Publication

On the origin of the boson peak in globular proteins

Paolo De Los Rios, Francesco Piazza
2007
Journal Articles

Abstract

We study the boson peak phenomenology experimentally observed in globular proteins by means of elastic network models. These models are suitable for an analytic treatment in the framework of Euclidean random matrix theory, whose predictions can be numerically tested oil real protein structures. We find that the emergence of the boson peak is strictly related to an intrinsic mechanical instability of the protein. in close similarity to what is thought to happen in glasses. The biological implications, Of this Conclusion are also discussed by focusing Oil a representation case study.

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https://infoscience.epfl.ch/entities/publication/2bf6d104-edbd-45d7-b89d-69aa7c0628b2

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Paolo De Los Rios, Francesco Piazza
2007
Journal Articles

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/2bf6d104-edbd-45d7-b89d-69aa7c0628b2

About this result

Related concepts (21)

Globular protein

In biochemistry, globular proteins or spheroproteins are spherical ("globe-like") proteins and are one of the common protein types (the others being fibrous, disordered and membrane proteins). Globular proteins are somewhat water-soluble (forming colloids in water), unlike the fibrous or membrane proteins. There are multiple fold classes of globular proteins, since there are many different architectures that can fold into a roughly spherical shape. The term globin can refer more specifically to proteins including the globin fold.

Representation theory

Representation theory is a branch of mathematics that studies abstract algebraic structures by representing their elements as linear transformations of vector spaces, and studies modules over these abstract algebraic structures. In essence, a representation makes an abstract algebraic object more concrete by describing its elements by matrices and their algebraic operations (for example, matrix addition, matrix multiplication).

Group representation

In the mathematical field of representation theory, group representations describe abstract groups in terms of bijective linear transformations of a vector space to itself (i.e. vector space automorphisms); in particular, they can be used to represent group elements as invertible matrices so that the group operation can be represented by matrix multiplication. In chemistry, a group representation can relate mathematical group elements to symmetric rotations and reflections of molecules.

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