Publication

Mechanical control of fluids in micro-analytical devices

Hubert Girault, Joël Stéphane Rossier, Joël Rossier, Xiaoxia Bai
2006
Patents

Abstract

An apparatus for manipulating fluid samples comprises a micro-chip device having first and second covered channels, each channel having openings at both ends. The channels intersect to form a common intersection. Three of the openings of the channels are connected to a multi-port valve to control pressure in the device.

Official source

https://infoscience.epfl.ch/entities/publication/089e34c3-cc54-4350-afb7-edaa4d16c09c

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Hubert Girault, Joël Stéphane Rossier, Joël Rossier, Xiaoxia Bai
2006
Patents

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/089e34c3-cc54-4350-afb7-edaa4d16c09c

About this result

Related concepts (14)

Microfluidics

Microfluidics refers to a system that manipulates a small amount of fluids ((10−9 to 10−18 liters) using small channels with sizes ten to hundreds micrometres. It is a multidisciplinary field that involves molecular analysis, biodefence, molecular biology, and microelectronics. It has practical applications in the design of systems that process low volumes of fluids to achieve multiplexing, automation, and high-throughput screening.

Sodium channel

Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's membrane. They belong to the superfamily of cation channels. They are classified into 2 types: In excitable cells such as neurons, myocytes, and certain types of glia, sodium channels are responsible for the rising phase of action potentials. These channels go through three different states called resting, active and inactive states.

Potassium channel

Potassium channels are the most widely distributed type of ion channel found in virtually all organisms. They form potassium-selective pores that span cell membranes. Potassium channels are found in most cell types and control a wide variety of cell functions. Potassium channels function to conduct potassium ions down their electrochemical gradient, doing so both rapidly (up to the diffusion rate of K+ ions in bulk water) and selectively (excluding, most notably, sodium despite the sub-angstrom difference in ionic radius).

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