefan Gheata

The exact molecular reaction pathway and crystallization mechanisms of LiNbO3 nanoparticles under solvothermal conditions are derived through extensive time- and temperature-resolved experiments allowing to track all the transient molecular and solid speci ...

Wiley-V C H Verlag Gmbh2023

Ligand Locking on Quantum Dot Surfaces via a Mild Reactive Surface Treatment

Aurélien Bornet, Raffaella Buonsanti, Anna Loiudice, Ona Segura Lecina

At the outermost surface of colloidal QDs are organic surface ligands which dynamically bind and release in solution to control the growth kinetics, control the size/shape of the crystals, passivate surface states, and provide colloidal stability through f ...

2021

An automated system for fast transfer and injection of hyperpolarized solutions

Aurélien Bornet, Jonas Milani

Dissolution dynamic nuclear polarization (dDNP) has become a hyperpolarization method of choice for enhancing nuclear magnetic resonance (NMR) signals. Nuclear spins are polarized in solid frozen samples (in a so-called polarizer) that are subsequently dis ...

Elsevier2021

Crowding reveals fundamental differences in local vs. global processing in humans and machines

Michael Herzog, Aurélien Bornet, Adrien Christophe Doerig, Oh-Hyeon Choung

Feedforward Convolutional Neural Networks (ffCNNs) have become state-of-the-art models both in computer vision and neuroscience. However, human-like performance of ffCNNs does not necessarily imply human-like computations. Previous studies have suggested t ...

2020

Cross-Reactive Alginate Derivatives for the Production of Dual Ionic−Covalent Hydrogel Microspheres Presenting Tunable Properties for Cell Microencapsulation

Sandrine Gerber, Aurélien Bornet, François Rémi Pierre Noverraz, Luca Szabó

The production of hydrogel micropsheres (MS) presenting physical, mechanical, and biological properties which can be modulated by their chemical composition is required to enlarge the panel of biomaterials for cell transplantation therapies. Functionalizat ...

2019

A cryogen-consumption-free system for dynamic nuclear polarization at 9.4 T

Sami Jannin, Aurélien Bornet, Basile Vuichoud, Mathieu Baudin

Academic Press Inc - Elsevier Science2018

Overhauser effects in non-conducting solids at 1.2 K

Sami Jannin, Aurélien Bornet, Basile Vuichoud, Marc Anthony Caporini, Xiaobin Ji

Academic Press Inc - Elsevier Science2018

Tailored Microstructured Hyperpolarizing Matrices for Optimal Magnetic Resonance Imaging

Sami Jannin, Aurélien Bornet, Basile Vuichoud, Mathieu Baudin

Wiley-VCH Verlag GmbH2018

Dynamic Nuclear Polarization of Long-Lived Nuclear Spin States in Methyl Groups

Geoffrey Bodenhausen, Sami Jannin, Aurélien Bornet, Basile Vuichoud, Daniele Mammoli, Arthur César Pinon, Gabriele Stevanato

We have induced hyperpolarized long-lived states in compounds containing C-13-bearing methyl groups by dynamic nuclear polarization (DNP) at cryogenic temperatures, followed by dissolution with a warm solvent. The hyper polarized methyl long-lived states g ...

Amer Chemical Soc2017

Transportable hyperpolarized metabolites

Geoffrey Bodenhausen, Sami Jannin, Aurélien Bornet, Jonas Milani, Basile Vuichoud, David Benjamin Roger Antoine Gajan, Xiao Ji, David Lyndon Emsley, Aaron James Rossini

Nuclear spin hyperpolarization of C-13-labelled metabolites by dissolution dynamic nuclear polarization can enhance the NMR signals of metabolites by several orders of magnitude, which has enabled in vivo metabolic imaging by MRI. However, because of the s ...

Nature Publishing Group2017

Phenylazide Hybrid-Silica - Polarization Platform for Dynamic Nuclear Polarization at Cryogenic Temperatures

Geoffrey Bodenhausen, Sami Jannin, Aurélien Bornet, Jonas Milani, Basile Vuichoud, David Benjamin Roger Antoine Gajan, David Baudouin

Hyperpolarization of NMR-active nuclei is key to gather high quality spectra of rare species and insensitive isotopes. We have recently established that silica-based materials containing regularly distributed nitroxyl radicals connected to the silica matri ...

Wiley-V C H Verlag Gmbh2017

Hyperpolarization of nitrogen-15 nuclei by cross polarization and dissolution dynamic nuclear polarization

Geoffrey Bodenhausen, Sami Jannin, Aurélien Bornet, Jonas Milani, Basile Vuichoud

Dynamic Nuclear Polarization (DNP) is often achieved by the direct transfer of polarization from electrons to nuclei such as C-13, induced by microwave saturation of the wings of narrow EPR lines of radicals like trityl. In the indirect approach on the oth ...

Amer Inst Physics2017

Structured and porous materials particularly suitable as polarizing agents in dissolution dynamic nuclear polarization

Geoffrey Bodenhausen, Sami Jannin, Aurélien Bornet, David Benjamin Roger Antoine Gajan, David Lyndon Emsley, David Baudouin

The present invention concerns materials consisting in a porous and structured network, this network being at least in part formed by Si atoms, or Si atoms and metal atoms, linked to each other by oxy bridges, comprising organic molecules which include at ...

2016

Highly Repeatable Dissolution Dynamic Nuclear Polarization for Heteronuclear NMR Metabolomics

Geoffrey Bodenhausen, Sami Jannin, Aurélien Bornet, Jonas Milani, Basile Vuichoud, Xiao Ji

At natural C-13 abundance, metabolomics based on heteronuclear NMR is limited by sensitivity. We have recently demonstrated how hyperpolarization by dissolution dynamic nuclear polarization (D-DNP) assisted by cross-polarization (CP) provides a reliable wa ...

Amer Chemical Soc2016