Publication

Exciton dynamics in DNA oligomers studied by broadband deep-UV transient absorption spectroscopy

Majed Chergui, Malte Oppermann, Benjamin Bauer
2019
Conference Papers

Abstract

We report broadband transient absorption measurements of adenine strands in the deep-UV (250-370 nm). By varying the strand length we resolve the interplay between inter-base stacking and exciton formation and dynamics in DNA oligomers.

Official source

https://infoscience.epfl.ch/entities/publication/3f642f6e-35ed-437b-b906-1b0ee5b5dec2

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Majed Chergui, Malte Oppermann, Benjamin Bauer
2019
Conference Papers

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/3f642f6e-35ed-437b-b906-1b0ee5b5dec2

About this result

Related concepts (9)

Base pair

A base pair (bp) is a fundamental unit of double-stranded nucleic acids consisting of two nucleobases bound to each other by hydrogen bonds. They form the building blocks of the DNA double helix and contribute to the folded structure of both DNA and RNA. Dictated by specific hydrogen bonding patterns, "Watson–Crick" (or "Watson–Crick–Franklin") base pairs (guanine–cytosine and adenine–thymine) allow the DNA helix to maintain a regular helical structure that is subtly dependent on its nucleotide sequence.

DNA sequencing

DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, guanine, cytosine, and thymine. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery. Knowledge of DNA sequences has become indispensable for basic biological research, DNA Genographic Projects and in numerous applied fields such as medical diagnosis, biotechnology, forensic biology, virology and biological systematics.

Oligomer

In chemistry and biochemistry, an oligomer (əˈlɪgəmər) is a molecule that consists of a few repeating units which could be derived, actually or conceptually, from smaller molecules, monomers. The name is composed of Greek elements oligo-, "a few" and -mer, "parts". An adjective form is oligomeric. The oligomer concept is contrasted to that of a polymer, which is usually understood to have a large number of units, possibly thousands or millions. However, there is no sharp distinction between these two concepts.

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