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Anders Meibom

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Related publications (123)

En route to ion microprobe analysis of soluble compounds at single cell level: The CryoNanoSIMS

Arnaud Comment, Tian Cheng, Anders Meibom, Stéphane Laurent Escrig, Florent Olivier Vivien Plane, Louise Helene Soegaard Jensen

2016

Realization of sub-cellular resolution cryogenic ion microprobeimaging with vitrified samples

Arnaud Comment, Tian Cheng, Anders Meibom, Stéphane Laurent Escrig, Florent Olivier Vivien Plane, Louise Helene Soegaard Jensen

2016

A unique coral biomineralization pattern has resisted 40 million years of major ocean chemistry change

Anders Meibom, Isabelle Domart-Coulon, Jaroslaw Hubert Stolarski

Today coral reefs are threatened by changes to seawater conditions associated with rapid anthropogenic global climate change. Yet, since the Cenozoic, these organisms have experienced major fluctuations in atmospheric CO2 levels (from greenhouse conditions ...

Nature Research2016

Evidence for Rhythmicity Pacemaker in the Calcification Process of Scleractinian Coral

Anders Meibom, Isabelle Domart-Coulon, Jaroslaw Hubert Stolarski

Reef-building scleractinian (stony) corals are among the most efficient bio-mineralizing organisms in nature. The calcification rate of scleractinian corals oscillates under ambient light conditions, with a cyclic, diurnal pattern. A fundamental question i ...

Nature Research2016

NanoSIMS analysis of an isotopically labelled organometallic ruthenium(II) drug to probe its distribution and state in vitro

Kai Johnsson, Paul Joseph Dyson, Graham Knott, Mary-Claude Croisier-Coeytaux, Anders Meibom, Stéphane Laurent Escrig

The in vitro inter-and intra-cellular distribution of an isotopically labelled ruthenium(II)-arene (RAPTA) anti-metastatic compound in human ovarian cancer cells was imaged using nano-scale secondary ion mass spectrometry (NanoSIMS). Ultra-high resolution ...

Royal Society of Chemistry2015

Imaging the time-integrated cerebral metabolic activity with subcellular resolution through nanometer-scale detection of biosynthetic products deriving from (13)C-glucose

Arnaud Comment, Graham Knott, Yuhei Takado, Anders Meibom, Stéphane Laurent Escrig, Mojgan Masoodi

Glucose is the primary source of energy for the brain but also an important source of building blocks for proteins, lipids, and nucleic acids. Little is known about the use of glucose for biosynthesis in tissues at the cellular level. We demonstrate that l ...

Elsevier2015

Imaging liver and brain glycogen metabolism at the nanometer scale

Arnaud Comment, Graham Knott, Yuhei Takado, Anders Meibom, Stéphane Laurent Escrig, Mojgan Masoodi

In mammals, glycogen synthesis and degradation are dynamic processes regulating blood and cerebral glucose-levels within a well-defined physiological range. Despite the essential role of glycogen in hepatic and cerebral metabolism, its spatiotemporal distr ...

Elsevier Science Bv2015

MALDI-MS and NanoSIMS imaging techniques to study cnidarian-dinoflagellate symbioses

Anders Meibom, Christophe Kopp

Cnidarian-dinoflagellate photosynthetic symbioses are fundamental to biologically diverse and productive coral reef ecosystems. The hallmark of this symbiotic relationship is the ability of dinoflagellate symbionts to supply their cnidarian host with a wid ...

Elsevier Gmbh, Urban & Fischer Verlag2015

Phenotypic heterogeneity in metabolic traits among single cells of a rare bacterial species in its natural environment quantified with a combination of flow cell sorting and NanoSIMS

Anders Meibom, Stéphane Laurent Escrig, Martin Ackermann

Populations of genetically identical microorganisms residing in the same environment can display marked variability in their phenotypic traits; this phenomenon is termed phenotypic heterogeneity. The relevance of such heterogeneity in natural habitats is u ...

Frontiers Media SA2015

NanoSIMS analysis of an isotopically labelled organometallic ruthenium(II) drug to probe its distribution and state in vitro

Kai Johnsson, Paul Joseph Dyson, Graham Knott, Mary-Claude Croisier-Coeytaux, Anders Meibom, Stéphane Laurent Escrig

Royal Society of Chemistry2015

Morphology, microstructure, crystallography, and chemistry of distinct CaCO3 deposits formed by early recruits of the scleractinian coral Pocillopora damicornis

Duncan Thomas Lindsay Alexander, Anders Meibom, Melany Melissa Gilis, Jaroslaw Hubert Stolarski

Scleractinian corals begin their biomineralization process shortly after larval settlement with the formation of calcium carbonate (CaCO3) structures at the interface between the larval tissues and the substrate. The newly settled larvae exert variable deg ...

