Publication

Method for hyperpolarization transfer in the liquid state

Geoffrey Bodenhausen, Sami Jannin
2014
Patents

Abstract

A method for producing a hyperpolarized sample for use in a magnetic resonance investigation, with the following steps: a) providing a solid sample (50), containing long T1 nuclei and short T1 nuclei in the same molecules (51) b) hyperpolarizing the short T1 nuclei in the solid sample (50), c) transforming the solid sample (50) into a liquid sample (52), d) transferring the polarization of the short T1 nuclei to the long T1 nuclei within the molecules in the liquid sample (52) by Cross Polarization. The invention provides a method which can provide samples with hyperpolarized long T1 nuclei, in particular 13C or 15N, in a simple and efficient way.

Official source

https://infoscience.epfl.ch/entities/publication/7efe5b17-9b3b-4592-9ad7-3b33aa98d952

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Geoffrey Bodenhausen, Sami Jannin
2014
Patents

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/7efe5b17-9b3b-4592-9ad7-3b33aa98d952

About this result

Related concepts (13)

Nuclear magnetic resonance

Nuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a strong constant magnetic field are perturbed by a weak oscillating magnetic field (in the near field) and respond by producing an electromagnetic signal with a frequency characteristic of the magnetic field at the nucleus. This process occurs near resonance, when the oscillation frequency matches the intrinsic frequency of the nuclei, which depends on the strength of the static magnetic field, the chemical environment, and the magnetic properties of the isotope involved; in practical applications with static magnetic fields up to ca.

Magnetic resonance imaging

Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves to generate images of the organs in the body. MRI does not involve X-rays or the use of ionizing radiation, which distinguishes it from computed tomography (CT) and positron emission tomography (PET) scans.

Polarization (physics)

Polarization (also polarisation) is a property of transverse waves which specifies the geometrical orientation of the oscillations. In a transverse wave, the direction of the oscillation is perpendicular to the direction of motion of the wave. A simple example of a polarized transverse wave is vibrations traveling along a taut string (see image); for example, in a musical instrument like a guitar string. Depending on how the string is plucked, the vibrations can be in a vertical direction, horizontal direction, or at any angle perpendicular to the string.

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