Publication

A Fully Fail-Safe Capacitive-Based Charge Metering Method for Active Charge Balancing in Deep Brain Stimulation

Alexandre Schmid, Reza Ranjandish
2018
Conference Papers

Abstract

Related to safety issues, charge balancing is a major concern in neural and functional electrical stimulation. This paper presents a capacitive-based charge metering method as a low-power and precise charge balancing method used in Deep Brain Stimulation (DBS). In contrast to the previously presented capacitive-based charge metering methods, the proposed method does not need any precise and high-speed comparator for net-zero charge detection. It is proven that this method is insensitive to the delay and the offset of its components. Consequently, using ultra-low power components in the charge balancer is feasible. Furthermore, the proposed method properly supports any stimulation mode and waveform. The proposed approach along with voltage and current mode pulse generators was validated in a 0.9% saline solution by using a DBS lead.

Official source

https://infoscience.epfl.ch/entities/publication/2ee9edc6-9677-49a6-b6fe-dcec9ab87975

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Alexandre Schmid, Reza Ranjandish
2018
Conference Papers

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/2ee9edc6-9677-49a6-b6fe-dcec9ab87975

About this result

Related concepts (15)

Neurostimulation

Neurostimulation is the purposeful modulation of the nervous system's activity using invasive (e.g. microelectrodes) or non-invasive means (e.g. transcranial magnetic stimulation or transcranial electric stimulation, tES, such as tDCS or transcranial alternating current stimulation, tACS). Neurostimulation usually refers to the electromagnetic approaches to neuromodulation.

Deep brain stimulation

Deep brain stimulation (DBS) is a neurosurgical procedure involving the placement of a medical device called a neurostimulator, which sends electrical impulses, through implanted electrodes, to specific targets in the brain (the brain nucleus) for the treatment of movement disorders, including Parkinson's disease, essential tremor, dystonia, and other conditions such as obsessive-compulsive disorder (OCD) and epilepsy. While its underlying principles and mechanisms are not fully understood, DBS directly changes brain activity in a controlled manner.

Euler method

In mathematics and computational science, the Euler method (also called the forward Euler method) is a first-order numerical procedure for solving ordinary differential equations (ODEs) with a given initial value. It is the most basic explicit method for numerical integration of ordinary differential equations and is the simplest Runge–Kutta method. The Euler method is named after Leonhard Euler, who first proposed it in his book Institutionum calculi integralis (published 1768–1870).

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