Publications by Irene Taurino | EPFL Graph Search

A wearable electrochemical sensing system for non-invasive monitoring of lithium drug in bipolar disorder

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Criscuolo

Lithium represents the main drug for the treatment of Bipolar Disorder (BD) as it acts as a mood stabilizer. However, because of its narrow therapeutic window, psychiatric patients are obliged to frequent tests in hospital to control their lithium blood co ...

2021

All-Solid-State Ion-Selective Electrodes: A Tutorial for Correct Practice

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Mandresy Ivan Ny Hanitra, Francesca Criscuolo

The research on ion-measuring devices has seen a rapid expansion in the last years as a consequence of the growing interest in wearable sensors for biofluids analysis and in portable devices for remote or in-line water and food quality monitoring. As a res ...

2021

Electrochemical Assay for Extremely Selective Recognition of Fructose Based on 4-Ferrocene-Phenylboronic Acid Probe and beta-Cyclodextrins Supramolecular Complex

Sandro Carrara, Irene Taurino, Maria Antonietta Casulli

The aim of the present paper is to highlight a novel electrochemical assay for an extremely-selective detection of fructose thanks to the use of a supramolecular complex between beta-cyclodextrins (beta-CDs) and a chemically modified ferrocene with boronic ...

2020

Wearable multifunctional sweat-sensing system for efficient healthcare monitoring

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Nicolò Oliva, Mandresy Ivan Ny Hanitra, Francesca Criscuolo, Simone Aiassa

Despite the huge expansion in recent years of sweat sensing and wearable technologies, several challenges are still open, including poor sample collection, separate sampling and analysis, low multi-sensing capabilities and materials toxicity. In this work, ...

2020

Integration Methods of Cyclodextrins on Gold and Carbon Electrodes for Electrochemical Sensors

Sandro Carrara, Irene Taurino, Maria Antonietta Casulli

Cyclodextrins (CDs) are oligosaccharides composed of six (α), seven (β) or eight (γ) glucose units. Their inner hydrophobic cavity and hydrophilic external surface enable the formation of the “host-guest inclusion complex” with different organic or inorgan ...

2019

Fast Procedures for the Electrodeposition of Platinum Nanostructures on Miniaturized Electrodes for Improved Ion Sensing

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Criscuolo

Nanostructured materials have attracted considerable interest over the last few decades to enhance sensing capabilities thanks to their unique properties and large surface area. In particular, noble metal nanostructures offer several advantages including h ...

2019

Flexible sweat sensors for non-invasive optimization of lithium dose in psychiatric disorders

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Criscuolo

Lithium is the main mood stabilizer in bipolar disorders and other psychiatric conditions. However, lithium levels in blood must be monitored frequently during therapies because of its narrow therapeutic range. For this reason the patients, whose quality o ...

IEEE2019

Highly-stable Li + ion-selective electrodes based on noble metal nanostructured layers as solid-contacts

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Stradolini, Francesca Criscuolo

Nowadays the development of stable and highly efficient Solid-Contact Ion-Selective Electrodes (SC-ISEs) attracts much attention in the research community because of the great expansion of portable analytical devices. In this work, we present highly stable ...

2018

Performance of Carbon Nano-Scale Allotropes in Detecting Midazolam and Paracetamol in Undiluted Human Serum

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Nima Aliakbarinodehi, Ioulia Tzouvadaki, Francesca Stradolini, Sattar Akbari Nakhjavani

Nano-materials are highly exploited to enhance sensing performance of electrochemical electrodes by increasing the Electro-Active Surface Area (EASA). In this work, an analytical calculation of the deposited EASA is presented and experimentally validated b ...

2018

A novel electrochemical sensor for non-invasive monitoring of lithium levels in mood disorders

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Criscuolo

Lithium is the main drug for the treatment of mood disorders. Due to its narrow therapeutic window, Therapeutic Drug Monitoring (TDM) is a norm during therapy in order to avoid adverse effects. Consequently, patients are obliged to frequent check-ups in ho ...

