Publications related to Human thermal perception and time of day: A review

Statistical physics of periodic biological processes

Earth rotation around its axis imposes a 24-hour rhythmicity to all life on the planet. Rather than passively responding to these periodic changes, nature has given us an internal timekeeper, the circadian clock, to anticipate to our advantage the fluctuat ...

EPFL2023

Uncovering personalized glucose responses and circadian rhythms from multiple wearable biosensors with Bayesian dynamical modeling

Felix Naef, Nicholas Edward Phillips

Wearable biosensors and smartphone applications can measure physiological variables over multiple days in free-living conditions. We measure food and drink ingestion, glucose dynamics, physical activity, heart rate (HR), and heart rate variability (HRV) in ...

CELL PRESS2023

The circadian clock time tunes axonal regeneration

Thomas Haynes Hutson

Nerve injuries cause permanent neurological disability due to limited axonal regeneration. Injury-dependent and-independent mechanisms have provided important insight into neuronal regeneration, however, common denominators underpinning regeneration remain ...

Cell Press2023

Sex-dimorphic and age-dependent organization of 24-hour gene expression rhythms in humans

Felix Naef, Cédric Gobet, Lorenzo Talamanca

The circadian clock modulates human physiology. However, the organization of tissue-specific gene expression rhythms and how these depend on age and sex is not defined in humans. We combined data from the Genotype-Tissue Expression (GTEx) project with an a ...

American Association for the Advancement of Science2023

Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior

Cédric Gobet, Sylviane Métairon, Frédéric Bruno Martin Gachon, Benjamin Dieter Weger

The synchronization of circadian clock depends on a central pacemaker located in the suprachiasmatic nuclei. However, the potential feedback of peripheral signals on the central clock remains poorly characterized. To explore whether peripheral organ circad ...

AMER ASSOC ADVANCEMENT SCIENCE2023

Reduced order models for coupled systems

Niccolo' Discacciati

Efficient numerical simulations of coupled multi-component systems can be particularly challenging. This is mostly due to the complexity of their solutions, as mutual interactions may cause emergent behaviors, including synchronization and instabilities. V ...

EPFL2023

Preserving suspended structures with light façades (1960-1980). Architectural study and retrofitting proposals

Giuseppe Galbiati

Nowadays, the energy efficiency of the existing building stock is internationally accepted as a topical issue. Energy retrofitting is encouraged, improving the thermal performances of buildings, but often altering the historical image of our cities. Attent ...

EPFL2023

Assessment of Monitoring Strategies for Inhalation Exposure and Occupancy in Office Environments

Seoyeon Yun

Given people's significant time spent indoors, ensuring good indoor air quality (IAQ) is essential because it significantly influences occupants' health and productivity. Office buildings consume about 50% of commercial building energy and 18% of total bui ...

EPFL2023

Modeling local thermal responses of individuals: Validation of advanced human thermo-physiology models

Dolaana Khovalyg, Mohamad Rida

Human thermo-physiology models (HTPM) are useful tools to assess dynamic and non-uniform human thermal states. However, they are developed based on the physiological data of an average person. In this paper, we present a detailed evaluation of two sophisti ...

2023

DIET Controller: Dynamic Indoor Environment using Deep Reinforcement Learning

Arnab Chatterjee

Heating, Ventilation, and Air Conditioning (HVAC) Systems utilize much energy, accounting for 40% of total building energy use. The temperatures in buildings are commonly held within narrow limits, leading to higher energy use. Measurements from office bui ...

EPFL2023

A modelling framework for modern heritage buildings energy simulation

Franz Graf, Giulia Marino, Giuseppe Galbiati

The latest European polices highlight the urgent need to rehabilitate the existing building stock, responsible for 40 % of the EU's total energy consumption. In this process, a key role is played by thermal simulations, assessing the effective energy perfo ...

Elsevier2023

Taking a step back from glass towers facades to make them compatible with the 2050 targets

Bernard Paule, Sergi Aguacil Moreno

Skyscrapers or glass towers are an extremely common model throughout the world. In the current context of climate change and resource depletion, we need to develop new postures towards these objects, especially for existing buildings that are becoming obso ...

2023

PePTM: An Efficient and Accurate Personalized P2P Learning Algorithm for Home Thermal Modeling

Rachid Guerraoui, Omid Ardakanian, Alexandre David Olivier Maurer

Nowadays, the integration of home automation systems with smart thermostats is a common trend, designed to enhance resident comfort and conserve energy. The introduction of smart thermostats that can run machine learning algorithms has opened the door for ...

MDPI2023

Efficacy of temporal and spatial abstraction for training accurate machine learning models: A case study in smart thermostats

Rachid Guerraoui, Omid Ardakanian, Alexandre David Olivier Maurer

Smart thermostats are increasingly popular in homes and buildings as they improve occupant comfort, lower energy use in heating and cooling systems, and reduce utility bills by automatically adjusting room temperature according to measurements of their bui ...

ELSEVIER SCIENCE SA2023

Optimized office lighting advances melatonin phase and peripheral heat loss prior bedtime

Jean-Louis Scartezzini, Mirjam Münch, Lenka Maierova, Marta Benedetti

Improving indoor lighting conditions at the workplace has the potential to support proper circadian entrainment of hormonal rhythms, sleep, and well-being. We tested the effects of optimized dynamic daylight and electric lighting on circadian phase of mela ...

Nature Research2022

A simulation tool for building and lighting design considering ipRGC-influenced light responses

Marilyne Andersen, Clotilde Marie A Pierson, Myrta Gkaintatzi-Masouti

The ipRGCs in the human eye mediate several effects on people, such as alertness and circadian rhythms. The spectral, temporal and spatial characteristics of light influence the magnitude of these effects. To facilitate the anticipation of the ipRGC-influe ...

2022

Preliminary evidence that daily light exposure enhances the antibody response to influenza vaccination in patients with dementia

Jean-Louis Scartezzini

Enhancing lighting conditions in institutions for individuals with dementia improves their sleep, circadian rhythms and well-being. Here, we report first findings that exposure to brighter light during daytime may support the immune response to the annual ...

ELSEVIER2022

Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets

Howard Riezman, Jonathan Paz Montoya

Recent evidence suggests that circadian clocks ensure temporal orchestration of lipid homeostasis and play a role in pathophysiology of metabolic diseases in humans, including type 2 diabetes (T2D). Nevertheless, circadian regulation of lipid metabolism in ...

PUBLIC LIBRARY SCIENCE2022

Comprehensive analysis of the circadian nuclear and cytoplasmic transcriptome in mouse liver

Felix Naef, Cédric Gobet, Clémence Yumie Syloun Hurni, Benjamin Dieter Weger

In eukaryotes, RNA is synthesised in the nucleus, spliced, and exported to the cytoplasm where it is translated and finally degraded. Any of these steps could be subject to temporal regulation during the circadian cycle, resulting in daily fluctuations of ...

PUBLIC LIBRARY SCIENCE2022

Interindividual variability of human thermoregulation: Toward personalized ergonomics of the indoor thermal environment

Dolaana Khovalyg

Objective The study was undertaken to show the magnitude of interindividual differences in energy expenditure (i.e., heat production) under normal living conditions with the aim of providing physiological evidence to support the advancement of a personaliz ...

WILEY2022