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Déborah Ley

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Related publications (3)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

MAR elements and transposons for improved transgene integration and expression

Nicolas Mermod, Déborah Ley

Elsevier2014

MAR Elements and Transposons for Improved Transgene Integration and Expression

Nicolas Mermod, Niamh Harraghy, Déborah Ley

Reliable and long-term expression of transgenes remain significant challenges for gene therapy and biotechnology applications, especially when antibiotic selection procedures are not applicable. In this context, transposons represent attractive gene transf ...

2013

MAR-mediated integration of plasmid vectors for in vivo gene transfer and regulation

Andrzej Kulik, Nicolas Mermod, Damien Saugy, Stefania Puttini, Déborah Ley

Background: The in vivo transfer of naked plasmid DNA into organs such as muscles is commonly used to assess the expression of prophylactic or therapeutic genes in animal disease models. Results: In this study, we devised vectors allowing a tight regulatio ...

BioMed Central2013