Publications by Lester Melie Garcia

A Multicenter Longitudinal MRI Study Assessing LeMan-PV Software Accuracy in the Detection of White Matter Lesions in Multiple Sclerosis Patients

Meritxell Bach Cuadra, Bénédicte Marie Maréchal, Tobias Kober, Cristina Granziera, Po-Jui Lu, Ricardo Alberto Corredor Jerez, Muhamed Barakovic, Lester Melie Garcia

BackgroundDetecting new and enlarged lesions in multiple sclerosis (MS) patients is needed to determine their disease activity. LeMan-PV is a software embedded in the scanner reconstruction system of one vendor, which automatically assesses new and enlarge ...

WILEY2023

An assessment of intra-scanner reproducibility of myelin-sensitive MRI measures

Meritxell Bach Cuadra, Cristina Granziera, Po-Jui Lu, Muhamed Barakovic, Lester Melie Garcia, Francesco La Rosa, Yi Wang

SAGE PUBLICATIONS LTD2021

Effects of eight neuropsychiatric copy number variants on human brain structure

Claudia Modenato, Kuldeep Kumar, Bogdan Draganski, Lester Melie Garcia, Borja Rodriguez Herreros

Many copy number variants (CNVs) confer risk for the same range of neurodevelopmental symptoms and psychiatric conditions including autism and schizophrenia. Yet, to date neuroimaging studies have typically been carried out one mutation at a time, showing ...

SPRINGERNATURE2021

Apolipoprotein E allele 4 effects on Single-Subject Gray Matter Networks in Mild Cognitive Impairment

Lester Melie Garcia

There is evidence that gray matter networks are disrupted in Mild Cognitive Impairment (MCI) and associated with cognitive impairment and faster disease progression. However, it remains unknown how these alterations are related to the presence of Apolipopr ...

ELSEVIER SCI LTD2021

General Principles of Gene Dosage Effects on Brain Structure

Claudia Modenato, Kuldeep Kumar, Bogdan Draganski, Lester Melie Garcia, Borja Rodriguez Herreros

ELSEVIER SCIENCE INC2020

Remodeling of brain morphology in temporal lobe epilepsy

Bogdan Draganski, Lester Melie Garcia

Background Mesial temporal lobe epilepsy (TLE) is one of the most widespread neurological network disorders. Computational anatomy MRI studies demonstrate a robust pattern of cortical volume loss. Most statistical analyses provide information about localiz ...

2020

The Impact Of Copy Number Variants On Brain Morphometry

Claudia Modenato, Kuldeep Kumar, Bogdan Draganski, Lester Melie Garcia, Borja Rodriguez Herreros

ELSEVIER2019

Dopaminergic modulation of cortical motor network lateralization

Michael Herzog, Maya Anna Jastrzebowska, Renaud Marquis, Bogdan Draganski, Lester Melie Garcia

Introduction Unilateral movements are primarily processed in contralateral cortical and subcortical areas and additionally in ipsilateral cerebellum, leading to an asymmetric pattern of neural activation. Decrease of lateralization is characteristic of agi ...

2018