Publications by Laura Emmanuelle Kowalczuk

Adaptive Optics-Transscleral Flood Illumination Imaging of Retinal Pigment Epithelium in Dry Age-Related Macular Degeneration

Christophe Moser, Laura Emmanuelle Kowalczuk

Adaptive optics-transscleral flood illumination (AO-TFI) is a novel imaging technique with potential for detecting retinal pigment epithelium (RPE) changes in dry age-related macular degeneration (AMD). This single-center prospective study evaluated its ab ...

MDPI AG2025

High-resolution adaptive optics-trans-scleral flood illumination (AO-TFI) imaging of retinal pigment epithelium (RPE) in central serous chorioretinopathy (CSCR)

Christophe Moser, Laura Emmanuelle Kowalczuk

This study aims to correlate adaptive optics-transscleral flood illumination (AO-TFI) images of the retinal pigment epithelium (RPE) in central serous chorioretinopathy (CSCR) with standard clinical images and compare cell morphological features with those ...

Nature Research2024

Transscleral Optical Imaging (TOI) in Central Serous Chorioretinopathy - A novel imaging tool in retinal pigment epithelium visualization

Christophe Moser, Laura Emmanuelle Kowalczuk

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2022

In Vivo Retinal Pigment Epithelium Imaging using Transscleral Optical Imaging in Healthy Eyes

Christophe Moser, Mathieu Künzi, Timothé Laforest, Laura Emmanuelle Kowalczuk

Objective: To image healthy retinal pigment epithelial (RPE) cells in vivo using Transscleral OPtical Imaging (TOPI) and to analyze statistics of RPE cell features as a function of age, axial length (AL), and eccentricity. Design: Single-center, explorator ...

ELSEVIER2022

Transscleral optical imaging in non-neovascular age-related macular degeneration

Christophe Moser, Laura Emmanuelle Kowalczuk

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2022

Human retinal pigment epithelium cells can be imaged in vivo with a novel adaptive optics camera using transscleral illumination

Christophe Moser, Mathieu Künzi, Timothé Laforest, Laura Emmanuelle Kowalczuk

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2022

Transscleral optical phase imaging in non-neovascular age-related macular degeneration

Christophe Moser, Mathieu Künzi, Timothé Laforest, Laura Emmanuelle Kowalczuk

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2021

Fully automated detection, segmentation, and analysis of in vivo RPE single cells

Christophe Moser, Timothé Laforest, Florentino Luciano Caetano Dos Santos, Laura Emmanuelle Kowalczuk

Objective To develop a fully automated method of retinal pigmented epithelium (RPE) cells detection, segmentation and analysis based on in vivo cellular resolution images obtained with the transscleral optical phase imaging method (TOPI). Methods Fourteen ...

NATURE PUBLISHING GROUP2021

Transscleral Optical Phase Imaging of healthy human Retinal Pigment Epithelium

Christophe Moser, Mathieu Künzi, Timothé Laforest, Laura Emmanuelle Kowalczuk

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2021

Transscleral optical phase imaging of the human retina

Christophe Moser, Dino Carpentras, Timothé Laforest, Laura Emmanuelle Kowalczuk

In vivo observation of the human retina at the cellular level is crucial to detect the first signs of retinal diseases and properly treat them. Despite the phenomenal advances in adaptive optics systems, clinical imaging of many retinal cells is still elus ...

Nature Publishing Group2020

Optical phase contrast imaging of human retinal cells by changing the tissue refractive index

Christophe Moser, Mathieu Künzi, Timothé Laforest, Laura Emmanuelle Kowalczuk

Purpose : Based on oblique partially coherent illumination of transparent samples, we developed a simple custom Optical Phase Imaging (OPI) microscope providing a label-free, semi-quantitative phase contrast imaging. The aim of this study was to explore th ...

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2020

Laura Emmanuelle Kowalczuk

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Adaptive Optics-Transscleral Flood Illumination Imaging of Retinal Pigment Epithelium in Dry Age-Related Macular Degeneration

High-resolution adaptive optics-trans-scleral flood illumination (AO-TFI) imaging of retinal pigment epithelium (RPE) in central serous chorioretinopathy (CSCR)

Transscleral Optical Imaging (TOI) in Central Serous Chorioretinopathy - A novel imaging tool in retinal pigment epithelium visualization

In Vivo Retinal Pigment Epithelium Imaging using Transscleral Optical Imaging in Healthy Eyes

Transscleral optical imaging in non-neovascular age-related macular degeneration

Human retinal pigment epithelium cells can be imaged in vivo with a novel adaptive optics camera using transscleral illumination

Transscleral optical phase imaging in non-neovascular age-related macular degeneration

Fully automated detection, segmentation, and analysis of in vivo RPE single cells

Transscleral Optical Phase Imaging of healthy human Retinal Pigment Epithelium

Transscleral optical phase imaging of the human retina

Optical phase contrast imaging of human retinal cells by changing the tissue refractive index

Transscleral optical phase imaging (TOPI) of human retinal pigment epithelium

Involvement of the PlGF/VEGFR1 pathway in diabetes and type 1 retinal telangiectasia

CSCR and the identification of new molecular mineralocorticoid targets in retinal pigment epithelium cells

Phase imaging of retinal cells for clinical studies and diagnosis