Publications by Rizlan Bernier-Latmani

Speciation-dependent molecular mechanism of electron transfer from the c-type cytochrome MtrC to U(VI)-ligand complexes

Rizlan Bernier-Latmani, Luciano Andres Abriata, Karin Lederballe Meibom, Margaux Camille Andréa Molinas

Members of the Shewanella genus transfer electrons to metal and actinide electron acceptors such as hexavalent uranium, U(VI), via c-type cytochromes. The intracellular mechanism of electron transfer is well studied but the delivery of electrons to externa ...

2025

Biosensor-aided isolation of anaerobic arsenic-methylating bacteria from soil

Rizlan Bernier-Latmani, Karin Lederballe Meibom, Hugo Sallet, Nicolas Louis Maurice Jacquemin

Microbial methylation of arsenic impacts both the toxicity and fate of this environmental contaminant, and is an important component of its biogeochemical cycle. This transformation occurs in flooded paddy fields where soil microorganisms can produce dimet ...

Oxford University Press2025

High-throughput cultivation and isolation of environmental anaerobes using selectively permeable hydrogel capsules

Rizlan Bernier-Latmani, Karin Lederballe Meibom, Hugo Sallet, Nicolas Louis Maurice Jacquemin

Over the past two decades, metagenomics has greatly expanded our understanding of microbial phylogenetic and metabolic diversity. However, most microbial taxa remain uncultured, hindering research and biotechnological applications. Isolating environmental ...

Oxford University Press (OUP)2025

Bile acid 7α-dehydroxylating bacteria accelerate injury-induced mucosal healing in the colon

Rizlan Bernier-Latmani, Kristina Schoonjans, Alessia Perino, Hadrien Charles Edouard Demagny, Eduard Vico Oton, Colin Volet, Antoine Jalil

Host-microbiome communication is frequently perturbed in gut pathologies due to microbiome dysbiosis, leading to altered production of bacterial metabolites. Among these, 7 alpha-dehydroxylated bile acids are notably diminished in inflammatory bowel diseas ...

SPRINGERNATURE2025

The isotopic signature of U(V) during bacterial reduction

Marinella Mazzanti, Rizlan Bernier-Latmani, Radmila Faizova, Margaux Camille Andréa Molinas, Ashley Richards Brown

The two-step electron transfer during bacterial reduction of UVI to UIV is typically accompanied by mass-independent fractionation of the 238U and 235U isotopes, whereby the heavy isotope accumulates in the reduced product. However, the role of the UV inte ...

2024

Reducing conditions influence U(IV) accumulation in sediments during in-situ bioremediation

Vincent Noel, Elena Suvorova Buffat, Rizlan Bernier-Latmani, Daniel Scott Alessi

2024

Growth substrate limitation enhances anaerobic arsenic methylation by Paraclostridium bifermentans strain EML

Rizlan Bernier-Latmani, Karin Lederballe Meibom, Hugo Sallet, Jiangtao Qiao

Microbial arsenic methylation is established as a detoxification process under aerobic conditions (converting arsenite to monomethylated arsenate) but is proposed to be a microbial warfare strategy under anoxic conditions due to the toxicity of its main pr ...

American Society for Microbiology2024

BaiJ and BaiB are key enzymes in the chenodeoxycholic acid 7a-dehydroxylation pathway in the gut microbe Clostridium scindens ATCC 35704

Rizlan Bernier-Latmani, Laure Menin, Karin Lederballe Meibom, Solenne Anne Marie Marion, Théo Nass, Eduard Vico Oton, Colin Volet

Bile acid transformation is a common gut microbiome activity that produces secondary bile acids, some of which are important for human health. One such process, 7α-dehydroxylation, converts the primary bile acids, cholic acid and chenodeoxycholic acid, to ...

2024

Strain-dependent induction of primary bile acid 7-dehydroxylation by cholic acid

Rizlan Bernier-Latmani, Karin Lederballe Meibom, Nicolas Louis Maurice Jacquemin, Eduard Vico Oton, Colin Volet

Springer Science and Business Media LLC2024

Pentavalent U reactivity impacts U isotopic fractionation during reduction by magnetite

Rizlan Bernier-Latmani, Barbora Bártová, Luca Loreggian, Zezhen Pan

Meaningful interpretation of U isotope measurements relies on unraveling the impact of reduction mechanisms on the isotopic fractionation. Here, the isotope fractionation of hexavalent U [U(VI)] was investigated during its reductive mineralization by magne ...

