Publications by Elena Najdenovska

A multi-scale probabilistic atlas of the human connectome

Meritxell Bach Cuadra, Patric Hagmann, Elena Najdenovska, Alessandra Griffa, Maxime Descoteaux

The human brain is a complex system that can be efficiently represented as a network of structural connectivity. Many imaging studies would benefit from such network information, which is not always available. In this work, we present a whole-brain multi-s ...

NATURE PORTFOLIO2022

Compressed sensing with signal averaging for improved sensitivity and motion artifact reduction in fluorine-19 MRI

Jérôme Yerly, Ruud van Heeswijk, Elena Najdenovska, Tobias Kober, Tom Hilbert

Fluorine-19 (F-19) MRI of injected perfluorocarbon emulsions (PFCs) allows for the non-invasive quantification of inflammation and cell tracking, but suffers from a low signal-to-noise ratio and extended scan time. To address this limitation, we tested the ...

WILEY2020

Improved susceptibility-weighted imaging for high contrast and resolution thalamic nuclei mapping at 7T

Meritxell Bach Cuadra, Elena Najdenovska, José Pedro Rebelo Ferreira Marques, Frédéric Gretsch, João Pedro Forjaco Jorge, Daniel Gallichan, Constantin Tuleasca

Purpose The thalamus is an important brain structure and neurosurgical target, but its constituting nuclei are challenging to image non-invasively. Recently, susceptibility-weighted imaging (SWI) at ultra-high field has shown promising capabilities for tha ...

Wiley2020

Normalization of aberrant pretherapeutic dynamic functional connectivity of extrastriate visual system in patients who underwent thalamotomy with stereotactic radiosurgery for essential tremor: a resting-state functional MRI study

Jean-Philippe Thiran, Meritxell Bach Cuadra, Dimitri Nestor Alice Van De Ville, Elena Najdenovska, Thomas William Arthur Bolton, Constantin Tuleasca

OBJECTIVE The tremor circuitry has commonly been hypothesized to be driven by one or multiple pacemakers within the cerebello-thalamo-cortical pathway, including the cerebellum, contralateral motor thalamus, and primary motor cortex. However, previous stud ...

2020

Partial-volume modeling reveals reduced gray matter in specific thalamic nuclei early in the time course of psychosis and chronic schizophrenia

Meritxell Bach Cuadra, Patric Hagmann, Elena Najdenovska, Zita Rovó, Mario Joao Fartaria de Oliveira, Erick Jorge Canales Rodriguez, Kim Do

The structural complexity of the thalamus, due to its mixed composition of gray and white matter, make it challenging to disjoint and quantify each tissue contribution to the thalamic anatomy. This work promotes the use of partial-volume-based over probabi ...

Wiley2020

Comparison of MRI-based automated segmentation methods and functional neurosurgery targeting with direct visualization of the Ventro-intermediate thalamic nucleus at 7T

Jean-Philippe Thiran, Meritxell Bach Cuadra, Elena Najdenovska, José Pedro Rebelo Ferreira Marques, João Pedro Forjaco Jorge, Daniel Gallichan, Constantin Tuleasca

The ventro-intermediate nucleus (Vim), as part of the motor thalamic nuclei, is a commonly used target in functional stereotactic neurosurgery for treatment of drug-resistant tremor. As it cannot be directly visualized on routinely used magnetic resonance ...

Nature Research2019

Letter: Deep Brain Stimulation of the Pedunculopontine Nucleus Area in Parkinson Disease: Magnetic Resonance Imaging- Based Anatomoclinical Correlations and Optimal Target

Jean-Philippe Thiran, Meritxell Bach Cuadra, Dimitri Nestor Alice Van De Ville, Elena Najdenovska, Constantin Tuleasca, Adrien Jean Régis Maurice Hilaire

OXFORD UNIV PRESS INC2019

Resting-state functional MRI for functional neurosurgery: seeing the light?

Jean-Philippe Thiran, Meritxell Bach Cuadra, Dimitri Nestor Alice Van De Ville, Elena Najdenovska, Constantin Tuleasca

AMER ASSOC NEUROLOGICAL SURGEONS2019

Thalamotomy for tremor normalizes aberrant pre-therapeutic visual cortex functional connectivity

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Elena Najdenovska, Thomas William Arthur Bolton, Constantin Tuleasca

OXFORD UNIV PRESS2019

Pretherapeutic resting-state fMRI profiles are associated with MR signature volumes after stereotactic radiosurgical thalamotomy for essential tremor

Jean-Philippe Thiran, Meritxell Bach Cuadra, Dimitri Nestor Alice Van De Ville, Elena Najdenovska, Thomas William Arthur Bolton, Constantin Tuleasca, Adrien Jean Régis Maurice Hilaire

OBJECTIVE Essential tremor (ET) is the most common movement disorder. Drug-resistant ET can benefit from standard stereotactic deep brain stimulation or radiofrequency thalamotomy or, alternatively, minimally invasive techniques, including stereotactic rad ...

AMER ASSOC NEUROLOGICAL SURGEONS2018

In-vivo probabilistic atlas of human thalamic nuclei based on diffusion-weighted magnetic resonance imaging

Jean-Philippe Thiran, Meritxell Bach Cuadra, Patric Hagmann, Elena Najdenovska, Maxime Descoteaux

The thalamic nuclei are involved in many neurodegenerative diseases and therefore, their identification is of key importance in numerous clinical treatments. Automated segmentation of thalamic subparts is currently achieved by exploring diffusion-weighted ...

NATURE PUBLISHING GROUP2018

Visually-sensitive networks in essential tremor: evidence from structural and functional imaging

Jean-Philippe Thiran, Meritxell Bach Cuadra, Dimitri Nestor Alice Van De Ville, Elena Najdenovska, Constantin Tuleasca

2018