Publications related to Apparatus and methods for treating excess intraocular fluid

A new self-adjustable glaucoma valve

Nikolaos Stergiopoulos, Stéphane Bigler, Julien Maxime Gerber, Soroush Rafiei

Introduction: Glaucoma, the leading cause of irreversible blindness globally, affects more than 70 million people across the world. When initial treatments prove ineffective, especially for cases with high intraocular pressure (IOP), the preferred approach ...

Frontiers Media Sa2024

Neuroprotection in the Retina: From Preventing Inflammatory Cell Death to Promoting Vascular Stability in the Central Nervous System

Bokyoung Kim

Glaucoma is one of the leading causes of irreversible blindness worldwide. Glaucoma is defined clinically as the presence of optic nerve head (ONH) degeneration and progressive loss of retinal ganglion cells (RGCs). Intra-ocular pressure (IOP) has been con ...

EPFL2024

Apparatus for treating excess intraocular fluid having an elastic membrane

Nikolaos Stergiopoulos, Constantinos Stergiopulos

Apparatus and methods are provided for treating diseases that produce elevated intraocular pressures, such as glaucoma, wherein the device includes a housing shell defining a cavity between a first end and a second end of the housing shell, and an elastic ...

2021

Intraocular Lens Refractive Index and Its Impact on External Surface Reflections

Georges Wagnières

PURPOSE: To determine and compare the origin of the external surface reflections produced by commonly used intraocular lenses (IOLs). ...

SLACK INC2021

Flexure-based mecano-optical multi-degree-of-freedom transducers dedicated to medical force sensing instruments

Sebastian Krzysztof Fifanski

This thesis develops novel multi-degrees-of-freedom flexure-based force sensors by exploiting white light interferometry. Fabry-Pérot interferometry measurement has nanometric accuracy which yields sub milli-Newton force sensing accuracy. Such force sensin ...

EPFL2020

Apparatus for treating excess intraocular fluid having an elastic membrane

Nikolaos Stergiopoulos, Constantinos Stergiopulos

A device (100) is provided for treating diseases that produce elevated intraocular pressures, such as glaucoma, wherein the device (100) includes a housing shell (101) defining a cavity (107) between a first end (102) and a second end (104) of the housing ...

2020

EyeWatch Rescue of Refractory Hypotony After Baerveldt Drainage Device Implantation: Description of a New Technique

André Mermoud, Nikolaos Stergiopoulos, Adan Villamarin, Sina Elahi

The most effective way to control glaucoma is by lowering intraocular pressure (IOP) in order to prevent the progression of the disease. Glaucoma drainage devices (GDDs) are surgical option reserved for refractory cases and have been designed to address kn ...

LIPPINCOTT WILLIAMS & WILKINS2020

MRI after successful eyeWatch(TM) implantation

André Mermoud, Nikolaos Stergiopoulos, Sylvain Roy, Adan Villamarin

The eyeWatch(TM) is a new glaucoma drainage device that includes an adjustable mechanism that can vary the resistance to aqueous humor outflow during the postoperative period to reduce the burden of postoperative intraocular pressure (IOP) management. The ...

SAGE PUBLICATIONS LTD2020

Outcome and Complications of Combined Modified Deep Sclerectomy and Trabeculectomy for Surgical Management of Glaucoma: A Pilot Study

André Mermoud, Sylvain Roy

Purpose: To report the outcome and complications of a combined surgical technique of modified deep sclerectomy and trabeculectomy (mDST) for glaucoma. Patients and Methods: Retrospective study of 44 eyes of 43 patients with open and closed angle glaucoma w ...

2020

Comparison Between the eyeWatch Device and the Ahmed Valve in Refractory Glaucoma

André Mermoud, Nikolaos Stergiopoulos, Sylvain Roy, Adan Villamarin, Stéphane Bigler, Constantinos Stergiopulos

Purpose: To assess the efficacy and safety of a glaucoma procedure to control intraocular pressure (IOP) using the adjustable eyeWatch glaucoma drainage device compared with Ahmed glaucoma valve (AGV) in refractory glaucoma. Patients and Methods: Monocentr ...