2024

WP15 ConCorD state-of-the-art report (container corrosion under disposal conditions)

Rizlan Bernier-Latmani

A sealed container for the geological disposal of spent nuclear fuel and vitrified high-level waste is the only component of a deep geological repository that provides complete containment of radionuclides. As such, attention is focused on its lifetime. Th ...

Frontiers Media SA2024

Microbial hydrogen sinks in the sand-bentonite backfill material for the deep geological disposal of radioactive waste

Rizlan Bernier-Latmani, Manon Frutschi, Niels Burzan, Aislinn Ann Boylan, Nicolas Louis Maurice Jacquemin, Simiao Wang, Camille Aude Rolland

The activity of subsurface microorganisms can be harnessed for engineering projects. For instance, the Swiss radioactive waste repository design can take advantage of indigenous microorganisms to tackle the issue of a hydrogen gas (H2) phase pressure build ...

Frontiers Media SA2024

Electron flux is a key determinant of uranium isotope fractionation during bacterial reduction

Rizlan Bernier-Latmani, Margaux Camille Andréa Molinas, Ashley Richards Brown

Uranium isotopic signatures in the rock record are utilized as a proxy for past redox conditions on Earth. However, these signatures display significant variability that complicates the interpretation of specific redox conditions. Using the model uranium-r ...

2023

Mechanism of Reduction of Aqueous U(V)-dpaea and Solid-Phase U(VI)-dpaea Complexes: The Role of Multiheme c-Type Cytochromes

Marinella Mazzanti, Rizlan Bernier-Latmani, Karin Lederballe Meibom, Radmila Faizova, Margaux Camille Andréa Molinas

The biological reduction of soluble U(VI) complexes to form immobile U(IV) species has been proposed to remediate contaminated sites. It is well established that multiheme c-type cytochromes (MHCs) are key mediators of electron transfer to aqueous phase U( ...

2023

Spatially Explicit Linkages Between Redox Potential Cycles and Soil Moisture Fluctuations

Rizlan Bernier-Latmani, Manon Frutschi, Andrea Rinaldo, Paolo Benettin, Mitra Asadollahi, Simiao Wang, Filippo Miele

Reduction-oxidation cycles measured through soil redox potential (Eh) are associated with dynamic soil microbial activity. Understanding changes in the composition of, and resource use by, soil microbial communities requires Eh predictability under shiftin ...

American Geophysical Union2023

Contribution of the nuclear field shift to kinetic uranium isotope fractionation

Rizlan Bernier-Latmani, Ashley Richards Brown

2023

Dataset of scientific article "Variability in Arsenic Methylation Efficiency across Aerobic and Anaerobic Microorganisms"

Rizlan Bernier-Latmani, Karen Elda Viacava Romo, Karin Lederballe Meibom, Arnaud Michel Gelb

Dataset for journal paper entitled "Variability in Arsenic Methylation Efficiency across Aerobic and Anaerobic Microorganisms" (DOI: 10.1021/acs.est.0c03908). Partial publication's abstract: "Microbially-mediated methylation of arsenic (As ...

Zenodo2023

Biostimulation as a sustainable solution for acid neutralization and uranium immobilization post acidic in-situ recovery

Pierre Rossi, Rizlan Bernier-Latmani, Thomas Coral

Major uranium (U) deposits worldwide are exploited by acid leaching, known as 'in-situ recovery' (ISR). ISR involves the injection of an acid fluid into ore-bearing aquifers and the pumping of the resulting metal-containing solution through cation exchange ...

2022

Active anaerobic methane oxidation and sulfur disproportionation in the deep terrestrial subsurface

Rizlan Bernier-Latmani, Manon Frutschi, Emma Bell, Chen Qian

Microbial life is widespread in the terrestrial subsurface and present down to several kilometers depth, but the energy sources that fuel metabolism in deep oligotrophic and anoxic environments remain unclear. In the deep crystalline bedrock of the Fennosc ...

2022

Meta-omics-aided isolation of an elusive anaerobic arsenic-methylating soil bacterium

Rizlan Bernier-Latmani, Karen Elda Viacava Romo, Karin Lederballe Meibom, Matthew Charles Reid, Nicolas Louis Maurice Jacquemin, Jiangtao Qiao

Soil microbiomes harbor unparalleled functional and phylogenetic diversity and are sources of novel metabolisms. However, extracting isolates with a targeted function from complex microbiomes is not straightforward, particularly if the associated phenotype ...

2022