Publications by Roman Chrast | EPFL Graph Search

Nerve Regeneration Following Ablation Of Monocarboxylate Transporters 1, 2 And 4 From Schwann Cells

WILEY2022

Altered interplay between endoplasmic reticulum and mitochondria in Charcot-Marie-Tooth type 2A neuropathy

Bernard Schneider, Cylia Cloé Rochat, Mary-Claude Croisier-Coeytaux, Manisha Juneja, Omar El Mansour, Catherine Maclachlan, Roman Chrast, Nathalie Marie Géraldine Bernard

Mutations in the MFN2 gene encoding Mitofusin 2 lead to the development of Charcot-Marie-Tooth type 2A (CMT2A), a dominant axonal form of peripheral neuropathy. Mitofusin 2 is localized at both the outer membrane of mitochondria and the endoplasmic reticul ...

National Academy of Sciences2019

Endoplasmic reticulum and mitochondria in diseases of motor and sensory neurons: a broken relationship?

Bernard Schneider, Roman Chrast, Nathalie Marie Géraldine Bernard

Nature Publishing Group2018

PFN2 and GAMT as common molecular determinants of axonal Charcot-Marie-Tooth disease

Bernard Schneider, Manisha Juneja, Roman Chrast, Nathalie Marie Géraldine Bernard

2018

Characterization Of Motor And Sensory Neuronal Dysfunction In Both In Vitro And In Vivo Models Of Cmt2A Pathology

Bernard Schneider, Cylia Cloé Rochat, Roman Chrast, Nathalie Marie Géraldine Bernard

Wiley-Blackwell2016

Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration

Roman Chrast, Nathalie Marie Géraldine Bernard

Mutations in SIGMAR1, which encodes the Sigma 1 receptor, cause a familial form of amyotrophic lateral sclerosis, but the underlying molecular mechanisms are unclear. Bernard-Marissal et al. reveal that disruption of Sigma 1 receptor function disturbs endo ...

Oxford University Press2015

Reply: Is SIGMAR1 a confirmed FTD/MND gene?

Roman Chrast, Nathalie Marie Géraldine Bernard

Oxford University Press2015

The Glucocorticoid-Induced Leucine Zipper (Gilz/Tsc22d3-2) Gene Locus Plays a Crucial Role in Male Fertility

Friedrich Beermann, Anne Wilson, Roman Chrast, Jian Wang

The glucocorticoid-induced leucine zipper (Tsc22d3-2) is a widely expressed dexamethasone-induced transcript that has been proposed to be important in immunity, adipogenesis, and renal sodium handling based on in vitro studies. To address its function in v ...

2012