Publications by Shang-Jung Wu | EPFL Graph Search

Micropreparative Gel Electrophoresis for Purification of Nanoscale Bioconjugates

Vitalijs Zubkovs, Ardemis Anoush Boghossian, Sayyed Hashem Sajjadi, Shang-Jung Wu, Yahya Rabbani

Conventional techniques for purifying macromolecular conjugates often require complex and costly installments that are inaccessible to most laboratories. In this work, we develop a one-step micropreparative method based on a trilayered polyacrylamide gel e ...

2024

Plasmon-induced near-infrared fluorescence enhancement of single-walled carbon nanotubes

Giulia Tagliabue, Amirmostafa Amirjani, Ardemis Anoush Boghossian, Sayyed Hashem Sajjadi, Shang-Jung Wu, Alessandra Antonucci, Theodoros Tsoulos

Single-walled carbon nanotubes (SWCNTs) emit near-infrared (NIR) fluorescence that is ideal for optical sensing. However, the low quantum yields diminish the sensor’s signal-to-noise ratio and limits the penetration depths for in vivo measurements. In this ...

2022

Site-Specific Protein Conjugation onto Fluorescent Single-Walled Carbon Nanotubes

Vitalijs Zubkovs, Ardemis Anoush Boghossian, Shang-Jung Wu, Nils Schürgers

Semiconducting single-walled carbon nanotubes (SWCNTs) are among the few photostable optical emitters that are ideal for sensing, imaging, drug delivery, and monitoring of protein activity. These applications often require strategies for immobilizing prote ...

2020

Establishing a Ternary System for Optical Monitoring of DNA-Protein Interactions with Single-Walled Carbon Nanotubes

Shang-Jung Wu

DNA-protein interactions lie at the crux of life's essential processes. As such, various technologies have been developed to characterize these interactions. The distinct advantages of these technologies can be leveraged to study different facets of these ...

EPFL2020

Analytical Approaches for Monitoring DNA–Protein Interactions

Ardemis Anoush Boghossian, Shang-Jung Wu

DNA–protein interactions play a critical role in cellular regulation. We herein review existing analytical methods for investigating these interactions, highlighting methods such as chromatin immunoprecipitation and yeast-one-hybrid that are used to identi ...

2019

Directed evolution of the optoelectronic properties of synthetic nanomaterials

Ardemis Anoush Boghossian, Shang-Jung Wu, Benjamin Paul Johanès Gabriel Lambert, Alice Judith Gillen

Directed evolution is a powerful approach to tailor protein properties toward new or enhanced functions. Herein, we use directed evolution to engineer the optoelectronic properties of DNA-wrapped single-walled carbon nanotube sensors through DNA mutation. ...

Royal Society of Chemistry2019

Templating colloidal sieves for tuning nanotube surface interactions and optical sensor responses

Daniel Jerôme Siefman, Ardemis Anoush Boghossian, Shang-Jung Wu, Benjamin Paul Johanès Gabriel Lambert, Alice Judith Gillen

Surfactants offer a tunable approach for modulating the exposed surface area of a nanoparticle. They further present a scalable and cost-effective means for suspending single-walled carbon nanotubes (SWCNTs), which have demonstrated practical use as fluore ...

2019

FCC Physics Opportunities: Future Circular Collider Conceptual Design Report Volume 1

Manuel Bauer, Luca Rossi, Thomas Rizzo, François Robert, Jean-Michel Sallese, Pierluigi Bruzzone, Benedikt Moser, Mikhail Chapochnikov, Bernhard Auchmann, Jeffrey Alan Hubbell, Nicolas Andreini, Alban Sublet, Anatole von Lilienfeld, Mathias Oleg Knecht, Yu Bai, Jorg Wenninger, Michele Cascella, Marc-Olivier Sauvain, Tatiana Pieloni, Pablo Marcelo Perez Garcia, Rui Ning Wang, Leonid Rivkin, Hua Zhang, Xavier Buffat, Mingkui Wang, Andrea Wulzer, Martin Vogel, Nathalie Sophie Adeline Serra, Sandra Aumon, Alexandra Sarabando de Carvalho, Roberto Franceschini, Karin Irmgard Löw, Lucia Jimenez Rojo, Jie Gao, Giuseppe Montenero, Marco Drewes, Craig Nowell, Peter Michael Vogel, Shourya Dutta Gupta, Jairo Camilo Quijano Perez, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

Restriction Enzyme Analysis of Double-Stranded DNA on Pristine Single-Walled Carbon Nanotubes

Ardemis Anoush Boghossian, Shang-Jung Wu, Kun-Han Lin, Alice Judith Gillen

2018

Living on the Edge: Re-shaping the Interface of Synthetic Biology and Nanotechnology

Ardemis Anoush Boghossian, Shang-Jung Wu

A new team of researchers at EPFL is taking an 'anti-disciplinary' approach to creating optical devices. These devices take advantage of the synergy in tuning both nano- and bio-material properties, coupling 'the advantages of two growing, albeit tradition ...

Schweizerische Chemische Gesellschaft2016