Publications by Friedhelm Christoph Hummel

EPFL-Smart-Kitchen-30 Collected data

Solaiman Shokur, Silvestro Micera, Friedhelm Christoph Hummel, Mahdi Hamidi Rad, Alexander Mathis

Understanding behavior requires datasets that capture humans while carrying out complex tasks. The kitchen is an excellent environment for assessing human motor and cognitive function, as many complex actions are naturally exhibited in kitchens from choppi ...

Zenodo2025

Effect of Extrinsic Reward on Motor Plasticity during Skill Learning

Friedhelm Christoph Hummel, Pierre Theopistos Vassiliadis

Human motor skill acquisition is improved by performance feedback, and coupling such feedback with extrinsic reward (such as money) can enhance skill learning. However, the neurophysiology underlying such behavioral effect is unclear. To bridge this gap, w ...

2025

EPFL-Smart-Kitchen-30 Annotations and Poses

Solaiman Shokur, Silvestro Micera, Friedhelm Christoph Hummel, Mahdi Hamidi Rad, Alexander Mathis

Understanding behavior requires datasets that capture humans while carrying out complex tasks. The kitchen is an excellent environment for assessing human motor and cognitive function, as many complex actions are naturally exhibited in kitchens from choppi ...

Zenodo2025

Transcranial Temporal Interference Stimulation (ttis): Pioneering Non-invasive Deep Brain Neuromodulation for Movement Disorders and Beyond

Friedhelm Christoph Hummel

WILEY2025

Impact of spindle-inspired transcranial alternating current stimulation during a nap on sleep-dependent motor memory consolidation in healthy older adults

Manon Chloé Durand-Ruel, Friedhelm Christoph Hummel, Takuya Morishita, Roberto Felipe Salamanca Giron, Maeva Moyne

With the increase in life expectancy and the rapid evolution of daily life technologies, older adults must constantly learn new skills to adapt to society. Sleep reinforces skills acquired during the day and is associated with the occurrence of specific os ...

Oxford University Press (OUP)2025

Beyond the surface: advancing neurorehabilitation with transcranial temporal interference stimulation — clinical applications and future prospects

Friedhelm Christoph Hummel

Ovid Technologies (Wolters Kluwer Health)2025

Improved Spinal Cord FMRI Activation Mapping Using Regularized Hemodynamic Deconvolution

Dimitri Nestor Alice Van De Ville, Friedhelm Christoph Hummel, Estelle Emeline Raffin, Ekansh Sareen

The spinal cord plays a central role in regulating sensorimotor functions through complex neural pathways. However, detailed investigation of these mechanisms remains a developing field. In this study, we propose a multimodal approach combining transcrania ...

IEEE2025

Robotic-Aided Training and Assessment of Upper Limb Muscle Coordination Following Stroke

Claudia Bigoni, Friedhelm Christoph Hummel, Takuya Morishita

Technology-aided interventions and assessments are at the base of personalized motor rehabilitation after stroke. In the AVANCER trial, the effects of a novel personalized neurotech intervention were assessed by using an instrumented Fugl-Meyer (FM) evalua ...

Springer Nature Switzerland2025

Resting-State Cortico-Cerebellar Connectivity Correlates with Post-Stroke Motor Recovery - A Prospective Functional MRI Study

Elena Beanato, Friedhelm Christoph Hummel

Cerebellar functional and structural connectivity are likely related to motor function after stroke. Less is known about motor recovery, which is defined as a gain of function between two time points, and about the involvement of the cerebellum. Fifteen pa ...

2025

Pathway-dependent Brain Stimulation Responses Indicate Motion Processing Integrity After Stroke

Elena Beanato, Michele Bevilacqua, Friedhelm Christoph Hummel, Estelle Emeline Raffin, Sarah Bernardina Zandvliet, Pauline Menoud, Fabienne Windel, Lisa Aïcha Mireille Julie Fleury

Homonymous hemianopia (HH), a common visual impairment resulting from occipital lobe lesions, affects a significant number of stroke survivors. Intensive perceptual training can foster recovery, possibly by enhancing surviving visual pathways. This study e ...

OXFORD UNIV PRESS2025

Brain Oscillatory Modes as a Proxy of Stroke Recovery

Dimitri Nestor Alice Van De Ville, Olaf Blanke, Philip Egger, Sylvain Jean-François Harquel, Silvestro Micera, Nathalie Heidi Meyer, Elena Beanato, Julia Brügger, Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Philipp Johannes Koch, Giorgia Giulia Evangelista, Andéol Geoffroy Cadic-Melchior, Pauline Menoud, Lisa Aïcha Mireille Julie Fleury

Background Stroke is the leading cause of long-term disability, making the search for successful rehabilitation treatment one of the most important public health issues. A better understanding of the neural mechanisms underlying impairment and recovery is ...

