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Salim Elias Darwiche

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Related publications (5)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Autologous and Allogeneic Cytotherapies for Large Knee (Osteo)Chondral Defects: Manufacturing Process Benchmarking and Parallel Functional Qualification

Sandra Jaccoud, Nathalie Hirt-Burri, Philippe Abdel Sayed, Corinne Scaletta, Salim Elias Darwiche, Cédric Peneveyre, Alexis Laurent, Annick Jeannerat, Robin Martin

Cytotherapies are often necessary for the management of symptomatic large knee (osteo)-chondral defects. While autologous chondrocyte implantation (ACI) has been clinically used for 30 years, allogeneic cells (clinical-grade FE002 primary chondroprogenitor ...

MDPI2023

Development of Standardized Fetal Progenitor Cell Therapy for Cartilage Regenerative Medicine: Industrial Transposition and Preliminary Safety in Xenogeneic Transplantation

Dominique Pioletti, Sandra Jaccoud, Nathalie Hirt-Burri, Philippe Abdel Sayed, Corinne Scaletta, Salim Elias Darwiche, Alexis Laurent

Diverse cell therapy approaches constitute prime developmental prospects for managing acute or degenerative cartilaginous tissue affections, synergistically complementing specific surgical solutions. Bone marrow stimulation (i.e., microfracture) remains a ...

2021

The role of energy dissipation of polymeric scaffolds in the mechanobiological modulation of chondrogenic expression

Dominique Pioletti, Philippe Abdel Sayed, Salim Elias Darwiche, Ulrike Kettenberger

Mechanical stimulation has been proposed to induce chondrogenesis in cell-seeded scaffold. However, the effects of mechanical stimuli on engineered cartilage may vary substantially between different scaffolds. This advocates for the need to identify an ove ...

2014