Organic synthesisOrganic synthesis is a special branch of chemical synthesis and is concerned with the intentional construction of organic compounds. Organic molecules are often more complex than inorganic compounds, and their synthesis has developed into one of the most important branches of organic chemistry. There are several main areas of research within the general area of organic synthesis: total synthesis, semisynthesis, and methodology.
Quantifier eliminationQuantifier elimination is a concept of simplification used in mathematical logic, model theory, and theoretical computer science. Informally, a quantified statement " such that " can be viewed as a question "When is there an such that ?", and the statement without quantifiers can be viewed as the answer to that question. One way of classifying formulas is by the amount of quantification. Formulas with less depth of quantifier alternation are thought of as being simpler, with the quantifier-free formulas as the simplest.
General-purpose programming languageIn computer software, a general-purpose programming language (GPL) is a programming language for building software in a wide variety of application domains. Conversely, a domain-specific programming language (DSL) is used within a specific area. For example, Python is a GPL, while SQL is a DSL for querying relational databases. Early programming languages were designed for scientific computing (numerical calculations) or commercial data processing, as was computer hardware.
Scala (programming language)Scala (ˈskɑːlə ) is a strong statically typed high-level general-purpose programming language that supports both object-oriented programming and functional programming. Designed to be concise, many of Scala's design decisions are aimed to address criticisms of Java. Scala source code can be compiled to Java bytecode and run on a Java virtual machine (JVM). Scala can also be compiled to JavaScript to run in a browser, or directly to a native executable.
Solid-phase synthesisIn chemistry, solid-phase synthesis is a method in which molecules are covalently bound on a solid support material and synthesised step-by-step in a single reaction vessel utilising selective protecting group chemistry. Benefits compared with normal synthesis in a liquid state include: High efficiency and throughput Increased simplicity and speed The reaction can be driven to completion and high yields through the use of excess reagent. In this method, building blocks are protected at all reactive functional groups.
High-level synthesisHigh-level synthesis (HLS), sometimes referred to as C synthesis, electronic system-level (ESL) synthesis, algorithmic synthesis, or behavioral synthesis, is an automated design process that takes an abstract behavioral specification of a digital system and finds a register-transfer level structure that realizes the given behavior. Synthesis begins with a high-level specification of the problem, where behavior is generally decoupled from low-level circuit mechanics such as clock-level timing.
Quantifier (logic)In logic, a quantifier is an operator that specifies how many individuals in the domain of discourse satisfy an open formula. For instance, the universal quantifier in the first order formula expresses that everything in the domain satisfies the property denoted by . On the other hand, the existential quantifier in the formula expresses that there exists something in the domain which satisfies that property. A formula where a quantifier takes widest scope is called a quantified formula.
F Sharp (programming language)F# (pronounced F sharp) is a functional-first, general-purpose, strongly typed, multi-paradigm programming language that encompasses functional, imperative, and object-oriented programming methods. It is most often used as a cross-platform Common Language Infrastructure (CLI) language on .NET, but can also generate JavaScript and graphics processing unit (GPU) code. F# is developed by the F# Software Foundation, Microsoft and open contributors. An open source, cross-platform compiler for F# is available from the F# Software Foundation.
Danishefsky Taxol total synthesisThe Danishefsky Taxol total synthesis in organic chemistry is an important third Taxol synthesis published by the group of Samuel Danishefsky in 1996 two years after the first two efforts described in the Holton Taxol total synthesis and the Nicolaou Taxol total synthesis. Combined they provide a good insight in the application of organic chemistry in total synthesis. Danishefsky's route to Taxol has many similarities with that of Nicolaou. Both are examples of convergent synthesis with a coupling of the A and the C ring from two precursors.
Kotlin (programming language)Kotlin (ˈkɒtlɪn) is a cross-platform, statically typed, general-purpose high-level programming language with type inference. Kotlin is designed to interoperate fully with Java, and the JVM version of Kotlin's standard library depends on the Java Class Library, but type inference allows its syntax to be more concise. Kotlin mainly targets the JVM, but also compiles to JavaScript (e.g., for frontend web applications using React) or native code via LLVM (e.g., for native iOS apps sharing business logic with Android apps).
