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Efthymia Vokali

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Related publications (3)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

New immunomodulatory roles of lymphatic endothelium and implications for immunotherapy

Efthymia Vokali

The lymphatic system serves a critical role in fluid homeostasis, lipid metabolism and immune surveillance. The growing appreciation of its implication in various diseases challenges the conventional view of lymphatics as a passive transport system. Tradit ...

EPFL2016

Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response

Jeffrey Alan Hubbell, Melody Swartz, Susan Thomas, Amanda Waite Lund, Efthymia Vokali

Accumulating evidence implicates the tumor-draining lymph node (TDLN) in tumor-induced immune escape, as it drains regulatory molecules and leukocytes from the tumor microenvironment. We asked whether targeted delivery of adjuvant to the TDLN, presumably a ...

Elsevier Sci Ltd2014

Steady-State Antigen Scavenging, Cross-Presentation, and CD8(+) T Cell Priming: A New Role for Lymphatic Endothelial Cells

Melody Swartz, Patricia Corthésy Henrioud, Sachiko Hirosue, Marcela Rincón-Restrepo, Amanda Waite Lund, Efthymia Vokali, Vidya Raghavan

Until recently, the known roles of lymphatic endothelial cells (LECs) in immune modulation were limited to directing immune cell trafficking and passively transporting peripheral Ags to lymph nodes. Recent studies demonstrated that LECs can directly suppre ...

American Association of Immunologists ; Oxford University Press2014