Publication

Synthesis of monosaccharides and analogues - Part three: Monosaccharides from simple achiral unsaturated compounds

Pierre Vogel, Inmaculada Robina
2007
Journal Articles

Abstract

Nowadays any natural and non-natural monosaccharide can be prepared pure in both enantiomeric forms starting from inexpensive starting materials. Depending on the target, pure chemical procedures relying upon asymmetric catalysis using either metallic or pure organic catalysts can be applied successfully, alone or in combination with chemoenzymatic methods.

Official source

https://infoscience.epfl.ch/entities/publication/0b87dc4b-0634-4dd7-8eee-7e1754d8f160

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Pierre Vogel, Inmaculada Robina
2007
Journal Articles

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/0b87dc4b-0634-4dd7-8eee-7e1754d8f160

About this result

Related concepts (18)

Kinetic resolution

In organic chemistry, kinetic resolution is a means of differentiating two enantiomers in a racemic mixture. In kinetic resolution, two enantiomers react with different reaction rates in a chemical reaction with a chiral catalyst or reagent, resulting in an enantioenriched sample of the less reactive enantiomer. As opposed to chiral resolution, kinetic resolution does not rely on different physical properties of diastereomeric products, but rather on the different chemical properties of the racemic starting materials.

Enantioselective synthesis

Enantioselective synthesis, also called asymmetric synthesis, is a form of chemical synthesis. It is defined by IUPAC as "a chemical reaction (or reaction sequence) in which one or more new elements of chirality are formed in a substrate molecule and which produces the stereoisomeric (enantiomeric or diastereomeric) products in unequal amounts." Put more simply: it is the synthesis of a compound by a method that favors the formation of a specific enantiomer or diastereomer.

Organocatalysis

In organic chemistry, organocatalysis is a form of catalysis in which the rate of a chemical reaction is increased by an organic catalyst. This "organocatalyst" consists of carbon, hydrogen, sulfur and other nonmetal elements found in organic compounds. Because of their similarity in composition and description, they are often mistaken as a misnomer for enzymes due to their comparable effects on reaction rates and forms of catalysis involved.

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