Publications by Maria Carmela Padula

Identifying neurodevelopmental anomalies of white matter microstructure associated with high risk for psychosis in 22q11.2DS

Marie Schaer, Maude Schneider, Maria Carmela Padula, Daniela Maria Zöller

Disruptions of white matter microstructure have been widely reported in schizophrenia. However, the emergence of these alterations during preclinical stages remains poorly understood. 22q11.2 Deletion Syndrome (22q11.2DS) represents a unique model to study ...

SPRINGERNATURE2020

Large-Scale Brain Network Dynamics Provide a Measure of Psychosis and Anxiety in 22q11.2 Deletion Syndrome Daniela

Dimitri Nestor Alice Van De Ville, Marie Schaer, Fikret Isik Karahanoglu, Maria Carmela Padula

BACKGROUND: Prodromal positive psychotic symptoms and anxiety are two strong risk factors for schizophrenia in 22q11.2 deletion syndrome (22q11DS). The analysis of large-scale brain network dynamics during rest is promising to investigate aberrant brain fu ...

ELSEVIER2019

Cortical Dysconnectivity Measured by Structural Covariance Is Associated With the Presence of Psychotic Symptoms in 22q11.2 Deletion Syndrome

Dimitri Nestor Alice Van De Ville, Marie Schaer, Maude Schneider, Maria Carmela Padula

BACKGROUND: 22q11.2 deletion syndrome (22q11DS) is the third-largest known genetic risk factor for the development of psychosis. Dysconnectivity has consistently been implicated in the physiopathology of psychosis. Structural covariance of cortical morphol ...

2018

Cortical morphology development in patients with 22q11.2 deletion syndrome at ultra-high risk of psychosis

Marie Schaer, Maude Schneider, Maria Carmela Padula, Daniela Maria Zöller

Background. Patients with 22q11.2 deletion syndrome (22q11DS) present a high risk of developing psychosis. While clinical and cognitive predictors for the conversion towards a full-blown psychotic disorder are well defined and largely used in practice, neu ...

CAMBRIDGE UNIV PRESS2018

Development of Structural Covariance From Childhood to Adolescence: A Longitudinal Study in 22q11.2DS

Dimitri Nestor Alice Van De Ville, Maude Schneider, Maria Carmela Padula, Daniela Maria Zöller

2018

Psychotic symptoms influence the development of anterior cingulate BOLD variability in 22q11.2 deletion syndrome

Dimitri Nestor Alice Van De Ville, Maude Schneider, Maria Carmela Padula, Daniela Maria Zöller

2018

Disentangling resting-state BOLD variability and PCC functional connectivity in 22q11.2 deletion syndrome

Dimitri Nestor Alice Van De Ville, Marie Schaer, Maria Carmela Padula, Daniela Maria Zöller

Although often ignored in fMRI studies, moment-to-moment variability of blood oxygenation level dependent (BOLD) signals reveals important information about brain function. Indeed, higher brain signal variability has been associated with better cognitive p ...

Elsevier2017