Publications by Jose Vicente Sanchez Mut

The HDAC inhibitor CI-994 acts as a molecular memory aid by facilitating synaptic and intracellular communication after learning

Johannes Gräff, Jose Vicente Sanchez Mut, Allison Marie Burns, Giulia Santoni

Long-term memory formation relies on synaptic plasticity, neuronal activity-dependent gene transcription, and epigenetic modifications. Multiple studies have shown that HDAC inhibitor (HDACi) treatments can enhance individual aspects of these processes and ...

2022

Comprehensive analysis of PM20D1 QTL in Alzheimer's disease

Liliane Glauser, Johannes Gräff, Jose Vicente Sanchez Mut

Background Alzheimer's disease (AD) is a complex disorder caused by a combination of genetic and non-genetic risk factors. In addition, an increasing evidence suggests that epigenetic mechanisms also accompany AD. Genetic and epigenetic factors are not ind ...

2020

Membrane activity detection in cultured cells using phase-sensitive plasmonics

Liliane Glauser, Johannes Gräff, Xiaokang Li, Jose Vicente Sanchez Mut, Yasaman Jahani, Foziyeh Sohrabi, Ershad Mohammadi

Despite the existence of various neural recording and mapping techniques, there is an open territory for the emergence of novel techniques. The current neural imaging and recording techniques suffer from invasiveness, a time-consuming labeling process, poo ...

2020

Psychotropic drug-induced genetic-epigenetic modulation of CRTC1 gene is associated with early weight gain in a prospective study of psychiatric patients

Aurélie Delacrétaz, Johannes Gräff, Jose Vicente Sanchez Mut, Céline Dubath

Background: Metabolic side effects induced by psychotropic drugs represent a major health issue in psychiatry. CREB-regulated transcription coactivator 1 (CRTC1) gene plays a major role in the regulation of energy homeostasis and epigenetic mechanisms may ...

2019

Analysis of deposited layers with deuterium and impurity elements on samples from the divertor of JET with ITER-like wall

Patrick Blanchard, Basil Duval, Ambrogio Fasoli, Yves Martin, Richard Pitts, Olivier Sauter, Henri Weisen, Robin Humphry-Baker, Stefano Coda, Partha Dutta, Marco Wischmeier, Jan Horacek, Vlad Trifa, Yann Camenen, Jonathan Graves, Duccio Testa, Magalie Diane Bassan, Sun Hee Kim, Mikhail Maslov, Javier García Hernández, David Pfefferlé, Fernando Cortes Salazar, Petre Alexandru Arion, Jose Felix Vega Stavro, Lenke Horváth, Hugo Augusto Penedones Fernandes, Stéphanie Prior, Philippe Janson, Daniel Scott Alessi, Matthew Brown, Philippe Jean Buchs, Lorenzo Anton-Louis Talà, Mario Joe Lehmann, Pamela Solange Valdés Undurraga, Michael Oliver Reinke, Jonnathan Cesar Hidalgo Acosta, Wei Tang, Albano António De Abreu E Presa De Castro E Sousa, Lyne Moser, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

Tritium distributions on W-coated divertor tiles used in the third JET ITER-like wall campaign

Patrick Blanchard, Basil Duval, Ambrogio Fasoli, Yves Martin, Richard Pitts, Olivier Sauter, Henri Weisen, Robin Humphry-Baker, Stefano Coda, Partha Dutta, Marco Wischmeier, Vlad Trifa, Yann Camenen, Jonathan Graves, Duccio Testa, Magalie Diane Bassan, Sun Hee Kim, Mikhail Maslov, Javier García Hernández, David Pfefferlé, Fernando Cortes Salazar, Petre Alexandru Arion, Jose Felix Vega Stavro, Lenke Horváth, Hugo Augusto Penedones Fernandes, Stéphanie Prior, Philippe Janson, Daniel Scott Alessi, Matthew Brown, Philippe Jean Buchs, Lorenzo Anton-Louis Talà, Mario Joe Lehmann, Pamela Solange Valdés Undurraga, Michael Oliver Reinke, Jonnathan Cesar Hidalgo Acosta, Wei Tang, Albano António De Abreu E Presa De Castro E Sousa, Lyne Moser, Dalziel Joseph Wilson, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

Population modelling of the He II energy levels in tokamak plasmas: I. Collisional excitation model

