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Yu Chen

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Related publications (11)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Path and Intersections: Characterization of Quasi-metrics in Directed Okamura-Seymour Instances

We study the following distance realization problem. Given a quasi-metric D on a set T of terminals, does there exist a directed Okamura-Seymour graph that realizes D as the (directed) shortest-path distance metric on T? We show that, if we are further giv ...

Society for Industrial and Applied Mathematics2025

On the Streaming Complexity of Expander Decomposition

Mikhail Kapralov, Yu Chen, Mikhail Makarov

In this paper we study the problem of finding (ϵ, ϕ)-expander decompositions of a graph in the streaming model, in particular for dynamic streams of edge insertions and deletions. The goal is to partition the vertex set so that every component induces a ϕ- ...

Schloss Dagstuhl- Leibniz-Zentrum fur Informatik GmbH, Dagstuhl Publishing2024

Lineage plasticity in prostate cancer depends on JAK/STAT inflammatory signaling

Yu Chen, Wouter Richard Karthaus, Jillian Rose Love

Drug resistance in cancer is often linked to changes in tumor cell state or lineage, but the molecular mechanisms driving this plasticity remain unclear. Using murine organoid and genetically engineered mouse models, we investigated the causes of lineage p ...

American Association for the Advancement of Science (AAAS)2022