Wiley-Blackwell2015

A nanoscale secondary ion mass spectrometry study of dinoflagellate functional diversity in reef-building corals

Anders Meibom, Isabelle Domart-Coulon

Nutritional interactions between corals and symbiotic dinoflagellate algae lie at the heart of the structural foundation of coral reefs. Whilst the genetic diversity of Symbiodinium has attracted particular interest because of its contribution to the sensi ...

Wiley-Blackwell2015

Subcellular Investigation of Photosynthesis-Driven Carbon and Nitrogen Assimilation and utilization in the Symbiotic Reef Coral: Pocillopora damicornis

Anders Meibom, Stéphane Laurent Escrig, Christophe Kopp, Isabelle Domart-Coulon

UNLABELLED: Reef-building corals form essential, mutualistic endosymbiotic associations with photosynthetic Symbiodinium dinoflagellates, providing their animal host partner with photosynthetically derived nutrients that allow the coral to thrive in oligot ...

American Society for Microbiology2015

Simultaneous extension of both basic microstructural components in scleractinian coral skeleton during night and daytime, visualized by in situ Sr-86 pulse labeling

Anders Meibom, Isabelle Domart-Coulon, Jaroslaw Hubert Stolarski

Using in situ (12 h) pulse-labeling of scleractinian coral aragonitic skeleton with stable 86Sr isotope, the diel pattern of skeletal extension was investigated in the massive Porites lobata species, grown at 5 m depth in the Gulf of Eilat Several microstr ...

Elsevier2014

Ultrascale and Microscale Growth Dynamics of the Cidaroid Spine of Phyllacanthus imperialis Revealed by Mg-26 Labeling and NanoSIMS Isotopic Imaging

Anders Meibom, Stéphane Laurent Escrig, Jaroslaw Hubert Stolarski

Growth dynamics of the primary spine of the cidaroid sea urchin Phyllacanthus imperialis was assessed for the first time using pulsed Mg-26-labeling and NanoSIMS isotopic imaging. The sea urchin was incubated twice (for 48 h) in artificial seawater with el ...

Wiley-Blackwell2014

Biomineralization in Newly Settled Recruits of the Scleractinian Coral Pocillopora damicornis

Anders Meibom, Melany Melissa Gilis, Isabelle Domart-Coulon, Jaroslaw Hubert Stolarski

Calcium carbonate biomineralization of scleractinian coral recruits is fundamental to the construction of reefs and their survival under stress from global and local environmental change. Establishing a baseline for how normal, healthy coral recruits initi ...

Wiley-Blackwell2014

Highly Dynamic Cellular-Level Response of Symbiotic Coral to a Sudden Increase in Environmental Nitrogen

Duncan Thomas Lindsay Alexander, Anders Meibom, Christophe Kopp, Isabelle Domart-Coulon

Metabolic interactions with endosymbiotic photosynthetic dinoflagellate Symbiodinium spp. are fundamental to reef-building corals (Scleractinia) thriving in nutrient-poor tropical seas. Yet, detailed understanding at the single-cell level of nutrient assim ...

American Society for Microbiology2013

Scleractinian coral cell proliferation is reduced in primary culture of suspended multicellular aggregates compared to polyps

Shirit Cohen, Anders Meibom, Agathe Eliette Marie Lecointe, Stéphanie Kéren Cohen, Isabelle Domart-Coulon

Cell cultures from reef-building scleractinian corals are being developed to study the response of these ecologically important organisms to environmental stress and diseases. Despite the importance of cell division to support propagation, cell proliferati ...

Springer2013

Micro- to nanostructure and geochemistry of extant crinoidal echinoderm skeletons

Anders Meibom, Jaroslaw Hubert Stolarski

This paper reports the results of micro- to nanostructural and geochemical analyses of calcitic skeletons from extant deep-sea stalked crinoids. Fine-scale (SEM, FESEM, AFM) observations show that the crinoid skeleton is composed of carbonate nanograins, a ...

Wiley-Blackwell2013

NanoSIMS: Technical Aspects and Applications in Cosmochemistry and Biological Geochemistry

Shirit Cohen, Anders Meibom, Stéphanie Kéren Cohen

The NanoSIMS ion probe is a new-generation SIMS instrument, characterised by superior spatial resolution, high sensitivity and multi-collection capability. Isotope studies of certain elements can be conducted with 50-100nm resolution, making the NanoSIMS a ...

Wiley-Blackwell2013

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