Biological neuron modelBiological neuron models, also known as a spiking neuron models, are mathematical descriptions of the properties of certain cells in the nervous system that generate sharp electrical potentials across their cell membrane, roughly one millisecond in duration, called action potentials or spikes (Fig. 2). Since spikes are transmitted along the axon and synapses from the sending neuron to many other neurons, spiking neurons are considered to be a major information processing unit of the nervous system.
Parallel computingParallel computing is a type of computation in which many calculations or processes are carried out simultaneously. Large problems can often be divided into smaller ones, which can then be solved at the same time. There are several different forms of parallel computing: bit-level, instruction-level, data, and task parallelism. Parallelism has long been employed in high-performance computing, but has gained broader interest due to the physical constraints preventing frequency scaling.
SimulationA simulation is the imitation of the operation of a real-world process or system over time. Simulations require the use of models; the model represents the key characteristics or behaviors of the selected system or process, whereas the simulation represents the evolution of the model over time. Often, computers are used to execute the simulation. Simulation is used in many contexts, such as simulation of technology for performance tuning or optimizing, safety engineering, testing, training, education, and video games.
Single instruction, multiple dataSingle instruction, multiple data (SIMD) is a type of parallel processing in Flynn's taxonomy. SIMD can be internal (part of the hardware design) and it can be directly accessible through an instruction set architecture (ISA), but it should not be confused with an ISA. SIMD describes computers with multiple processing elements that perform the same operation on multiple data points simultaneously. Such machines exploit data level parallelism, but not concurrency: there are simultaneous (parallel) computations, but each unit performs the exact same instruction at any given moment (just with different data).
Computational neuroscienceComputational neuroscience (also known as theoretical neuroscience or mathematical neuroscience) is a branch of neuroscience which employs mathematical models, computer simulations, theoretical analysis and abstractions of the brain to understand the principles that govern the development, structure, physiology and cognitive abilities of the nervous system. Computational neuroscience employs computational simulations to validate and solve mathematical models, and so can be seen as a sub-field of theoretical neuroscience; however, the two fields are often synonymous.
Hardware accelerationHardware acceleration is the use of computer hardware designed to perform specific functions more efficiently when compared to software running on a general-purpose central processing unit (CPU). Any transformation of data that can be calculated in software running on a generic CPU can also be calculated in custom-made hardware, or in some mix of both. To perform computing tasks more quickly (or better in some other way), generally one can invest time and money in improving the software, improving the hardware, or both.
Granularity (parallel computing)In parallel computing, granularity (or grain size) of a task is a measure of the amount of work (or computation) which is performed by that task. Another definition of granularity takes into account the communication overhead between multiple processors or processing elements. It defines granularity as the ratio of computation time to communication time, wherein computation time is the time required to perform the computation of a task and communication time is the time required to exchange data between processors.
ComputingComputing is any goal-oriented activity requiring, benefiting from, or creating computing machinery. It includes the study and experimentation of algorithmic processes, and development of both hardware and software. Computing has scientific, engineering, mathematical, technological and social aspects. Major computing disciplines include computer engineering, computer science, cybersecurity, data science, information systems, information technology, digital art and software engineering.
Distributed computingA distributed system is a system whose components are located on different networked computers, which communicate and coordinate their actions by passing messages to one another. Distributed computing is a field of computer science that studies distributed systems. The components of a distributed system interact with one another in order to achieve a common goal. Three significant challenges of distributed systems are: maintaining concurrency of components, overcoming the lack of a global clock, and managing the independent failure of components.
Grid computingGrid computing is the use of widely distributed computer resources to reach a common goal. A computing grid can be thought of as a distributed system with non-interactive workloads that involve many files. Grid computing is distinguished from conventional high-performance computing systems such as cluster computing in that grid computers have each node set to perform a different task/application. Grid computers also tend to be more heterogeneous and geographically dispersed (thus not physically coupled) than cluster computers.
