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Evan Graehl Williams

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Related publications (20)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

The mouse metallomic landscape of aging and metabolism

Johan Auwerx, Richardus Houtkooper, Evan Graehl Williams, Pooja Jha, Jean-David Horacio Morel, Ludger Jan Elzuë Goeminne

The metallome is crucial for normal cell functioning but remains largely overlooked in mammals. Here the authors analyze the metallome and copper and zinc isotope compositions in aging mice and show networks of interactions that are organ-specific, age-dep ...

Nature Research2022

A platform for experimental precision medicine: The extended BXD mouse family

Johan Auwerx, Evan Graehl Williams

The challenge of precision medicine is to model complex interactions among DNA variants, phenotypes, development, environments, and treatments. We address this challenge by expanding the BXD family of mice to 140 fully isogenic strains, creating a uniquely ...

CELL PRESS2021

Gene-by-environment modulation of lifespan and weight gain in the murine BXD family

Johan Auwerx, Evan Graehl Williams, Maroun Bou Sleiman, Pooja Jha

How lifespan and body weight vary as a function of diet and genetic differences is not well understood. Here we quantify the impact of differences in diet on lifespan in a genetically diverse family of female mice, split into matched isogenic cohorts fed a ...

NATURE PORTFOLIO2021