Publications by Muhammed Fatih Toy

Marker-free phase nanoscopy

Christian Depeursinge, Pierre Marquet, Pierre Magistretti, Nicolas Pavillon, Pascal Jourdain, Daniel Boss, Yann Jérôme Michel Pascal Cotte, Muhammed Fatih Toy

We introduce a microscopic method that determines quantitative optical properties beyond the optical diffraction limit and allows direct imaging of unstained living biological specimens. In established holographic microscopy, complex fields are measured us ...

Nature Publishing Group2013

3D Optical Imaging of Living Cells in Microgravity : Application to Study Dynamic Changes of Cytoskeleton

Muhammed Fatih Toy

EPFL2013

Enhanced robustness digital holographic microscopy for demanding environment of space biology

Christian Depeursinge, Jonas Kühn, Muhammed Fatih Toy, Marcel Egli, Stéphane Richard

We describe an optimized digital holographic microscopy system (DHM) suitable for high-resolution visualization of living cells under conditions of altered macroscopic mechanical forces such as those that arise from changes in gravitational force. Experime ...

2012

Accelerated autofocusing of off-axis holograms using critical sampling

Christian Depeursinge, Jérôme Parent, Muhammed Fatih Toy, Marcel Egli, Stéphane Richard

In this Letter we propose a fast off-axis hologram autofocusing (AF) approach that is based on the redundant data elimination by the critical resampling of the contained complex field. Implementation of the proposed methodology enables the real-time AF wit ...

Optical Society of America2012

Beyond the lateral resolution limit by phase imaging

Christian Depeursinge, Yann Jérôme Michel Pascal Cotte, Muhammed Fatih Toy

We present a theory to extend the classical Abbe resolution limit by introducing a spatially varying phase into the illumination beam of a phase imaging system. It allows measuring lateral and axial distance differences between point sources to a higher ac ...

SPIE Society of Photo-optical Instrumentation Engineers2011

Realistic 3D coherent transfer function inverse filtering of complex fields

Christian Depeursinge, Daniel Boss, Cristian Arfire, Yann Jérôme Michel Pascal Cotte, Muhammed Fatih Toy, Shanshan Kou

We present a novel technique for three-dimensional (3D) image processing of complex fields. It consists in inverting the coherent image formation by filtering the complex spectrum with a realistic 3D coherent transfer function (CTF) of a high-NA digital ho ...

Optical Society of America2011

Microscopy image resolution improvement by deconvolution of complex fields

Christian Depeursinge, Nicolas Pavillon, Yann Jérôme Michel Pascal Cotte, Muhammed Fatih Toy

Based on truncated inverse filtering, a theory for deconvolution of complex fields is studied. The validity of the theory is verified by comparing with experimental data from digital holographic microscopy (DHM) using a high-NA system (NA=0.95). Comparison ...

Optical Society of America2010

Digital holographic microscopy real-time monitoring of cytoarchitectural alterations during simulated microgravity

Christian Depeursinge, Jonas Kühn, Jérôme Parent, Christophe Pache, Muhammed Fatih Toy, Marcel Egli

Previous investigations on mammalian cells have shown that microgravity, either that experienced in space, or simulated on earth, causes severe cellular modifications that compromise tissue determination and function. The aim of this study is to investigat ...

SPIE Society of Photo-optical Instrumentation Engineers2010

Sub-Rayleigh resolution by phase imaging

Christian Depeursinge, Nicolas Pavillon, Etienne Shaffer, Yann Jérôme Michel Pascal Cotte, Muhammed Fatih Toy

We report the experimental observation of systematically occurring phase singularities in coherent imaging of sub-Rayleigh distanced objects. A theory that relates the observation to the sub-Rayleigh distance is presented and compared with experimental mea ...

Optical Society of America2010