LeprosyLeprosy, also known as Hansen's disease (HD), is a long-term infection by the bacteria Mycobacterium leprae or Mycobacterium lepromatosis. Infection can lead to damage of the nerves, respiratory tract, skin, and eyes. This nerve damage may result in a lack of ability to feel pain, which can lead to the loss of parts of a person's extremities from repeated injuries or infection through unnoticed wounds. An infected person may also experience muscle weakness and poor eyesight.
Mycobacterium lepraeMycobacterium leprae (also known as the leprosy bacillus or Hansen's bacillus) is one of the two species of bacteria that cause Hansen’s disease (leprosy), a chronic but curable infectious disease that damages the peripheral nerves and targets the skin, eyes, nose, and muscles. It is an acid-fast, Gram-positive, rod shaped bacterium and an obligate intracellular parasite, which means, unlike its relative Mycobacterium tuberculosis, it cannot be grown in cell-free laboratory media.
United StatesThe United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America and consisting of 50 states, a federal district, five major unincorporated territories, nine Minor Outlying Islands, and 326 Indian reservations. It is the world's third-largest country by both land and total area. It shares land borders with Canada to its north and with Mexico to its south and has maritime borders with the Bahamas, Cuba, Russia, and other nations.
LouisianaLouisiana (La Louisiane la lwizjan; La Luisiana) is a state in the Deep South and South Central regions of the United States. It is bordered by the state of Texas to the west, Arkansas to the north, Mississippi to the east, and the Gulf of Mexico to the south; a large part of its eastern boundary is demarcated by the Mississippi River. Of the 50 U.S. states, it ranks 20th in land area and the 25th in population, with roughly 4.6 million residents. Reflecting its French heritage, Louisiana is the only U.S.
TexasTexas (ˈtɛksəs, ˈtɛksᵻz; Spanish: Texas, Tejas) is a state in the South Central region of the United States. At , and with more than 30 million residents in 2023, it is the second-largest U.S. state by both area (after Alaska) and population (after California). Texas shares borders with the states of Louisiana to the east, Arkansas to the northeast, Oklahoma to the north, New Mexico to the west, and the Mexican states of Chihuahua, Coahuila, Nuevo León, and Tamaulipas to the south and southwest; and has a coastline with the Gulf of Mexico to the southeast.
Citizenship of the United StatesCitizenship of the United States is a legal status that entails Americans with specific rights, duties, protections, and benefits in the United States. It serves as a foundation of fundamental rights derived from and protected by the Constitution and laws of the United States, such as freedom of expression, due process, the rights to vote (however, not all citizens have the right to vote in all federal elections, for example, those living in Puerto Rico), live and work in the United States, and to receive federal assistance.
MycobacteriumMycobacterium is a genus of over 190 species in the phylum Actinomycetota, assigned its own family, Mycobacteriaceae. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis (M. tuberculosis) and leprosy (M. leprae) in humans. The Greek prefix myco- means 'fungus', alluding to this genus' mold-like colony surfaces. Since this genus has cell walls with a waxy lipid-rich outer layer that contains high concentrations of mycolic acid, acid-fast staining is used to emphasize their resistance to acids, compared to other cell types.
Louisiana PurchaseThe Louisiana Purchase (Vente de la Louisiane) was the acquisition of the territory of Louisiana by the United States from the French First Republic in 1803. This consisted of most of the land in the Mississippi River's drainage basin west of the river. In return for fifteen million dollars, or approximately eighteen dollars per square mile, the United States nominally acquired a total of in Middle America.
Native Americans in the United StatesNative Americans, sometimes called First Americans or Indigenous Americans, are the Indigenous peoples of the United States or portions thereof, such as American Indians from the contiguous United States and Alaska Natives. The United States Census Bureau defines Native American as "all people indigenous to the United States and its territories—including Native Hawaiian and Other Pacific Islanders—whose data are published separately from American Indians and Alaska Natives".
MexicoMexico (Spanish: México), officially the United Mexican States, is a country in the southern portion of North America. It is bordered to the north by the United States; to the south and west by the Pacific Ocean; to the southeast by Guatemala, Belize, and the Caribbean Sea; and to the east by the Gulf of Mexico. Mexico covers 1,972,550 km2 (761,610 sq mi), making it the world's 13th-largest country by area; with a population of over 126 million, it is the 10th-most-populous country and has the most Spanish speakers.