SAGE Publications2025

Precision non-invasive brain stimulation: an in silico pipeline for personalized control of brain dynamics

Elena Beanato, Friedhelm Christoph Hummel

Objective. Non-invasive brain stimulation (NIBS) offers therapeutic benefits for various brain disorders. Personalization may enhance these benefits by optimizing stimulation parameters for individual subjects. Approach. We present a computational pipeline ...

2025

Noninvasive modulation of the hippocampal-entorhinal complex during spatial navigation in humans

Olaf Blanke, Elena Beanato, Hyukjun Moon, Esra Neufeld, Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Baptiste Gauthier, Traian Popa, Pierre Theopistos Vassiliadis, Emanuela De Falco, Pauline Menoud, Fabienne Windel

Because of the depth of the hippocampal-entorhinal complex (HC-EC) in the brain, understanding of its role in spatial navigation via neuromodulation was limited in humans. Here, we aimed to better elucidate this relationship in healthy volunteers, using tr ...

American Association for the Advancement of Science (AAAS)2024

MEP and TEP features variability: is it just the brain-state?

Sylvain Jean-François Harquel, Michele Bevilacqua, Claudia Bigoni, Friedhelm Christoph Hummel, Estelle Emeline Raffin, Andéol Geoffroy Cadic-Melchior

Objective. The literature investigating the effects of alpha oscillations on corticospinal excitability is divergent. We believe inconsistency in the findings may arise, among others, from the electroencephalography (EEG) processing for brain-state determi ...

Iop Publishing Ltd2024

Non-invasive stimulation of the human striatum disrupts reinforcement learning of motor skills

Elena Beanato, Esra Neufeld, Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Traian Popa, Pierre Theopistos Vassiliadis, Julie Duqué, Fabienne Windel

Reinforcement feedback can improve motor learning, but the underlying brain mechanisms remain underexplored. In particular, the causal contribution of specific patterns of oscillatory activity within the human striatum is unknown. To address this question, ...

Nature Portfolio2024

Efficacy and safety of transcranial direct current stimulation to the ipsilesional motor cortex in subacute stroke (NETS): a multicenter, randomized, double-blind, placebo-controlled trial

Friedhelm Christoph Hummel

Background Each year, five million people are left disabled after stroke. Upper -extremity (UE) dysfunction is a leading problem. Neuroplasticity can be enhanced by non-invasive brain stimulation (NIBS) but evidence from large, randomized multicenter trial ...

Elsevier2024

Native learning ability and not age determines the effects of brain stimulation

Pablo Maceira Elvira, Friedhelm Christoph Hummel, Anne-Christine Schmid, Andéol Geoffroy Cadic-Melchior, Traian Popa

Healthy aging often entails a decline in cognitive and motor functions, affecting independence and quality of life in older adults. Brain stimulation shows potential to enhance these functions, but studies show variable effects. Previous studies have tried ...

2024

Physiology-inspired bifocal fronto-parietal tACS for working memory enhancement

Sylvain Jean-François Harquel, Pablo Maceira Elvira, Friedhelm Christoph Hummel, Traian Popa

Aging populations face significant cognitive challenges, particularly in working memory (WM). Transcranial alternating current stimulation (tACS) offer promising avenues for cognitive enhancement, especially when inspired by brain physiology. This study (N ...

2024

Non-invasive deep brain stimulation: interventional targeting of deep brain areas in neurological disorders

Friedhelm Christoph Hummel

Recently developed non-invasive deep brain stimulation methods have sufficient focal specificity to target deep brain structures. These techniques show particular promise as treatment strategies for neuropsychiatric disorders in which deep brain structures ...

NATURE PORTFOLIO2024

Single session cross-frequency bifocal tACS modulates visual motion network activity in young healthy population and stroke patients

Michele Bevilacqua, Friedhelm Christoph Hummel, Estelle Emeline Raffin, Roberto Felipe Salamanca Giron, Sarah Bernardina Zandvliet, Pauline Menoud, Fabienne Windel, Lisa Aïcha Mireille Julie Fleury

Objective: This study investigates the impact of single-session, cross-frequency (Alpha-Gamma) bifocal transcranial alternating current stimulation (cf-tACS) to the cortical visual motion network on inter-areal coupling between the primary visual cortex (V ...

2024