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Paul James Marchand

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Related publications (14)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Targeted capillary photothrombosis via multiphoton excitation of Rose Bengal

Paul James Marchand

Microvascular stalling, the process occurring when a capillary temporarily loses perfusion, has gained increasing interest in recent years through its demonstrated presence in various neuropathologies. Studying the impact of such stalls on the surrounding ...

2023

Soliton microcomb based spectral domain optical coherence tomography

Theo Lasser, Paul James Marchand, Tobias Kippenberg, Martin Hubert Peter Pfeiffer, Junqiu Liu

Spectral domain optical coherence tomography (OCT) is a widely employed, minimally invasive bio-medical imaging technique, which requires a broadband light source, typically implemented by super-luminescent diodes. Recent advances in soliton based photonic ...

Nature Research2021

Supervised learning to quantify amyloidosis in whole brains of an Alzheimer's disease mouse model acquired with optical projection tomography

Theo Lasser, Dimitri Nestor Alice Van De Ville, Aleksandra Radenovic, Paul James Marchand, Virginie Sophie Uhlmann, David Nguyen, Arielle Louise Planchette

Alzheimer's disease (AD) is characterized by amyloidosis of brain tissues. This phenomenon is studied with genetically-modified mouse models. We propose a method to quantify amyloidosis in whole 5xFAD mouse brains, a model of AD. We use optical projection ...

2019