Protein structure predictionProtein structure prediction is the inference of the three-dimensional structure of a protein from its amino acid sequence—that is, the prediction of its secondary and tertiary structure from primary structure. Structure prediction is different from the inverse problem of protein design. Protein structure prediction is one of the most important goals pursued by computational biology; and it is important in medicine (for example, in drug design) and biotechnology (for example, in the design of novel enzymes).
Protein function predictionProtein function prediction methods are techniques that bioinformatics researchers use to assign biological or biochemical roles to proteins. These proteins are usually ones that are poorly studied or predicted based on genomic sequence data. These predictions are often driven by data-intensive computational procedures. Information may come from nucleic acid sequence homology, gene expression profiles, protein domain structures, text mining of publications, phylogenetic profiles, phenotypic profiles, and protein-protein interaction.
Multiphase flowIn fluid mechanics, multiphase flow is the simultaneous flow of materials with two or more thermodynamic phases. Virtually all processing technologies from cavitating pumps and turbines to paper-making and the construction of plastics involve some form of multiphase flow. It is also prevalent in many natural phenomena. These phases may consist of one chemical component (e.g. flow of water and water vapour), or several different chemical components (e.g. flow of oil and water).
Phase transitionIn chemistry, thermodynamics, and other related fields, a phase transition (or phase change) is the physical process of transition between one state of a medium and another. Commonly the term is used to refer to changes among the basic states of matter: solid, liquid, and gas, and in rare cases, plasma. A phase of a thermodynamic system and the states of matter have uniform physical properties. During a phase transition of a given medium, certain properties of the medium change as a result of the change of external conditions, such as temperature or pressure.
Gene predictionIn computational biology, gene prediction or gene finding refers to the process of identifying the regions of genomic DNA that encode genes. This includes protein-coding genes as well as RNA genes, but may also include prediction of other functional elements such as regulatory regions. Gene finding is one of the first and most important steps in understanding the genome of a species once it has been sequenced. In its earliest days, "gene finding" was based on painstaking experimentation on living cells and organisms.
Heat transferHeat transfer is a discipline of thermal engineering that concerns the generation, use, conversion, and exchange of thermal energy (heat) between physical systems. Heat transfer is classified into various mechanisms, such as thermal conduction, thermal convection, thermal radiation, and transfer of energy by phase changes. Engineers also consider the transfer of mass of differing chemical species (mass transfer in the form of advection), either cold or hot, to achieve heat transfer.
Numerical weather predictionNumerical weather prediction (NWP) uses mathematical models of the atmosphere and oceans to predict the weather based on current weather conditions. Though first attempted in the 1920s, it was not until the advent of computer simulation in the 1950s that numerical weather predictions produced realistic results. A number of global and regional forecast models are run in different countries worldwide, using current weather observations relayed from radiosondes, weather satellites and other observing systems as inputs.
PrecipitationIn meteorology, precipitation is any product of the condensation of atmospheric water vapor that falls from clouds due to gravitational pull. The main forms of precipitation include drizzle, rain, sleet, snow, ice pellets, graupel and hail. Precipitation occurs when a portion of the atmosphere becomes saturated with water vapor (reaching 100% relative humidity), so that the water condenses and "precipitates" or falls. Thus, fog and mist are not precipitation but colloids, because the water vapor does not condense sufficiently to precipitate.
Parametrization (climate modeling)Parameterization in a weather or climate model is a method of replacing processes that are too small-scale or complex to be physically represented in the model by a simplified process. This can be contrasted with other processes—e.g., large-scale flow of the atmosphere—that are explicitly resolved within the models. Associated with these parameterizations are various parameters used in the simplified processes.
PredictionA prediction (Latin præ-, "before," and dicere, "to say"), or forecast, is a statement about a future event or data. They are often, but not always, based upon experience or knowledge. There is no universal agreement about the exact difference from "estimation"; different authors and disciplines ascribe different connotations. Future events are necessarily uncertain, so guaranteed accurate information about the future is impossible. Prediction can be useful to assist in making plans about possible developments.
Global Environmental Multiscale ModelThe Global Environmental Multiscale Model (GEM), often known as the CMC model in North America, is an integrated forecasting and data assimilation system developed in the Recherche en Prévision Numérique (RPN), Meteorological Research Branch (MRB), and the Canadian Meteorological Centre (CMC). Along with the NWS's Global Forecast System (GFS), which runs out to 16 days, the ECMWF's Integrated Forecast System (IFS), which runs out 10 days, the Naval Research Laboratory Navy Global Environmental Model (NAVGEM), which runs out eight days, the UK Met Office's Unified Model, which runs out to seven days, and Deutscher Wetterdienst's ICON (ICOsahedral Nonhydrostatic), which runs out to 7.
