Publication

Integrated Biosensors for Personalized Medicine

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Cristina Boero, Camilla Baj-Rossi
2012
Conference Papers

Abstract

Biosensors are heterogenous devices, incorporating biological struc- tures combined with electronics, optical or other readout systems. They have been developed for detecting different biomolecules and/or pathogens and represent a key technology for advanced and point- of-care diagnostics as well as patient monitoring. In this paper we present a systematic classification of biosensors described in litera- ture, particularly focusing on nanotechnology-based sensing. Then, we present our approach to develop electrochemical biosensors for measuring metabolites and anticancer drugs, based on a platform for multiple target detection. This platform is modular and achieves a clear separation between the chemical and the electrical compo- nents, thus easing design and manufacturing. It shows superior per- formance thanks to the excellent properties of electron transfer and selectivity showed by enzymes immobilized on carbon nanotubes.

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https://infoscience.epfl.ch/entities/publication/2db9410b-b3c8-4208-a481-4fcb4f571749

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Giovanni De Micheli, Sandro Carrara, Irene Taurino, Cristina Boero, Camilla Baj-Rossi
2012
Conference Papers

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/2db9410b-b3c8-4208-a481-4fcb4f571749

About this result

Related concepts (17)

Biosensor

A biosensor is an analytical device, used for the detection of a chemical substance, that combines a biological component with a physicochemical detector. The sensitive biological element, e.g. tissue, microorganisms, organelles, cell receptors, enzymes, antibodies, nucleic acids, etc., is a biologically derived material or biomimetic component that interacts with, binds with, or recognizes the analyte under study. The biologically sensitive elements can also be created by biological engineering.

Key (cryptography)

A key in cryptography is a piece of information, usually a string of numbers or letters that are stored in a file, which, when processed through a cryptographic algorithm, can encode or decode cryptographic data. Based on the used method, the key can be different sizes and varieties, but in all cases, the strength of the encryption relies on the security of the key being maintained. A key's security strength is dependent on its algorithm, the size of the key, the generation of the key, and the process of key exchange.

Nanotechnology

Nanotechnology, often shortened to nanotech, is the use of matter on atomic, molecular, and supramolecular scales for industrial purposes. The earliest, widespread description of nanotechnology referred to the particular technological goal of precisely manipulating atoms and molecules for fabrication of macroscale products, also now referred to as molecular nanotechnology. A more generalized description of nanotechnology was subsequently established by the National Nanotechnology Initiative, which defined nanotechnology as the manipulation of matter with at least one dimension sized from 1 to 100 nanometers (nm).

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