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Jackson Eby

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Related publications (3)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Immune Engineering Via Differential Antigen Carriers and Co-Stimulatory Molecules

Jackson Eby

There is an increasing clinical need for vaccines capable of enhancing antigen-specific immune responses and treatments that can induce immunological tolerance toward a single antigen. Here we explore two platforms to enhance either immunization or toleriz ...

EPFL2012

Polymer micelles with pyridyl disulfide-coupled antigen travel through lymphatics and show enhanced cellular responses following immunization

Jeffrey Alan Hubbell, Melody Swartz, Conlin O'Neil, Jackson Eby, Sachiko Hirosue, Karen Dane

Poly(ethylene glycol)-stabilized poly(propylene sulfide) core (PEG-PPS) nanoparticles (NPs) smaller than 50 nm efficiently travel to draining lymph nodes and interact with antigen-presenting cells (APCs) to induce potent immune responses following intrader ...

Elsevier Sci Ltd2012

Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival

Jeffrey Alan Hubbell, Melody Swartz, Conlin O'Neil, Alice Anna Tomei, Jackson Eby, Karen Dane

By delivering immunomodulatory drugs in vivo directly to lymph nodes draining an injection site, an opportunity exists to increase drug bioavailability to local immune cells. Importantly, particles smaller than 100 nm are efficiently transported through ly ...

Elsevier2011