Cloud physicsCloud physics is the study of the physical processes that lead to the formation, growth and precipitation of atmospheric clouds. These aerosols are found in the troposphere, stratosphere, and mesosphere, which collectively make up the greatest part of the homosphere. Clouds consist of microscopic droplets of liquid water (warm clouds), tiny crystals of ice (cold clouds), or both (mixed phase clouds), along with microscopic particles of dust, smoke, or other matter, known as condensation nuclei.
ConvectionConvection is single or multiphase fluid flow that occurs spontaneously due to the combined effects of material property heterogeneity and body forces on a fluid, most commonly density and gravity (see buoyancy). When the cause of the convection is unspecified, convection due to the effects of thermal expansion and buoyancy can be assumed. Convection may also take place in soft solids or mixtures where particles can flow. Convective flow may be transient (such as when a multiphase mixture of oil and water separates) or steady state (see Convection cell).
Atmospheric thermodynamicsAtmospheric thermodynamics is the study of heat-to-work transformations (and their reverse) that take place in the earth's atmosphere and manifest as weather or climate. Atmospheric thermodynamics use the laws of classical thermodynamics, to describe and explain such phenomena as the properties of moist air, the formation of clouds, atmospheric convection, boundary layer meteorology, and vertical instabilities in the atmosphere. Atmospheric thermodynamic diagrams are used as tools in the forecasting of storm development.
Lapse rateThe lapse rate is the rate at which an atmospheric variable, normally temperature in Earth's atmosphere, falls with altitude. Lapse rate arises from the word lapse, in the sense of a gradual fall. In dry air, the adiabatic lapse rate is 9.8 °C/km (5.4 °F per 1,000 ft). At Saturated Air Lapse Rate (SALR), where value is 1.1 °C/1000ft - 2.8 °C/1000ft as obtained from ICAO. It corresponds to the vertical component of the spatial gradient of temperature.
Liquid crystalLiquid crystal (LC) is a state of matter whose properties are between those of conventional liquids and those of solid crystals. For example, a liquid crystal may flow like a liquid, but its molecules may be oriented in a crystal-like way. There are many types of LC phases, which can be distinguished by their optical properties (such as textures). The contrasting textures arise due to molecules within one area of material ("domain") being oriented in the same direction but different areas having different orientations.
LiquidA liquid is a nearly incompressible fluid that conforms to the shape of its container but retains a nearly constant volume independent of pressure. It is one of the four fundamental states of matter (the others being solid, gas, and plasma), and is the only state with a definite volume but no fixed shape. The density of a liquid is usually close to that of a solid, and much higher than that of a gas. Therefore, liquid and solid are both termed condensed matter.
Tropical cyclone forecast modelA tropical cyclone forecast model is a computer program that uses meteorological data to forecast aspects of the future state of tropical cyclones. There are three types of models: statistical, dynamical, or combined statistical-dynamic. Dynamical models utilize powerful supercomputers with sophisticated mathematical modeling software and meteorological data to calculate future weather conditions. Statistical models forecast the evolution of a tropical cyclone in a simpler manner, by extrapolating from historical datasets, and thus can be run quickly on platforms such as personal computers.
TeleconnectionTeleconnection in atmospheric science refers to climate anomalies being related to each other at large distances (typically thousands of kilometers). The most emblematic teleconnection is that linking sea-level pressure at Tahiti and Darwin, Australia, which defines the Southern Oscillation. Another well-known teleconnection links the sea-level pressure over Iceland with the one over the Azores, traditionally defining the North Atlantic Oscillation (NAO).
Analytic philosophyAnalytic philosophy is a branch and tradition of philosophy using analysis, popular in the Western world and particularly the Anglosphere, which began around the turn of the 20th century in the contemporary era in the United Kingdom, United States, Canada, Australia, New Zealand, and Scandinavia, and continues today. Analytic philosophy is often contrasted with continental philosophy, coined as a catch-all term for other methods, prominent in Europe. Central figures in this historical development of analytic philosophy are Gottlob Frege, Bertrand Russell, G.
