Publications by Aurélian Michel John-Herpin

Antenna-coupled infrared nanospectroscopy of intramolecular vibrational interaction

Felipe Herrera, Hatice Altug, Aurélian Michel John-Herpin

Many photonic and electronic molecular properties, as well as chemical and biochemical reactivities are controlled by fast intramolecular vibrational energy redistribution (IVR). This fundamental ultrafast process limits coherence time in applications from ...

National Academy of Sciences2023

Metasurface-Enhanced Infrared Spectroscopy: An Abundance of Materials and Functionalities

Hatice Altug, Andreas Tittl, Aurélian Michel John-Herpin, Felix Ulrich Richter

Infrared spectroscopy provides unique information on the composition and dynamics of biochemical systems by resolving the characteristic absorption fingerprints of their constituent molecules. Based on this inherent chemical specificity and the capability ...

Wiley-V C H Verlag Gmbh2023

Infrared nanoplasmonic metasurfaces augmented by artificial intelligence for universal biosensing

Aurélian Michel John-Herpin

Nanoplasmonic metasurfaces have shown outstanding light-matter interaction enhancement capabilities, leading to their emergence as powerful platforms for highly sensitive biospectroscopy. Metasurface-enhanced biospectroscopy offers unprecedented opportunit ...

EPFL2022

Infrared Metasurfaces Augmented by Artificial Intelligence for Monitoring Dynamics between All Major Classes of Biomolecules

Hatice Altug, Aurélian Michel John-Herpin, Deepthy Kavungal

IEEE2021

Wafer‐Scale Functional Metasurfaces for Mid‐Infrared Photonics and Biosensing

Hatice Altug, Aurélian Michel John-Herpin, Aleksandrs Leitis, Ming-Lun Tseng

Metasurfaces have emerged as a breakthrough platform for manipulating light at the nanoscale and enabling on-demand optical functionalities for next-generation biosensing, imaging, and light-generating photonic devices. However, translating this technology ...

Wiley2021

Infrared Metasurface Augmented by Deep Learning for Monitoring Dynamics between All Major Classes of Biomolecules

Hatice Altug, Aurélian Michel John-Herpin, Deepthy Kavungal, Lea Katharina Von Mücke

Insights into the fascinating molecular world of biological processes are crucial for understanding diseases, developing diagnostics, and effective therapeutics. These processes are complex as they involve interactions between four major classes of biomole ...

Wiley-V C H Verlag Gmbh2021

Metasurface-Based Molecular Biosensing Aided by Artificial Intelligence

Hatice Altug, Andreas Tittl, Aurélian Michel John-Herpin, Aleksandrs Leitis, Eduardo Romero Arvelo

Molecular spectroscopy provides unique information on the internal structure of biological materials by detecting the characteristic vibrational signatures of their constituent chemical bonds at infrared frequencies. Nanophotonic antennas and metasurfaces ...

Wiley-VCH Verlag GmbH2019

Metasurface‐based molecular biosensing aided by artificial intelligence

Hatice Altug, Andreas Tittl, Aurélian Michel John-Herpin, Aleksandrs Leitis, Eduardo Romero Arvelo

Molecular spectroscopy provides unique information on the internal structure of biological materials by detecting the characteristic vibrational signatures of their constituent chemical bonds at infrared frequencies. Nanophotonic antennas and metasurfaces ...

2019

Self-Similar Multiresonant Nanoantenna Arrays for Sensing from Near- to Mid-Infrared

Hatice Altug, Odeta Limaj, Daniel Rodrigo Lopez, Andreas Tittl, Aurélian Michel John-Herpin

Tailoring nanoscale light concentration and electromagnetic near-field enhancement over a broad spectral range is crucial for many photonics applications such as infrared spectroscopy, photodetection, and light harvesting. So far, broadband light enhanceme ...

2018

Two-Dimensional Label-Free Affinity Analysis of Tumor-Specific CD8 T Cells with a Biomimetic Plasmonic Sensor

Hatice Altug, Xiaokang Li, George Coukos, Maria Soler Aznar, Aurélian Michel John-Herpin

The screening and analysis of T cells functional avidity for specific tumor-associated antigens is crucial for the development of personalized immunotherapies against cancer. The affinity and kinetics of a T cell receptor (TCR) binding to the peptide-major ...

AMER CHEMICAL SOC2018

Quantifying the Limits of Detection of Surface-Enhanced Infrared Spectroscopy with Grating Order-Coupled Nanogap Antennas

Hatice Altug, Andreas Tittl, Aurélian Michel John-Herpin

Infrared spectroscopy is widely used for biomolecular studies, but struggles when investigating minute quantities of analytes due to the mismatch between vibrational cross sections and IR wavelengths. It is therefore beneficial to enhance absorption signal ...

2018

High-Contrast Infrared Absorption Spectroscopy via Mass-Produced Coaxial Zero-Mode Resonators with Sub-10 nm Gaps

Hatice Altug, Aurélian Michel John-Herpin, Sunghwan Kim

We present a wafer-scale array of resonant coaxial nanoapertures as a practical platform for surface-enhanced infrared absorption spectroscopy (SEIRA). Coaxial nanoapertures with sub-10 nm gaps are fabricated via photolithography, atomic layer deposition o ...

American Chemical Society (ACS)2018

Resolving molecule-specific information in dynamic lipid membrane processes with multi-resonant infrared metasurfaces

Hilal Lashuel, Nadine Aït Bouziad, Hatice Altug, Odeta Limaj, Daniel Rodrigo Lopez, Christopher David Kelly, Andreas Tittl, Aurélian Michel John-Herpin

A multitude of biological processes are enabled by complex interactions between lipid membranes and proteins. To understand such dynamic processes, it is crucial to differentiate the constituent biomolecular species and track their individual time evolutio ...

Nature Research2018