Patrick Blanchard, Basil Duval, Ambrogio Fasoli, Yves Martin, Richard Pitts, Olivier Sauter, Henri Weisen, Robin Humphry-Baker, Stefano Coda, Partha Dutta, Marco Wischmeier, Jan Horacek, Vlad Trifa, Yann Camenen, Jonathan Graves, Duccio Testa, Magalie Diane Bassan, Sun Hee Kim, Mikhail Maslov, Javier García Hernández, David Pfefferlé, Fernando Cortes Salazar, Petre Alexandru Arion, Jose Felix Vega Stavro, Lenke Horváth, Hugo Augusto Penedones Fernandes, Stéphanie Prior, Philippe Janson, Daniel Scott Alessi, Matthew Brown, Philippe Jean Buchs, Lorenzo Anton-Louis Talà, Mario Joe Lehmann, Pamela Solange Valdés Undurraga, Michael Oliver Reinke, Jonnathan Cesar Hidalgo Acosta, Wei Tang, Albano António De Abreu E Presa De Castro E Sousa, Lyne Moser, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

A locked mode indicator for disruption prediction on JET and ASDEX upgrade

Patrick Blanchard, Roland Behn, Basil Duval, Ambrogio Fasoli, Timothy Goodman, Yves Martin, Jean-Marc Moret, Richard Pitts, Olivier Sauter, Henri Weisen, Holger Reimerdes, Stefano Coda, Alberto Bottino, Marco Wischmeier, Jan Horacek, Andrea Scarabosio, Hartmut Zohm, Alexander Karpushov, Laurie Porte, Yanis Andrebe, Yann Camenen, Jonathan Graves, Thomas Binderup Jensen, Benoît Labit, Emiliano Fable, Mikhail Maslov, Javier García Hernández, David Pfefferlé, Ben McMillan, Marc Gruber, Christian Gabriel Theiler, Federico Alberto Alfredo Felici, Miguel Filipe Silva Füglister, Dávid Wágner, Attila Bencze, Doohyun Kim, Wouter Vijvers, Hoang Bao Le, Zhouji Huang, Himank Anand, Claudio Marini, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2

Jose Vicente Sanchez Mut

Background: MeCP2-a chromatin-binding protein associated with Rett syndrome-has two main isoforms, MeCP2-E1 and MeCP2-E2, differing in a few N-terminal amino acid residues. Previous studies have shown brain region-specific expression of these isoforms whic ...

2019

Validation of the ICRF antenna coupling code RAPLICASOL against TOPICA and experiments

Patrick Blanchard, Roland Behn, Basil Duval, Timothy Goodman, Pierre Jacquot, Bruno Marchand, Yves Martin, Pascal Morel, Jean-Marc Moret, Richard Pitts, Olivier Sauter, Holger Reimerdes, Stefano Coda, Alberto Bottino, Marco Wischmeier, Jan Horacek, Andrea Scarabosio, Hartmut Zohm, Alexander Karpushov, Laurie Porte, Yanis Andrebe, Yann Camenen, Thomas Binderup Jensen, Duccio Testa, Telmo David Ribeiro Da Costa, Benoît Labit, Emiliano Fable, Patrycja Nowak-Sliwinska, Javier García Hernández, Ben McMillan, Marc Gruber, Christian Gabriel Theiler, Federico Alberto Alfredo Felici, Jose Felix Vega Stavro, Lenke Horváth, Dávid Wágner, Attila Bencze, Thomas Riedl, Lorenzo Anton-Louis Talà, Diego Carnevale, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

Amygdala GluN2B-NMDAR dysfunction is critical in abnormal aggression of neurodevelopmental origin induced by St8sia2 deficiency

Graham Knott, Maria del Carmen Sandi Perez, Olivia Zanoletti, Jocelin Grosse, Elias Georges Gebara, Wei Tang, Alexandre Claude Gustave Bacq, Johannes Gräff, Catherine Maclachlan, Jose Vicente Sanchez Mut, Bianca Ambrogina Silva, Simone Astori

Aggression is frequently observed in neurodevelopmental psychiatric disorders such as schizophrenia, autism, and bipolar disorder. Due to a lack of understanding of its underlying mechanisms, effective treatments for abnormal aggression are still missing. ...

