Publications by Solène Marcelle Françoise Marie Passemard

Novel trehalose-based excipients for stabilizing nebulized anti-SARS-CoV-2 antibody

Sandrine Gerber, François Rémi Pierre Noverraz, Solène Marcelle Françoise Marie Passemard

COVID-19 is caused by the infection of the lungs by SARS-CoV-2. Monoclonal antibodies, such as sotrovimab, showed great efficiency in neutralizing the virus before its internalization by lung epithelial cells. However, parenteral routes are still the prefe ...

2023

Beneficial effects of Human Mesenchymal Stromal Cells on Porcine Hepatocyte Viability and Albumin Secretion

Sandrine Gerber, François Rémi Pierre Noverraz, Solène Marcelle Françoise Marie Passemard, Aurélien Thomas, Luca Szabó

Porcine hepatocytes transplanted during acute liver failure might support metabolic functions until the diseased liver recovers its function. Here, we isolated high numbers of viable pig hepatocytes and evaluated hepatocyte functionality after encapsulatio ...

2018

Beneficial Effects of Human Mesenchymal Stromal Cells on Porcine Hepatocyte Viability and Albumin Secretion

Sandrine Gerber, François Rémi Pierre Noverraz, Solène Marcelle Françoise Marie Passemard, Aurélien Thomas, Luca Szabó

LIPPINCOTT WILLIAMS & WILKINS2018

Hydrogels based on functionalized polysaccharides

Jutta Christine Wandrey, Sandrine Gerber, Léo Bühler, Solène Marcelle Françoise Marie Passemard

The present invention relates to functionalized hydrogel networks grafted with at least one moiety for use in numerous fields, from cosmetics to surgery and medicine. ...

2018

Multi-harmonic imaging in the second near-infrared window of nanoparticle-labeled stem cells as effective monitoring tool in tissue depth

Sandrine Gerber, Luigi Bonacina, Solène Marcelle Françoise Marie Passemard

In order to assess the therapeutic potential of cell-based strategies, it is of paramount importance to elaborate and validate new tools for monitoring the behavior of injected cells in terms of tissue dissemination and engraftment properties. Here, we app ...

American Chemical Society2017

Synthesis strategies to extend the variety of alginate-based hybrid hydrogels for cell microencapsulation

Jutta Christine Wandrey, Sandrine Gerber, François Rémi Pierre Noverraz, Solène Marcelle Françoise Marie Passemard, Luca Szabó

The production of hydrogel microspheres (MS) for cell immobilization, maintaining the favorable properties of alginate gels but presenting enhanced performance in terms of in vivo durability and physical properties, is desirable to extend the therapeutic p ...

American Chemical Society2017

Beneficial effects of human mesenchymal stromal cells on porcine hepatocytes viability and albumin secretion

Sandrine Gerber, Léo Bühler, Solène Marcelle Françoise Marie Passemard, Aurélien Thomas

Wiley2017

Contribution of polymeric materials to progress in xenotransplantation of microencapsulated cells - A review

Jutta Christine Wandrey, Sandrine Gerber, Redouan Mahou, François Rémi Pierre Noverraz, Solène Marcelle Françoise Marie Passemard

Cell microencapsulation and subsequent transplantation of the microencapsulated cells require multidisciplinary approaches. Physical, chemical, biological, engineering, and medical expertise has to be combined. Several natural and synthetic polymeric mater ...

2016

Hydrogels based on functionalized polysaccharides

Jutta Christine Wandrey, Sandrine Gerber, Léo Bühler, Solène Marcelle Françoise Marie Passemard

The present invention relates to a functionalized hydrogel network grafted with at least one moiety for use in numerous fields, from cosmetics to surgery and medicine. ...

Technology Transfer Office EPFL, Swiss Federal Institute of Intellectual Property2016

Cellular uptake and biocompatibility of bismuth ferrite harmonic advanced nanoparticles

Daniel Rytz, Jean-Pierre Wolf, Sandrine Gerber, Luigi Bonacina, Stephanie Hwu, Solène Marcelle Françoise Marie Passemard, Davide Städler

Bismuth Ferrite (BFO) nanoparticles (BFO-NP) display interesting optical (nonlinear response) and magnetic properties which make them amenable for bio-oriented diagnostic applications as intra- and extra membrane contrast agents. Due to the relatively rece ...

