Person

Brian Donal McCabe

Official source

https://people.epfl.ch/brian.mccabe

About this result

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Official source

https://people.epfl.ch/brian.mccabe

About this result

Related units (2)

BMI - Administration

Prof. McCabe Group

Courses taught by this person (3)

BIO-411: Life Sciences engineering: genome to function

Students will acquire fundamental knowledge regarding how genomes can be engineered, how their function can be deciphered, and how their dynamic outputs can be analyzed and modeled.

BIO-510: IGEM

An interdisciplinary EPFL student team will design and build genetic circuits with novel functionalities. Students learn to develop a project and carry it out to completion in a concrete manner. Their

BIO-511: IGEM lab

Related publications (16)

Please note that this is not a complete list of this person’s publications. It includes only semantically relevant works. For a full list, please refer to Infoscience.

Trio preserves motor synapses and prolongs motor ability during aging

Evelyne Ruchti, Greta Limoni, Brian Donal McCabe, Wei Jiao, Soumya Banerjee, Samuel William Vernon

The decline of motor ability is a hallmark feature of aging and is accompanied by degeneration of motor synaptic terminals. Consistent with this, Drosophila motor synapses undergo characteristic age -dependent structural fragmentation co -incident with dim ...

Cell Press2024

Chromosome-level organization of the regulatory genome in the Drosophila nervous system

Christian Iseli, Nicolas Jean Philippe Guex, Julien Dorier, Marion Leleu, Brian Donal McCabe, Rebecca Carolyn Smith

Previous studies have identified topologically associating domains (TADs) as basic units of genome organization. We present evidence of a previously unreported level of genome folding, where distant TAD pairs, megabases apart, interact to form meta-domains ...

2023

A conditional glutamatergic synaptic vesicle marker for Drosophila

Evelyne Ruchti, Brian Donal McCabe

Glutamate is a principal neurotransmitter used extensively by the nervous systems of all vertebrate and invertebrate animals. It is primarily an excitatory neurotransmitter that has been implicated in nervous system development, as well as a myriad of brai ...

OXFORD UNIV PRESS INC2022