2020

Methods of diagnosis alzheimer's disease

Johannes Gräff, Jose Vicente Sanchez Mut

A method for the diagnosis or prognosis of Alzheimer's disease (AD), includes the steps of placing a sample isolated from a person suspected of having AD onto a substrate labeling the sample to identify at least one epigenetic marker and/or genetic variati ...

2018

PM20D1 is a quantitative trait locus associated with Alzheimer’s disease

Liliane Glauser, Bernard Schneider, Johannes Gräff, Lucie Pauline Dixsaut, Jose Vicente Sanchez Mut, Bianca Ambrogina Silva

2018

Neutron spectroscopy measurements of 14 MeV neutrons at unprecedented energy resolution and implications for deuterium-tritium fusion plasma diagnostics

Patrick Blanchard, Basil Duval, Ambrogio Fasoli, Yves Martin, Richard Pitts, Olivier Sauter, Henri Weisen, Stefano Coda, Marco Wischmeier, Jan Horacek, Vlad Trifa, Yann Camenen, Jonathan Graves, Duccio Testa, Sun Hee Kim, Mikhail Maslov, Javier García Hernández, David Pfefferlé, Petre Alexandru Arion, Jose Felix Vega Stavro, Lenke Horváth, Hugo Augusto Penedones Fernandes, Stéphanie Prior, Philippe Janson, Daniel Scott Alessi, Matthew Brown, Philippe Jean Buchs, Lorenzo Anton-Louis Talà, Mario Joe Lehmann, Pamela Solange Valdés Undurraga, Jonnathan Cesar Hidalgo Acosta, Wei Tang, Albano António De Abreu E Presa De Castro E Sousa, Lyne Moser, Dalziel Joseph Wilson, Justin Robert Young, Jonathan Marc Philippe Faustin, Federico Nespoli, Alexis Gérald Page, , , , , , , , , , , , , , , , , , , , , , ,

14 MeV calibration of JET neutron detectors-phase 1: calibration and characterization of the neutron source

Patrick Blanchard, Basil Duval, Ambrogio Fasoli, Yves Martin, Richard Pitts, Olivier Sauter, Henri Weisen, Robin Humphry-Baker, Stefano Coda, Partha Dutta, Marco Wischmeier, Jan Horacek, Vlad Trifa, Yann Camenen, Jonathan Graves, Duccio Testa, Magalie Diane Bassan, Sun Hee Kim, Mikhail Maslov, Javier García Hernández, David Pfefferlé, Fernando Cortes Salazar, Petre Alexandru Arion, Jose Felix Vega Stavro, Lenke Horváth, Hugo Augusto Penedones Fernandes, Stéphanie Prior, Philippe Janson, Daniel Scott Alessi, Matthew Brown, Philippe Jean Buchs, Lorenzo Anton-Louis Talà, Mario Joe Lehmann, Pamela Solange Valdés Undurraga, Michael Oliver Reinke, Jonnathan Cesar Hidalgo Acosta, Wei Tang, Albano António De Abreu E Presa De Castro E Sousa, Lyne Moser, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

Whole genome grey and white matter DNA methylation profiles in dorsolateral prefrontal cortex

Johannes Gräff, Jose Vicente Sanchez Mut

The brain's neocortex is anatomically organized into grey and white matter, which are mainly composed by neuronal and glial cells, respectively. The neocortex can be further divided in different Brodmann areas according to their cytoarchitectural organizat ...

Wiley-Blackwell2017

Circadian cycle-dependent MeCP2 and brain chromatin changes

Jose Vicente Sanchez Mut

Canadian Science Publishing, Nrc Research Press2017

Input-dependent regulation of excitability controls dendritic maturation in somatosensory thalamocortical neurons

Johannes Gräff, Jose Vicente Sanchez Mut

Input from the sensory organs is required to pattern neurons into topographical maps during development. Dendritic complexity critically determines this patterning process; yet, how signals from the periphery act to control dendritic maturation is unclear. ...

Nature Research2017

Epigenetic Alterations in Alzheimer's Disease

Johannes Gräff, Jose Vicente Sanchez Mut

Alzheimer's disease (AD) is the major cause of dementia in Western societies. It progresses asymptomatically during decades before being belatedly diagnosed when therapeutic strategies have become unviable. Although several genetic alterations have been as ...

Frontiers Research Foundation2015