LIPPINCOTT WILLIAMS & WILKINS2020

Initial Clinical Results of the eyeWatch: a New Adjustable Glaucoma Drainage Device Used in Refractory Glaucoma Surgery

André Mermoud, Nikolaos Stergiopoulos, Sylvain Roy, Adan Villamarin, Stéphane Bigler, Constantinos Stergiopulos

Precis: In this study, we report clinical results after implantation of an adjustable glaucoma drainage device. The intraocular pressure (IOP) profile was efficiently controlled postoperatively as the resistance to aqueous humor outflow was finely adjusted ...

LIPPINCOTT WILLIAMS & WILKINS2019

Design and validation of a foldable and photovoltaic wide-field epiretinal prosthesis

Kevin Sivula, Naïg Aurelia Ludmilla Chenais, Samuel Charles Antoine Gilliéron, Marta Jole Ildelfonsa Airaghi Leccardi, Diego Ghezzi, Michele Bevilacqua, Paola Vagni, Laura Ferlauto

Retinal prostheses have been developed to fight blindness in people affected by outer retinal layer dystrophies. To date, few hundred patients have received a retinal implant. Inspired by intraocular lenses, we have designed a foldable and photovoltaic wid ...

Nature Research2018

A field-based modelling framework of the ecohydrology of schistosomiasis

Francisco Javier Perez Saez

Successful control of schistosomiasis, a water-borne parasitic disease, is challenged by the intricacy of the wormâ s lifecycle, which depends on aquatic snail intermediate hosts, and involves environmental, ecologic, and socio-economic factors. Current s ...

EPFL2018

Apparatus for treating excess intraocular fluid

Nikolaos Stergiopoulos, Constantinos Stergiopulos

Apparatus and methods are provided for treating diseases that produce elevated intraocular pressures, such as glaucoma, wherein the device operates on the principles of a Starling resistor, and includes a housing, a deformable structure and a spring mounte ...

2017

Results of CO2 Laser-assisted Deep Sclerectomy as Compared With Conventional Deep Sclerectomy

André Mermoud, Sylvain Roy

Purpose: To evaluate the efficacy of CO2 laser-assisted sclerectomy surgery (CLASS) compared with classic nonpenetrating deep sclerectomy (NPDS) with implant in medically uncontrolled glaucoma patients. Materials and Methods: Patients who underwent primary ...

Lippincott, Williams & Wilkins2016

Eyewatch, an Innovative Adjustable GDD for the Treatment of Glaucoma - in Vivo Results

André Mermoud, Nikolaos Stergiopoulos, Sylvain Roy, Adan Villamarin, Stéphane Bigler

PURPOSE: To report the in vivo results of a continuously adjustable glaucoma drainage device (GDD) in glaucoma surgery with rabbits. METHODS: Under general anesthesia, the AGDD was implanted on 12 white New-Zealand rabbits for duration of 6 months. The adj ...

Springer2016

JNK Inhibition Reduced Retinal Ganglion Cell Death after Ischemia/Reperfusion In Vivo and after Hypoxia In Vitro

Tatiana Favez

Mitogen-activated protein kinases (MAPKs) are key regulators that have been linked to cell survival and death. Among the main classes of MAPKs, c-jun N-terminal kinase (JNK) has been shown to mediate cell stress responses associated with apoptosis. In Vitr ...

Springer Int Publishing Ag2016

Institutions, Innovation and Public Health

Viviana Carolina Munoz Tellez de Kieffer

This study concerns the economics of innovation in the area of medical innovation -new diagnostics, medicines and vaccines-, and in particular how innovation contributes to meeting public health needs. Significant advances have taken place in medical scien ...

EPFL2015

A New Noninvasively Adjustable Glaucoma Drainage Device

Adan Villamarin

Glaucoma is an irreversible disease affecting the eye, leading to progressive loss of vision and eventually to total blindness. It is often related to high intraocular pressure (IOP), which results from increased outflow resistance to aqueous humor. The fi ...

EPFL2014

In Vivo Testing of a Novel Adjustable Glaucoma Drainage Device

André Mermoud, Nikolaos Stergiopoulos, Sylvain Roy, Adan Villamarin, Stéphane Bigler

PURPOSE. We report on the in vivo testing of a novel noninvasively adjustable glaucoma drainage device (AGDD), which features an adjustable outflow resistance, and assess the safety and efficiency of this implant. METHODS. Under general anesthesia, the AGD ...

Association for Research in Vision and Ophthalmology2014