Foreign relations of the United StatesThe United States has formal diplomatic relations with most nations. This includes all United Nations members and observer states other than Bhutan, Iran, North Korea and Syria, and the UN observer State of Palestine, the last of which the U.S. does not recognize. Additionally, the U.S. has diplomatic relations with Kosovo and the European Union. The United States federal statutes relating to foreign relations can be found in Title 22 of the United States Code. The United States has the most diplomatic posts of any state.
New MexicoNew Mexico (Nuevo México ˈnweβo ˈmexiko; Yootó Hahoodzo jòːthó hɑ̀hòːtsò) is a state in the Southwestern United States. It is one of the Mountain States of the southern Rocky Mountains, sharing the Four Corners region of the western U.S. with Utah, Colorado, and Arizona, and bordering Texas to the east and southeast, Oklahoma to the northeast, and the Mexican states of Chihuahua and Sonora to the south. New Mexico's largest city is Albuquerque, and its state capital is Santa Fe, the oldest state capital in the U.
HistoryHistory (derived ) is the systematic study and documentation of the human past. The period of events before the invention of writing systems is considered prehistory. "History" is an umbrella term comprising past events as well as the memory, discovery, collection, organization, presentation, and interpretation of these events. Historians seek knowledge of the past using historical sources such as written documents, oral accounts, art and material artifacts, and ecological markers.
Mexico CityMexico City (Ciudad de México, sjuˈða(ð) ðe ˈmexiko; abbr.: CDMX; Nahuatl: Āltepētl Mēxihco ɑːl'tɛpeːt͡ɬ meːʃi'ko) is the capital and largest city of Mexico, and the most populous city in North America. One of the world's alpha cities, it is located in the Valley of Mexico within the high Mexican central plateau, at an altitude of . The city has 16 boroughs or demarcaciones territoriales, which are in turn divided into neighborhoods or colonias. The 2020 population for the city proper was 9,209,944, with a land area of .
Republic of TexasThe Republic of Texas (República de Tejas) was a sovereign state in North America that existed from March 2, 1836, to February 19, 1846, that bordered Mexico, the Republic of the Rio Grande in 1840 (another breakaway republic from Mexico), and the United States of America, although Mexico considered it a rebellious province during its entire existence despite the Treaties of Velasco of May 1836. It was bordered by Mexico to the west and southwest, the Gulf of Mexico to the southeast, the two U.S.
State of MexicoThe State of Mexico (Estado de México; esˈtaðo ðe ˈmexiko), officially just Mexico (México), is one of the 32 federal entities of the United Mexican States. Commonly known as Edomex (from Estado de México) to distinguish it from the name of the whole country, it is the most populous, as well as the most densely populated, state in the country. Located in south-central Mexico, the state is divided into 125 municipalities. The state capital city is Toluca de Lerdo ("Toluca"), while its largest city is Ecatepec de Morelos ("Ecatepec").
Southern United StatesThe Southern United States (sometimes Dixie, also referred to as the Southern States, the American South, the Southland, Dixieland, or simply the South) is a geographic and cultural region of the United States of America. It is between the Atlantic Ocean and the Western United States, with the Midwestern and Northeastern United States to its north and the Gulf of Mexico and Mexico to its south. Historically, the South was defined as all states south of the 18th century Mason–Dixon line, the Ohio River, and 36°30′ parallel.
Intellectual historyIntellectual history (also the history of ideas) is the study of the history of human thought and of intellectuals, people who conceptualize, discuss, write about, and concern themselves with ideas. The investigative premise of intellectual history is that ideas do not develop in isolation from the thinkers who conceptualize and apply those ideas; thus the intellectual historian studies ideas in two contexts: (i) as abstract propositions for critical application; and (ii) in concrete terms of culture, life, and history.
Culture of the Southern United StatesThe culture of the Southern United States, Southern culture, or Southern heritage, is a subculture of the United States. From its many cultural influences, the South developed its own unique customs, dialects, arts, literature, cuisine, dance, and music. The combination of its unique history and the fact that many Southerners maintain—and even nurture—an identity separate from the rest of the country has led to it being the most studied and written-about region of the U.S.
Counterfactual historyCounterfactual history (also virtual history) is a form of historiography that attempts to answer the What if? questions that arise from counterfactual conditions. As a method of intellectual enquiry, counterfactual history explores history and historical incidents by extrapolating a timeline in which key historical events either did not occur or had an outcome different from the actual historical outcome. Counterfactual history seeks by "conjecturing on what did not happen, or what might have happened, in order to understand what did happen.