2018

Cleaning strategy for carbon-based electrodes: Long-term propofol monitoring in human serum

Giovanni Boero, Giovanni De Micheli, Irene Taurino, Francesca Stradolini, Tugba Kilic

In this work, we present a novel electrochemical cleaning procedure for long-term electrochemical monitoring of propofol by using boron-doped diamond (BDD) and pencil graphite electrode (PGE). Propofol is an anesthetic that is widely used for long-lasting ...

2018

Mixed gold and platinum nanostructured layers for all-solid-state ion sensors

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Danilo Demarchi, Francesca Criscuolo, Lucia Lobello

The great interest in portable and wearable monitoring systems has promoted in recent years a major expansion of all-solid-state Ion-Selective Electrodes (ISEs). Nanostructured Solid-Contacts (SCs) have shown a promising potential in order to eliminate the ...

IEEE2018

An electrochemical sensor for quantitative analysis of Rhesus D antibodies in blood

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Tugba Kilic, Francesca Criscuolo

The Hemolytic Disease of the Fetus and Newborn (HDFN), if untreated, can have severe consequences on baby’s health, eventually causing death. Prevention and diagnosis of pregnancies at risk of HDFN consists in quantitative analysis in hospital every 2-4 we ...

IEEE2017

A bimetallic nanocoral Au decorated with Pt nanoflowers (bio)sensor for H2O2 detection at low potential

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Puppo

In this work, we have developed for the first time a method to make novel gold and platinum hybrid bimetallic nanostructures differing in shape and size. Au-Pt nanostructures were prepared by electrodeposition in two simple steps. The first step consists o ...

Academic Press Inc Elsevier Science2017

A Differential Electrochemical Readout ASIC with Heterogeneous Integration of Bio-nano Sensors for Amperometric Sensing

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Seyedeh Sara Ghoreishizadeh

A Monolithic biosensing platform is presented for miniaturized amperometric electrochemical sensing in CMOS. The system consists of a fully-integrated current readout circuit for differential current measurement as well as on-die sensors developed by growi ...

2017

Study on the bio-functionalization of memristive nanowires for optimum memristive biosensors

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Ioulia Tzouvadaki

Semiconductor nanowires are emerging as promising building blocks for biosensors enabling direct electrical detection of various biomolecules. In this framework, two-terminal Schottky-barrier silicon (Si) nanowire arrays that exhibit memristive electrical ...

Royal Society of Chemistry2016

Wireless Monitoring of Endogenous and Exogenous Biomolecules on an Android Interface

Giovanni De Micheli, Cristina Boero, Sandro Carrara, Irene Taurino, Camilla Baj-Rossi, Grégoire Casimir Joseph Surrel, Stefano Riario, Francesca Stradolini

Monitoring patients in intensive care units is generally expensive and time consuming. A prompter medical intervention for those critical patients is a key factor for their safety. Therefore, a system that offers immediate visualization of the monitored da ...

Institute of Electrical and Electronics Engineers2016

Google Glass-Directed Monitoring and Control of Microfluidic Biosensors and Actuators

Sandro Carrara, Irene Taurino, Danilo Demarchi

Google Glass is a recently designed wearable device capable of displaying information in a smartphone-like hands-free format by wireless communication. The Glass also provides convenient control over remote devices, primarily enabled by voice recognition c ...

Nature Research2016

Bubble electrodeposition of gold porous nanocorals for the enzymatic and non-enzymatic detection of glucose

Sandro Carrara, Irene Taurino

Au nanocorals are grown on gold screen-printed electrodes (SPEs) by using a novel and simple one-step electro-deposition process. Scanning electron microscopy was used for the morphological characterization. The devices were assembled on a three-electrode ...

Elsevier2016

Platinum nanopetal-based potassium sensors for acute cell death monitoring

Giovanni De Micheli, Sandro Carrara, Irene Taurino

Growing interest in the role of ions as cell death regulators has led to the consideration of K+, which plays a major role in events such as necrosis, apoptosis and osmotic shock. These mechanisms induce effluxes of K+, which can be m ...

RSC Publishing2016