Sina Rüeger

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Related publications (6)

Genome-to-genome analysis reveals associations between human and mycobacterial genetic variation in tuberculosis patients from Tanzania

Jacques Fellay, Dylan Lawless, Olivier Noël Marie Naret, Sina Rüeger, Zhi Ming Xu

The risk and prognosis of tuberculosis (TB) are influenced by a complex interplay between human and bacterial genetic factors. While previous genomic studies have largely examined human and bacterial genomes separately, we adopted an integrated approach to ...

Springer Science and Business Media LLC2025

Using population-specific add-on polymorphisms to improve genotype imputation in underrepresented populations

Jacques Fellay, Sina Rüeger, Zhi Ming Xu

Genome-wide association studies rely on the statistical inference of untyped variants, called imputation, to increase the coverage of genotyping arrays. However, the results are often suboptimal in populations underrepresented in existing reference panels ...

Public Library Science2022

The influence of human genetic variation on Epstein–Barr virus sequence diversity

Jacques Fellay, Christian Hammer, Dylan Lawless, Olivier Noël Marie Naret, Sina Rüeger

Epstein–Barr virus (EBV) is one of the most common viruses latently infecting humans. Little is known about the impact of human genetic variation on the large inter-individual differences observed in response to EBV infection. To search for a potential imp ...

Nature Research2021

Genome-to-genome analysis identifies an Asian-specific variant in the gene encoding NTCP that leads to specific HBV escape mutations during chronic infection

Jacques Fellay, Sina Rüeger, Zhi Ming Xu

SPRINGERNATURE2020

Weight Loss Directly Influences Intermediate-Term Remission of Diabetes Mellitus After Bariatric Surgery: A Retrospective Case-Control Study

Sina Rüeger

Purpose Roux en Y gastric bypass surgery (RYGB) is an effective therapy for patients with severe obesity. It induces both significant weight loss and rapid improvements of metabolic complications. This study was undertaken to better define the direct role ...

2020

Transcriptome-wide causal analyses reveals sex-specific biomarkers for complex human traits

Sina Rüeger

NATURE PUBLISHING GROUP2019

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