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Johan Jakobsson

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Related publications (3)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

KAP1 controls endogenous retroviruses in embryonic stem cells

Didier Trono, Daniel Constam, Pierre Maillard, Séverine Reynard, Johan Jakobsson, Sonia Verp, Helen Mary Rowe, Jacques Rougemont, Hillary Layard-Liesching

More than forty per cent of the mammalian genome is derived from retroelements, of which about one-quarter are endogenous retroviruses (ERVs). Some are still active, notably in mice the highly polymorphic early transposon (ETn)/MusD and intracisternal A-ty ...

Nature Publishing Group2010

KAP1-mediated epigenetic repression in the forebrain modulates behavioral vulnerability to stress

Jean-Charles Bensadoun, Maria del Carmen Sandi Perez, Maria Isabel Cordero Campana, Reto Bisaz, Didier Trono, Johan Jakobsson, Anna Claire Groner

KAP1 is an essential cofactor of KRAB-zinc finger proteins, a family of vertebrate-specific epigenetic repressors of largely unknown functions encoded in the hundreds by the mouse and human genomes. Here, we report that KAP1 is expressed at high levels and ...

2008

The KRAB repressor domain can trigger de novo promoter methylation during mouse early embryogenesis

Patrick Aebischer, Didier Trono, Friedrich Beermann, Johan Jakobsson, Shuangqing Liao

The Krüppel-associated box (KRAB) domain is a transcriptional repression module responsible for the DNA binding-dependent gene silencing activity of hundreds of vertebrate zinc finger proteins. We previously exploited KRAB-mediated repression within the co ...

2007