Elsevier2015

Human mesenchymal stromal cells improve survival and function of pancreatic iislets by cell-to-cell contact through N-cadherin

Jutta Christine Wandrey, Sandrine Gerber, Redouan Mahou, François Rémi Pierre Noverraz, Solène Marcelle Françoise Marie Passemard

Wiley-Blackwell2015

Human Mesenchymal Stromal Cells Improve Survival And Function Of Pancreatic Islets By Cell-To-Cell Contact

Jutta Christine Wandrey, Sandrine Gerber, Redouan Mahou, Léo Bühler, Solène Marcelle Françoise Marie Passemard

Wiley-Blackwell2015

Functionalized bismuth ferrite harmonic nanoparticles for cancer cells labelling and imaging

Sandrine Gerber, Luigi Bonacina, Giona Sonego, Solène Marcelle Françoise Marie Passemard, Davide Städler

Bismuth ferrite (BFO) harmonic nanoparticles (NPs) display high nonlinear optical efficiency and excellent biocompatibility profile which make them attractive for the development of diagnostic applications as contrast agents. In this study, we present a ge ...

Springer Verlag2015

Tuning the Properties of Hydrogel Microspheres by Adding Chemical Cross-linking Functionality to Sodium Alginate

Jutta Christine Wandrey, Sandrine Gerber, Redouan Mahou, Françoise Borcard, Léo Bühler, François Rémi Pierre Noverraz, Virginia Crivelli, Solène Marcelle Françoise Marie Passemard

Two novel types of hydrogel microspheres (MS) are presented. First, one-component microspheres (1-comMS) were produced from sodium alginate (Na-alg) equipped with thiolfunctionalized hydroxyl groups. The functionalization pathway included the conversion of ...

American Chemical Society2015

Human Mesenchymal Stromal Cells Improve Survival And Function Of Pancreatic Iislets By Cell-To-Cell Contact Through N-Cadherin

Jutta Christine Wandrey, Sandrine Gerber, Redouan Mahou, François Rémi Pierre Noverraz, Solène Marcelle Françoise Marie Passemard

Lippincott Williams & Wilkins2015

Simultaneous Multi-Harmonic Imaging of Nanoparticles in Tissues for Increased Selectivity

Jean-Pierre Wolf, Sandrine Gerber, Luigi Bonacina, Sébastien Courvoisier, Solène Marcelle Françoise Marie Passemard, Davide Städler

We investigate the use of Bismuth Ferrite (BFO) nanoparticles for tumor tissue labelling in combination with infrared multi-photon excitation at 1250 nm. We report the efficient and simultaneous generation of second and third harmonic by the nanoparticles. ...

Amer Chemical Soc2015

Deep UV generation and direct DNA photo-interaction by harmonic nanoparticles in labelled samples

Daniel Rytz, Jean-Pierre Wolf, Sandrine Gerber, Luigi Bonacina, Solène Marcelle Françoise Marie Passemard, Davide Städler

A biophotonics approach based on the nonlinear optical process of second harmonic generation is presented and demonstrated on malignant human cell lines labelled by harmonic nanoparticles. The method enables independent imaging and therapeutic action, sele ...

Royal Society of Chemistry2014

Drug Screening Boosted by Hyperpolarized Long-Lived States in NMR

Geoffrey Bodenhausen, Sandrine Gerber, Sami Jannin, Aurélien Bornet, Jonas Milani, Basile Vuichoud, Nicola Salvi, Solène Marcelle Françoise Marie Passemard, Roberto Buratto, Aurélien Laguerre, Daniele Mammoli, Maninder Singh

Transverse and longitudinal relaxation times (T11 and T1) have been widely exploited in NMR to probe the binding of ligands and putative drugs to target proteins. We have shown recently that long-lived states (LLS) can be more sensitive to ligand binding. ...

Wiley-Blackwell2014

Functionalization of Nanoparticles for Targeted Cancer Imaging and Diagnosis

Solène Marcelle Françoise Marie Passemard

At present time, cancer is the leading cause of death in developed countries. The medical imaging tools currently used in clinics such as radiology, nuclear magnetic resonance imaging, microscopy and endoscopy are not able to reach the sensitivity necessar ...

EPFL2014

Nonlinear optical and magnetic properties of BiFeO3 harmonic nanoparticles

Daniel Rytz, Jean-Pierre Wolf, Sandrine Gerber, Luigi Bonacina, Solène Marcelle Françoise Marie Passemard, Davide Städler

Second Harmonic Generation (SHG) from BiFeO3 nanocrystals is investigated for the first time to determine their potential as biomarkers for multiphoton imaging. Nanocrystals are produced by an auto-combustion method with 2-amino-2-hydroxymethyl-propane-1,3 ...

American Institute of Physics2014