Cloud computingCloud computing is the on-demand availability of computer system resources, especially data storage (cloud storage) and computing power, without direct active management by the user. Large clouds often have functions distributed over multiple locations, each of which is a data center. Cloud computing relies on sharing of resources to achieve coherence and typically uses a pay-as-you-go model, which can help in reducing capital expenses but may also lead to unexpected operating expenses for users.
Blue Brain ProjectThe Blue Brain Project is a Swiss brain research initiative that aims to create a digital reconstruction of the mouse brain. The project was founded in May 2005 by the Brain and Mind Institute of École Polytechnique Fédérale de Lausanne (EPFL) in Switzerland. Its mission is to use biologically-detailed digital reconstructions and simulations of the mammalian brain to identify the fundamental principles of brain structure and function.
Instruction-level parallelismInstruction-level parallelism (ILP) is the parallel or simultaneous execution of a sequence of instructions in a computer program. More specifically ILP refers to the average number of instructions run per step of this parallel execution. ILP must not be confused with concurrency. In ILP there is a single specific thread of execution of a process. On the other hand, concurrency involves the assignment of multiple threads to a CPU's core in a strict alternation, or in true parallelism if there are enough CPU cores, ideally one core for each runnable thread.
Distributed operating systemA distributed operating system is system software over a collection of independent software, networked, communicating, and physically separate computational nodes. They handle jobs which are serviced by multiple CPUs. Each individual node holds a specific software subset of the global aggregate operating system. Each subset is a composite of two distinct service provisioners. The first is a ubiquitous minimal kernel, or microkernel, that directly controls that node's hardware.
NeuroinformaticsNeuroinformatics is the field that combines informatics and neuroscience. Neuroinformatics is related with neuroscience data and information processing by artificial neural networks. There are three main directions where neuroinformatics has to be applied: the development of computational models of the nervous system and neural processes.
NeuronWithin a nervous system, a neuron, neurone, or nerve cell is an electrically excitable cell that fires electric signals called action potentials across a neural network. Neurons communicate with other cells via synapses - specialized connections that commonly use minute amounts of chemical neurotransmitters to pass the electric signal from the presynaptic neuron to the target cell through the synaptic gap. The neuron is the main component of nervous tissue in all animals except sponges and placozoa.
Single instruction, multiple threadsSingle instruction, multiple threads (SIMT) is an execution model used in parallel computing where single instruction, multiple data (SIMD) is combined with multithreading. It is different from SPMD in that all instructions in all "threads" are executed in lock-step. The SIMT execution model has been implemented on several GPUs and is relevant for general-purpose computing on graphics processing units (GPGPU), e.g. some supercomputers combine CPUs with GPUs. The processors, say a number p of them, seem to execute many more than p tasks.
Massively parallel processor arrayA massively parallel processor array, also known as a multi purpose processor array (MPPA) is a type of integrated circuit which has a massively parallel array of hundreds or thousands of CPUs and RAM memories. These processors pass work to one another through a reconfigurable interconnect of channels. By harnessing a large number of processors working in parallel, an MPPA chip can accomplish more demanding tasks than conventional chips. MPPAs are based on a software parallel programming model for developing high-performance embedded system applications.
Distributed memoryIn computer science, distributed memory refers to a multiprocessor computer system in which each processor has its own private memory. Computational tasks can only operate on local data, and if remote data are required, the computational task must communicate with one or more remote processors. In contrast, a shared memory multiprocessor offers a single memory space used by all processors. Processors do not have to be aware where data resides, except that there may be performance penalties, and that race conditions are to be avoided.
Graphics processing unitA graphics processing unit (GPU) is a specialized electronic circuit initially designed to accelerate computer graphics and (either on a video card or embedded on the motherboards, mobile phones, personal computers, workstations, and game consoles). After their initial design, GPUs were found to be useful for non-graphic calculations involving embarrassingly parallel problems due to their parallel structure. Other non-graphical uses include the training of neural networks and cryptocurrency mining.
