Daniel Strebinger

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Related publications (4)

Endogenous fluctuations of OCT 4 and SOX 2 bias pluripotent cell fate decisions

Cédric Deluz, David Michael Suter, Daniel Strebinger, Andrea Brigitta Alber, Torgil Elias Friman, Subashika Govindan

SOX2 and OCT4 are pioneer transcription factors playing a key role in embryonic stem (ES) cell self‐renewal and differentiation. How temporal fluctuations in their expression levels bias lineage commitment is unknown. Here, we generated knock‐in reporter f ...

2019

Quantitative analysis of SOX2 and OCT4 expression in pluripotency and differentiation

Daniel Strebinger

Embryonic stem (ES) cells have the capacity to give rise to all cell types of the adult organism and can be used as a model to study early cell fate decisions as they closely recapitulate in vivo events. The M and G1 phases have been suggested to be the ke ...

EPFL2018

Endogenous fluctuations of OCT4 and SOX2 bias pluripotent cell fate decisions

Cédric Deluz, David Michael Suter, Daniel Strebinger, Andrea Brigitta Alber, Torgil Elias Friman, Subashika Govindan

MARY ANN LIEBERT, INC2018

A role for mitotic bookmarking of SOX2 in pluripotency and differentiation

Cédric Deluz, Mahé Cécile Raccaud, Suliana Manley, Marion Leleu, Aleksandr Benke, Andrea Callegari, David Michael Suter, Daniel Strebinger, Torgil Elias Friman

Mitotic bookmarking transcription factors remain bound to chromosomes during mitosis and were proposed to regulate phenotypic maintenance of stem and progenitor cells at the mitosis-to-G1 (M-G1) transition. However, mitotic bookmarking remains largely unex ...

Cold Spring Harbor Laboratory2016

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