Physical quantityA physical quantity (or simply quantity) is a property of a material or system that can be quantified by measurement. A physical quantity can be expressed as a value, which is the algebraic multiplication of a numerical value and a unit of measurement. For example, the physical quantity mass, symbol m, can be quantified as m=n kg, where n is the numerical value and kg is the unit symbol (for kilogram). Following ISO 80000-1, any value or magnitude of a physical quantity is expressed as a comparison to a unit of that quantity.
Peptide synthesisIn organic chemistry, peptide synthesis is the production of peptides, compounds where multiple amino acids are linked via amide bonds, also known as peptide bonds. Peptides are chemically synthesized by the condensation reaction of the carboxyl group of one amino acid to the amino group of another. Protecting group strategies are usually necessary to prevent undesirable side reactions with the various amino acid side chains. Chemical peptide synthesis most commonly starts at the carboxyl end of the peptide (C-terminus), and proceeds toward the amino-terminus (N-terminus).
Tower blockA tower block, high-rise, apartment tower, residential tower, apartment block, block of flats, or office tower is a tall building, as opposed to a low-rise building and is defined differently in terms of height depending on the jurisdiction. It is used as a residential, office building, or other functions including hotel, retail, or with multiple purposes combined. Residential high-rise buildings are also known in some varieties of English, such as British English, as tower blocks and may be referred to as MDUs, standing for multi-dwelling units.
International Prototype of the KilogramThe International Prototype of the Kilogram (referred to by metrologists as the IPK or Le Grand K; sometimes called the ur-kilogram, or urkilogram, particularly by German-language authors writing in English:30) is an object whose mass was used to define the kilogram from 1889, when it replaced the Kilogramme des Archives, until 2019, when it was replaced by a new definition of the kilogram based entirely on physical constants. During that time, the IPK and its duplicates were used to calibrate all other kilogram mass standards on Earth.
MKS system of unitsThe MKS system of units is a physical system of measurement that uses the metre, kilogram, and second (MKS) as base units. The modern International System of Units (SI) was originally created as a formalization of the MKS system, and although the SI has been redefined several times since then and is now based entirely on fundamental physical constants, it still closely approximates the original MKS system for most practical purposes. By the mid-19th century, there was a demand by scientists to define a coherent system of units.
International System of UnitsThe International System of Units, internationally known by the abbreviation SI (for Système International), is the modern form of the metric system and the world's most widely used system of measurement. Established and maintained by the General Conference on Weights and Measures (CGPM), it is the only system of measurement with an official status in nearly every country in the world, employed in science, technology, industry, and everyday commerce.
Chirality (chemistry)In chemistry, a molecule or ion is called chiral (ˈkaɪrəl) if it cannot be superposed on its by any combination of rotations, translations, and some conformational changes. This geometric property is called chirality (kaɪˈrælɪti). The terms are derived from Ancient Greek χείρ (cheir) 'hand'; which is the canonical example of an object with this property. A chiral molecule or ion exists in two stereoisomers that are mirror images of each other, called enantiomers; they are often distinguished as either "right-handed" or "left-handed" by their absolute configuration or some other criterion.
Metric systemThe metric system is a system of measurement that succeeded the decimalised system based on the metre, which had been introduced in France in the 1790s. The historical development of these systems culminated in the definition of the International System of Units (SI) in the mid-20th century, under the oversight of an international standards body. Adopting the metric system is known as metrication. The historical evolution of metric systems has resulted in the recognition of several principles.
Chiral resolutionChiral resolution, or enantiomeric resolution, is a process in stereochemistry for the separation of racemic compounds into their enantiomers. It is an important tool in the production of optically active compounds, including drugs. Another term with the same meaning is optical resolution. The use of chiral resolution to obtain enantiomerically pure compounds has the disadvantage of necessarily discarding at least half of the starting racemic mixture. Asymmetric synthesis of one of the enantiomers is one means of avoiding this waste.
ApartmentAn apartment (American English), flat (British English, Indian English, South African English), or unit (Australian English) is a self-contained housing unit (a type of residential real estate) that occupies part of a building, generally on a single storey. There are many names for these overall buildings, see below. The housing tenure of apartments also varies considerably, from large-scale public housing, to owner occupancy within what is legally a condominium (strata title or commonhold), to tenants renting from a private landlord (see leasehold estate).
