Publications by Pascal Miéville

Polycondensation as a Universal Method for Preparing High-density Single-atom Catalyst Libraries

Mounir Driss Mensi, Paul Joseph Dyson, Daniel Ortiz Trujillo, Pascal Miéville, Miyeon Chang, Xinbang Wu, Xunhui Wang, Laura Piveteau, Ariana Serban, Timo Markus Oskar Felder, David Fernando Reyes Vasquez

Single-atom catalysts (SACs) present a promising subclass of classic heterogeneous catalysts by maximizing metal dispersion and enhancing efficiency. Although high-density SACs (HD-SACs) are reported, their synthesis is typically constrained to specific me ...

WILEY-V C H VERLAG GMBH2025

GLAS: an open-source easily expandable Git-based scheduling architecture for integral lab automation

Pascal Miéville

This paper presents GLAS (Git-based Lab Automated Scheduler or Get Lab Automation Simplified), an open-source, robust, and highly expandable Git-based architecture designed for laboratory automation. GLAS can be deployed in both partially and fully automat ...

2024

Substance preparation method of capsules and system

Marc Kunze, Pascal Miéville, Florian Patrick Marie Daniel De la Barre De Nanteuil

The present invention concerns an automated substance preparation method comprising: - providing a first substance container containing a first substance; - a step of sampling to extract at least one portion of the first substance; - determination of a mas ...

2024

An apparatus and a method for sealing an opening in a small tubular vessel

Pascal Miéville

The present invention relates to a method and an apparatus for closing sample tubes. Embodiments of the invention use a 3D-printer head having one or more nozzles for delivering viscous polymer material to create a plug in the opening of the sample tube. ...

2024

Swiss CAT plus , a Data-driven Infrastructure for Accelerated Catalysts Discovery and Optimization

Pascal Miéville, Florian Patrick Marie Daniel De la Barre De Nanteuil, Nicolai Cramer

The Catalysis Hub - Swiss CAT+, is a new infrastructure project funded by the ETH Domain, co -head-ed by EPFL and ETHZ. It offers the scientific community a unique integrated technology platform combining automated and high-throughput experimentation with ...

SWISS CHEMICAL SOC2023

Formation pathways of metal–organic frameworks proceeding through partial dissolution of the metastable phase

Pascal Miéville, Berend Smit, Samantha Lynn Anderson, Kyriakos Stylianou, Davide Tiana, Peter George Boyd, Andrzej Gladysiak, Christopher Patrick Ireland, Pascal Alexander Schouwink

2017

In-Vivo Detection and Tracking of T Cells in Various Organs in a Melanoma Tumor Model by F-19-Fluorine MRS/MRI

Lothar Helm, Olivier Michielin, Pascal Miéville, Hikari Ananda Infinity Yoshihara

Background F-19-MRI and F-19-MRS can identify specific cell types after in-vitro or in-vivo F-19-labeling. Knowledge on the potential to track in-vitro F-19-labeled immune cells in tumor models by F-19-MRI/MRS is scarce. Aim To study F-19-based MR techniqu ...

Public Library of Science2016

Photochromic Torsional Switch (PTS): a Light-Driven Actuator for the Dynamic Tuning of π-Conjugation Extension

Anne-Clémence Corminboeuf, Emilie Baudat, Pascal Miéville, Riccardo Petraglia, Luca Cervini, Giuseppe Sforazzini, Adrien Georges Nicolai, Adam Antoni Sobczuk

Here we present a molecular architecture that can reversibly change the geometric conformation of its π-system backbone via irradiation with two different wavelengths. The proposed ‘molecular actuator’ consists of a photoswitchable azobenzene orthogonally ...

2016

Filterable Agents for Hyperpolarization of Water, Metabolites, and Proteins

Geoffrey Bodenhausen, Sami Jannin, Aurélien Bornet, Robert Konrat, Jonas Milani, Pascal Miéville, Basile Vuichoud, Florian Patrick Marie Daniel De la Barre De Nanteuil, Xiao Ji, Estel Canet Martinez

Hyperpolarization is generated by dissolution dynamic nuclear polarization (d-DNP) using a polymer-based polarizing agent dubbed FLAP (filterable labeled agents for polarization). It consists of a thermo-responsive poly(N-isopropylacrylamide), also known a ...

Wiley-V C H Verlag Gmbh2016

Collisional cross-section of water molecules in vapour studied by means of H-1 relaxation in NMR

Geoffrey Bodenhausen, Lothar Helm, Pascal Miéville, Roberto Buratto, Daniele Mammoli, Estel Canet Martinez

In gas phase, collisions that affect the rotational angular momentum lead to the return of the magnetization to its equilibrium (relaxation) in Nuclear Magnetic Resonance (NMR). To the best of our knowledge, the longitudinal relaxation rates R-1 = 1/T-1 of ...

