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Sarah Thurnheer

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Related publications (3)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Population Variation and Genetic Control of Modular Chromatin Architecture in Humans

David Hacker, Gilles Udin, Nouria Hernandez, Bart Deplancke, Alisa Yurovsky, Sunil Kumar Raghav, Sarah Thurnheer, Sebastian Martin Waszak

Chromatin state variation at gene regulatory elements is abundant across individuals, yet we understand little about the genetic basis of this variability. Here, we profiled several histone modifications, the transcription factor (TF) PU.1, RNA polymerase ...

Elsevier2015

Coordinated Effects of Sequence Variation on DNA Binding, Chromatin Structure, and Transcription

David Hacker, Gilles Udin, Julien Bryois, Nouria Hernandez, Bart Deplancke, Alisa Yurovsky, Sunil Kumar Raghav, Sarah Thurnheer, Sebastian Martin Waszak

DNA sequence variation has been associated with quantitative changes in molecular phenotypes such as gene expression, but its impact on chromatin states is poorly characterized. To understand the interplay between chromatin and genetic control of gene regu ...

American Association for the Advancement of Science2013

Polyethyleneimine-based transient gene expression processes for suspension-adapted HEK-293E and CHO-DG44 cells

Florian Maria Wurm, Lucia Baldi Unser, David Hacker, Divor Kiseljak, Yashas Rajendra, Sarah Thurnheer

Transient gene expression (TGE) from mammalian cells is an increasingly important tool for the rapid production of recombinant proteins for research applications in biochemistry, structural biology, and biomedicine. Here we review methods for the transfect ...

Elsevier2013