Neoclassical synthesisThe neoclassical synthesis (NCS), neoclassical–Keynesian synthesis, or just neo-Keynesianism was a neoclassical economics academic movement and paradigm in economics that worked towards reconciling the macroeconomic thought of John Maynard Keynes in his book The General Theory of Employment, Interest and Money (1936). It was formulated most notably by John Hicks (1937), Franco Modigliani (1944), and Paul Samuelson (1948), who dominated economics in the post-war period and formed the mainstream of macroeconomic thought in the 1950s, 60s, and 70s.
ChiralityChirality kaɪˈrælɪtiː is a property of asymmetry important in several branches of science. The word chirality is derived from the Greek χειρ (kheir), "hand", a familiar chiral object. An object or a system is chiral if it is distinguishable from its ; that is, it cannot be superimposed onto it. Conversely, a mirror image of an achiral object, such as a sphere, cannot be distinguished from the object. A chiral object and its mirror image are called enantiomorphs (Greek, "opposite forms") or, when referring to molecules, enantiomers.
Solid-phase synthesisIn chemistry, solid-phase synthesis is a method in which molecules are covalently bound on a solid support material and synthesised step-by-step in a single reaction vessel utilising selective protecting group chemistry. Benefits compared with normal synthesis in a liquid state include: High efficiency and throughput Increased simplicity and speed The reaction can be driven to completion and high yields through the use of excess reagent. In this method, building blocks are protected at all reactive functional groups.
Chiral auxiliaryIn stereochemistry, a chiral auxiliary is a stereogenic group or unit that is temporarily incorporated into an organic compound in order to control the stereochemical outcome of the synthesis. The chirality present in the auxiliary can bias the stereoselectivity of one or more subsequent reactions. The auxiliary can then be typically recovered for future use. Most biological molecules and pharmaceutical targets exist as one of two possible enantiomers; consequently, chemical syntheses of natural products and pharmaceutical agents are frequently designed to obtain the target in enantiomerically pure form.
Butyl groupIn organic chemistry, butyl is a four-carbon alkyl radical or substituent group with general chemical formula , derived from either of the two isomers (n-butane and isobutane) of butane.
Enantioselective synthesisEnantioselective synthesis, also called asymmetric synthesis, is a form of chemical synthesis. It is defined by IUPAC as "a chemical reaction (or reaction sequence) in which one or more new elements of chirality are formed in a substrate molecule and which produces the stereoisomeric (enantiomeric or diastereomeric) products in unequal amounts." Put more simply: it is the synthesis of a compound by a method that favors the formation of a specific enantiomer or diastereomer.
New neoclassical synthesisThe new neoclassical synthesis (NNS), which is now generally referred to as New Keynesian economics, and occasionally as the New Consensus, is the fusion of the major, modern macroeconomic schools of thought – new classical macroeconomics/real business cycle theory and early New Keynesian economics – into a consensus view on the best way to explain short-run fluctuations in the economy. This new synthesis is analogous to the neoclassical synthesis that combined neoclassical economics with Keynesian macroeconomics.
Affordable housingAffordable housing is housing which is deemed affordable to those with a household income at or below the median as rated by the national government or a local government by a recognized housing affordability index. Most of the literature on affordable housing refers to mortgages and a number of forms that exist along a continuum – from emergency homeless shelters, to transitional housing, to non-market rental (also known as social or subsidized housing), to formal and informal rental, indigenous housing, and ending with affordable home ownership.
PyridinePyridine is a basic heterocyclic organic compound with the chemical formula . It is structurally related to benzene, with one methine group replaced by a nitrogen atom. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Pyridine is colorless, but older or impure samples can appear yellow, due to the formation of extended, unsaturated polymeric chains, which show significant electrical conductivity.
Concrete blockA concrete block, also known as a cinder block in North American English, breeze block in British English, concrete masonry unit (CMU), or by various other terms, is a standard-size rectangular block used in building construction. The use of blockwork allows structures to be built in the traditional masonry style with layers (or courses) of staggered blocks. Concrete blocks may be produced with hollow centers (cores) to reduce weight, improve insulation and provide an interconnected void into which concrete can be poured to solidify the entire wall after it is built.