Existential quantificationIn predicate logic, an existential quantification is a type of quantifier, a logical constant which is interpreted as "there exists", "there is at least one", or "for some". It is usually denoted by the logical operator symbol ∃, which, when used together with a predicate variable, is called an existential quantifier ("∃x" or "∃(x)" or "(∃x)"). Existential quantification is distinct from universal quantification ("for all"), which asserts that the property or relation holds for all members of the domain.
Program transformationA program transformation is any operation that takes a computer program and generates another program. In many cases the transformed program is required to be semantically equivalent to the original, relative to a particular formal semantics and in fewer cases the transformations result in programs that semantically differ from the original in predictable ways. While the transformations can be performed manually, it is often more practical to use a program transformation system that applies specifications of the required transformations.
Comparison of programming languagesProgramming languages are used for controlling the behavior of a machine (often a computer). Like natural languages, programming languages follow rules for syntax and semantics. There are thousands of programming languages and new ones are created every year. Few languages ever become sufficiently popular that they are used by more than a few people, but professional programmers may use dozens of languages in a career. Most programming languages are not standardized by an international (or national) standard, even widely used ones, such as Perl or Standard ML (despite the name).
Binary relationIn mathematics, a binary relation associates elements of one set, called the domain, with elements of another set, called the codomain. A binary relation over sets X and Y is a new set of ordered pairs (x, y) consisting of elements x in X and y in Y. It is a generalization of the more widely understood idea of a unary function. It encodes the common concept of relation: an element x is related to an element y, if and only if the pair (x, y) belongs to the set of ordered pairs that defines the binary relation.
Domain theoryDomain theory is a branch of mathematics that studies special kinds of partially ordered sets (posets) commonly called domains. Consequently, domain theory can be considered as a branch of order theory. The field has major applications in computer science, where it is used to specify denotational semantics, especially for functional programming languages. Domain theory formalizes the intuitive ideas of approximation and convergence in a very general way and is closely related to topology.
ML (programming language)ML (Meta Language) is a general-purpose functional programming language. It is known for its use of the polymorphic Hindley–Milner type system, which automatically assigns the types of most expressions without requiring explicit type annotations, and ensures type safety - there is a formal proof that a well-typed ML program does not cause runtime type errors. ML provides pattern matching for function arguments, garbage collection, imperative programming, call-by-value and currying.
Speech synthesisSpeech synthesis is the artificial production of human speech. A computer system used for this purpose is called a speech synthesizer, and can be implemented in software or hardware products. A text-to-speech (TTS) system converts normal language text into speech; other systems render symbolic linguistic representations like phonetic transcriptions into speech. The reverse process is speech recognition. Synthesized speech can be created by concatenating pieces of recorded speech that are stored in a database.
Global variableIn computer programming, a global variable is a variable with global scope, meaning that it is visible (hence accessible) throughout the program, unless shadowed. The set of all global variables is known as the global environment or global state. In compiled languages, global variables are generally static variables, whose extent (lifetime) is the entire runtime of the program, though in interpreted languages (including command-line interpreters), global variables are generally dynamically allocated when declared, since they are not known ahead of time.
NegationIn logic, negation, also called the logical not or logical complement, is an operation that takes a proposition to another proposition "not ", standing for " is not true", written , or . It is interpreted intuitively as being true when is false, and false when is true. Negation is thus a unary logical connective. It may be applied as an operation on notions, propositions, truth values, or semantic values more generally. In classical logic, negation is normally identified with the truth function that takes truth to falsity (and vice versa).
Universal instantiationIn predicate logic, universal instantiation (UI; also called universal specification or universal elimination, and sometimes confused with dictum de omni) is a valid rule of inference from a truth about each member of a class of individuals to the truth about a particular individual of that class. It is generally given as a quantification rule for the universal quantifier but it can also be encoded in an axiom schema. It is one of the basic principles used in quantification theory. Example: "All dogs are mammals.
