Publications by Luca Pegolotti

Model order reduction of flow based on a modular geometrical approximation of blood vessels

We are interested in a reduced order method for the efficient simulation of blood flow in arteries. The blood dynamics is modeled by means of the incompressible Navier–Stokes equations. Our algorithm is based on an approximated domain-decomposition of the ...

2021

Deep Neural Network to Accurately Predict Left Ventricular Systolic Function Under Mechanical Assistance

Simone Deparis, Luca Pegolotti

Characterizing left ventricle (LV) systolic function in the presence of an LV assist device (LVAD) is extremely challenging. We developed a framework comprising a deep neural network (DNN) and a 0D model of the cardiovascular system to predict parameters o ...

FRONTIERS MEDIA SA2021

Reduction techniques for PDEs built upon Reduced Basis and Domain Decomposition Methods with applications to hemodynamics

Luca Pegolotti

This thesis focuses on the development and validation of a reduced order technique for cardiovascular simulations. The method is based on the combined use of the Reduced Basis method and a Domain Decomposition approach and can be seen as a particular imple ...

EPFL2021

Implementation and Calibration of a Deep Neural Network to Predict Parameters of Left Ventricular Systolic Function Based on Pulmonary and Systemic Arterial Pressure Signals

Simone Deparis, Jean Bonnemain, Luca Pegolotti

The evaluation of cardiac contractility by the assessment of the ventricular systolic elastance function is clinically challenging and cannot be easily obtained at the bedside. In this work, we present a framework characterizing left ventricular systolic f ...

2020

Data driven approximation of parametrized PDEs by reduced basis and neural networks

Simone Deparis, Luca Pegolotti, Niccolò Dal Santo

ACADEMIC PRESS INC ELSEVIER SCIENCE2020

Coupling non-conforming discretizations of PDEs by spectral approximation of the Lagrange multiplier space

Simone Deparis, Luca Pegolotti, Antonio Iubatti

This work focuses on the development of a non-conforming method for the coupling of PDEs based on weakly imposed transmission conditions: the continuity of the global solution is enforced by a finite number of Lagrange multipliers defined over the interfac ...

2019

Isogeometric Analysis of the electrophysiology in the human heart: Numerical simulation of the bidomain equations on the atria

Alfio Quarteroni, Luca Dede', Luca Pegolotti

We consider Isogeometric Analysis (IGA) for the numerical solution of the electrophysiology of the atria, which in this work is modeled by means of the bidomain equations on thin surfaces. First, we consider the bidomain equations coupled with the Roger-Mc ...

ELSEVIER SCIENCE SA2019

Application of the Rosenbrock methods to the solution of unsteady 3D incompressible Navier-Stokes equations

Michel Deville, Alfio Quarteroni, Simone Deparis, Luca Pegolotti, Filippo Menghini

We consider the Rosenbrock methods, namely a family of methods for Differential Algebraic Equations, for the solution of the unsteady three-dimensional Navier-Stokes equations. These multistage schemes are attractive for non-linear problems because they ac ...

2018