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Sinan Kilic

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Related publications (8)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Release of linker histone from the nucleosome driven by polyelectrolyte competition with a disordered protein

Beat Fierz, Sinan Kilic

Highly charged intrinsically disordered proteins are essential regulators of chromatin structure and transcriptional activity. Here we identify a surprising mechanism of molecular competition that relies on the pronounced dynamical disorder present in thes ...

NATURE PORTFOLIO2022

SUV39 SET domains mediate crosstalk of heterochromatic histone marks

Nora Guidotti, Beat Fierz, Sinan Kilic

Y The SUV39 class of methyltransferase enzymes deposits histone H3 lysine 9 di- and trimethylation (H3K9me2/3), the hallmark of constitutive heterochromatin. How these enzymes are regulated to mark specific genomic regions as heterochromatic is poorly unde ...

eLIFE SCIENCES PUBL LTD2021

Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α

Louise Catherine Bryan, Beat Fierz, Sinan Kilic, Iuliia Boichenko

The dynamic architecture of chromatin fibers, a key determinant of genome regulation, is poorly understood. Here, we employ multimodal single-molecule Förster resonance energy transfer studies to reveal structural states and their interconversion kinetics ...

Nature Research2018