Publication

Multi-panel, on-single-chip Memristive Biosensing

Giovanni De Micheli, Sandro Carrara, Danilo Demarchi, Ioulia Tzouvadaki, Abuduwaili Tuoheti
2019
Journal Articles

Abstract

Memristive biosensors have demonstrated excellent capabilities for ultrasensitive bio-detection. In the present work, memristive biosensing chips are designed, fabricated and implemented in a for the first time presented multi-panel on-chip detection for discrete sensing of a target molecule through separate functionalization of individual devices on the same chip. The biosensing scheme is validated by means of labeled (i.e. fluorescence) and label-free (i.e. electrical) characterization methods. This novel memristive multi-panel sensing paradigm paves the way for fast and ultrasensitive PoC (point-of-care) devices allowing the detection of specific targets in complex matrixes where non-specific molecules are present as well, and opening great potential for the application of memristive phenomena in multiplexed ultrasensitive bio-detection and theranostics.

Official source

https://infoscience.epfl.ch/entities/publication/0f88ecd2-9687-40d3-b0bc-a1f27003f47c

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Giovanni De Micheli, Sandro Carrara, Danilo Demarchi, Ioulia Tzouvadaki, Abuduwaili Tuoheti
2019
Journal Articles

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/0f88ecd2-9687-40d3-b0bc-a1f27003f47c

About this result

Related concepts (15)

Symmetric matrix

In linear algebra, a symmetric matrix is a square matrix that is equal to its transpose. Formally, Because equal matrices have equal dimensions, only square matrices can be symmetric. The entries of a symmetric matrix are symmetric with respect to the main diagonal. So if denotes the entry in the th row and th column then for all indices and Every square diagonal matrix is symmetric, since all off-diagonal elements are zero. Similarly in characteristic different from 2, each diagonal element of a skew-symmetric matrix must be zero, since each is its own negative.

Matrix (mathematics)

In mathematics, a matrix (plural matrices) is a rectangular array or table of numbers, symbols, or expressions, arranged in rows and columns, which is used to represent a mathematical object or a property of such an object. For example, is a matrix with two rows and three columns. This is often referred to as a "two by three matrix", a " matrix", or a matrix of dimension . Without further specifications, matrices represent linear maps, and allow explicit computations in linear algebra.

Complex conjugate

In mathematics, the complex conjugate of a complex number is the number with an equal real part and an imaginary part equal in magnitude but opposite in sign. That is, if and are real numbers then the complex conjugate of is The complex conjugate of is often denoted as or . In polar form, if and are real numbers then the conjugate of is This can be shown using Euler's formula. The product of a complex number and its conjugate is a real number: (or in polar coordinates).

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