Nature Research2016

A magnetic tunnel to shelter hyperpolarized fluids

Roger Mottier, Geoffrey Bodenhausen, Sami Jannin, Aurélien Bornet, Jonas Milani, Pascal Miéville, Basile Vuichoud

To shield solutions carrying hyperpolarized nuclear magnetization from rapid relaxation during transfer through low fields, the transfer duct can be threaded through an array of permanent magnets. The advantages are illustrated for solutions containing hyp ...

American Institute of Physics2015

Photo-transformation of pedogenic humic acid and consequences for Cd(II), Cu(II) and Pb(II) speciation and bioavailability to green microalga

Pascal Miéville

Humic substances (HS) play key role in toxic metal binding and protecting aquatic microorganisms from metal-induced stress. Any environmental changes that could alter HS concentration and reactivity can be expected to modify metal complexation and thus aff ...

Pergamon-Elsevier Science Ltd2015

Dynamic aggregation of the mid-sized gadolinium complex {Ph-4[Gd(DTTA)(H2O)(2)](-)(3)}

Hugues Jaccard, Lothar Helm, Pascal Miéville

A compound binding three Gd3+ ions, {Ph-4Gd(DTTA)(H2O)(2) (3)} (where H(5)DTTA is diethylenetriaminetetraacetic acid), has been synthesized around a hydrophobic center made up of four phenyl rings. In aqueous solution the molecules start to self-aggre ...

Springer2014

Enantioselective Synthesis of Polycyclic Carbocycles via an Alkynylation-Allylation-Cyclization Strategy

Jérôme Waser, Pascal Miéville, Maria Victoria Vita

A new general three-stage strategy to access polycyclic ring systems bearing all-carbon quaternary centers with high enantioselectivity is reported. The required starting materials were readily accessed in racemic form through the alpha-alkynylation of ket ...

American Chemical Society2014

Surface Functionalisation of Alumina Ceramic Foams with Organic Ligands

Sandrine Gerber, Vincent Laporte, Françoise Borcard, Pascal Miéville, Marc Anthony Caporini

Different anchoring groups have been studied with the aim of covalently binding organic linkers to the surface of alumina ceramic foams. The results suggested that a higher degree of functionalisation was achieved with a pyrogallol derivative - as compared ...

2012

Dynamic Nuclear Polarization and Other Magnetic Ideas at EPFL

Geoffrey Bodenhausen, Martial Rey, Sami Jannin, Aurélien Bornet, Jonas Milani, Simone Ulzega, Pascal Miéville, Marc Anthony Caporini, Nicola Salvi, Diego Carnevale, Roberto Buratto, Srinivas Chinthalapalli, Shutao Wang, Daniele Mammoli, Angel Joaquin Perez Linde

Although nuclear magnetic resonance (NMR) can provide a wealth of information, it often suffers from a lack of sensitivity. Dynamic Nuclear Polarization (DNP) provides a way to increase the polarization and hence the signal intensities in NMR spectra by tr ...

2012

Dynamic nuclear polarization of quadrupolar nuclei using cross polarization from protons: surface-enhanced aluminium-27 NMR

Geoffrey Bodenhausen, Pascal Miéville, Marc Anthony Caporini, Diego Carnevale, David Benjamin Roger Antoine Gajan, David Lyndon Emsley, Aaron James Rossini, Moreno Lelli

The surface of gamma-alumina nanoparticles can be characterized by dynamic nuclear polarization (DNP) surface-enhanced NMR of Al-27. DNP is combined with cross-polarization and MQ-MAS to determine local symmetries of Al-27 sites at the surface. ...

Royal Society of Chemistry2012

Synthesis, complexation and NMR relaxation properties of Gd3+ complexes of Mes(DO3A)3

Hugues Jaccard, Lothar Helm, Pascal Miéville

Medium sized molecules endowed with multiple Gd3+ complexes are efficient high magnetic field MRI contrast agents. The novel ligand Mes(DO3A)3, presenting three DO3A (1,4,7,10-tetraazacyclododecane-N,N′,N′′-triacetatic acid) units grafted on the methyl pos ...

Royal Society of Chemistry2011

Effect of Humic Substance Photoalteration on Lead Bioavailability to Freshwater Microalgae

Pascal Miéville, Julian Spierings

The present study provides results on the influence of humic substance (HS) photoalteration on lead availability to the freshwater microalga Chlorella kesslerii. The evolution of the free lead-ion concentrations measured by the ion exchange technique [Pb]( ...

2011

Chemical Developments in DNP-NMR

Pascal Miéville

The Nuclear Magnetic Resonance (NMR) is an extraordinary tool to understand molecular structures. Its main limitation resides in its relatively low sensitivity when compared with other physico-chemical methods such as Mass Spectrometry (MS) or Optical Spec ...

EPFL2011