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Andrea Manfrin

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Related publications (3)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Primate-specific transposable elements shape transcriptional networks during human development

Matthias Lütolf, Didier Trono, Julien Léonard Duc, Sandra Eloise Kjeldsen, Cyril David Son-Tuyên Pulver, Evaristo Jose Planet Letschert, Andrea Manfrin, Julien Paul André Pontis, Delphine Yvette L Grun, Christopher James Playfoot

The human genome harbors more than 4.5 million transposable element (TE)-derived insertions, the result of recurrent waves of invasion and internal propagation. Here they show that TEs belonging to evolutionarily recent subfamilies go on to regulate later ...

Nature Portfolio2022

Engineered signaling centers for the spatially controlled patterning of human pluripotent stem cells

Matthias Lütolf, Felix Naef, Eric Paquet, Yoji Tabata, Ambroise Roger Vuaridel, François Réal Rivest, Andrea Manfrin

Signaling centers, localized groups of cells that secrete morphogens, play a key role in early development and organogenesis by orchestrating spatial cell fate patterning. Here we present a microfluidic approach that exposes human pluripotent stem cell (hP ...

NATURE PUBLISHING GROUP2019

Progress and potential in organoid research

Matthias Lütolf, Andrea Manfrin, Giuliana Rossi

Tissue and organ biology are very challenging to study in mammals, and progress can be hindered, particularly in humans, by sample accessibility and ethical concerns. However, advances in stem cell culture have made it possible to derive in vitro 3D tissue ...

2018