Publications by Sophie Marie Marthe Wurth

Bayesian optimization of peripheral intraneural stimulation protocols to evoke distal limb movements

Sophie Marie Marthe Wurth, Marion Aimée Geneviève Badi-Dubois, Silvestro Micera, Grégoire Courtine, Simon Borgognon

Objective. Motor neuroprostheses require the identification of stimulation protocols that effectively produce desired movements. Manual search for these protocols can be very time-consuming and often leads to suboptimal solutions, as several stimulation pa ...

IOP Publishing Ltd2021

Intrafascicular peripheral nerve stimulation produces fine functional hand movements in primates

Sophie Marie Marthe Wurth, Marion Aimée Geneviève Badi-Dubois, Silvestro Micera, Grégoire Courtine, Evgenia Vladimirova Roussinova, Simon Borgognon

Restoring dexterous hand control is critical for people with paralysis. Approaches based on surface or intramuscular stimulation provide limited finger control, generate insufficient force to recover functional movements, and require numerous electrodes. H ...

AMER ASSOC ADVANCEMENT SCIENCE2021

A versatile robotic platform for the design of natural, three-dimensional reaching and grasping tasks in monkeys

Aude Billard, Sophie Marie Marthe Wurth, Marion Aimée Geneviève Badi-Dubois, Silvestro Micera, Marco Capogrosso, Seyed Sina Mirrazavi Salehian, Sara Conti

Objective. Translational studies on motor control and neurological disorders require detailed monitoring of sensorimotor components of natural limb movements in relevant animal models. However, available experimental tools do not provide a sufficiently ric ...

IOP PUBLISHING LTD2020

A neurostimulation system for central nervous stimulation (cns) and peripheral nervous stimulation (pns)

Sophie Marie Marthe Wurth, Silvestro Micera, Grégoire Courtine

The present disclosure relates to a neuromodulation and/or neurostimulation system comprising at least the following components: at least one sensing unit, at least control unit, at least one stimulation unit, at least one Central Nervous System (CNS) stim ...

2018

Closed-loop control of trunk posture improves locomotion through the regulation of leg proprioceptive feedback after spinal cord injury

Jenifer Cléa Miehlbradt, Sophie Marie Marthe Wurth, Silvestro Micera, Grégoire Courtine, Joachim von Zitzewitz, Eduardo Martin Moraud, Emanuele Formento, Marco Capogrosso

Nature Research2018

Hybrid peripheral-spinal neuroprosthesis for refined motor execution after paralysis

Sophie Marie Marthe Wurth

Spinal cord injury (SCI) disrupts the communication between the brain and the spinal circuits responsible for movement, thereby causing severe motor deficits. Current strategies to restore function to paralyzed limbs have separately investigated electrical ...

EPFL2018

Long-term usability and bio-integration of polyimide-based intraneural stimulating electrodes

Sophie Marie Marthe Wurth, Jérôme Gandar, Nawal Noëlle Kinany, Silvestro Micera, Grégoire Courtine, Stanisa Raspopovic, Quentin Barraud, Alessandra Piersigilli, Marco Capogrosso, Natalia Pavlova, Jacopo Rigosa, Polina Shkorbatova

Stimulation of peripheral nerves has transiently restored lost sensation and has the potential to alleviate motor deficits. However, incomplete characterization of the long-term usability and bio-integration of intra-neural implants has restricted their us ...

Elsevier Sci Ltd2017

Rehabilitative Soft Exoskeleton for Rodents

Sophie Marie Marthe Wurth, Silvestro Micera, Jamie Paik, Grégoire Courtine, Joachim von Zitzewitz, Rubia van den Brand, Eduardo Martin Moraud, Laetitia Danielle Philippine Baud, Juan Manuel Florez Marin, Manan Kishore Shah

Robotic exoskeletons provide programmable, consistent and controllable active therapeutic assistance to patients with neurological disorders. Here we introduce a prototype and preliminary experimental evaluation of a rehabilitative gait exoskeleton that en ...

Institute of Electrical and Electronics Engineers2016

Chronic multichannel neural recordings from soft regenerative microchannel electrodes during gait

Sophie Marie Marthe Wurth, Shreya Narasimhan, Stéphanie Lacour, Katherine Marie Musick, Silvestro Micera, Marco Capogrosso, Jacopo Rigosa

Reliably interfacing a nerve with an electrode array is one of the approaches to restore motor and sensory functions after an injury to the peripheral nerve. Accomplishing this with current technologies is challenging as the electrode-neuron interface ofte ...

Nature Publishing Group2015

A real-time comparison between direct control, sequential pattern recognition control and simultaneous pattern recognition control using a Fitts' law style assessment procedure

Sophie Marie Marthe Wurth

Background: Pattern recognition (PR) based strategies for the control of myoelectric upper limb prostheses are generally evaluated through offline classification accuracy, which is an admittedly useful metric, but insufficient to discuss functional perform ...

BioMed Central2014

A Real Time Performance Assessment of Simultaneous Pattern Recognition Control for Multi-functional Upper Limb Prostheses

Sophie Marie Marthe Wurth

A natural and intuitive operation of multifunctional upper limb prostheses involves the concurrent activation of multiple degrees of freedom in a proportional way. Several approaches to simultaneous and proportional control strategies have been investigate ...

Ieee2013