Publication

Novel biosensor for detecting Hemoglobin and its oxidation state based on nonreciprocity in a coupled waveguide system

Olivier Martin, Shourya Dutta Gupta
2012
Conference Papers

Abstract

We study the reflection of a tightly focused Gaussian beam off a near symmetric resonant tunneling structure comprising two identical coupled waveguides. The coupled waveguides are loaded on each side by a spacer layer and a high index prism. Reflection of a Gaussian beam from such a resonant structure is associated with beam distortion and even beam splitting. We start with the distortion of the beam profile for a symmetric structure as a function of various parameters of the system. The broken spatial symmetry is introduced through the reference channel on one side and the sample channel on the other side as spacer layers. We monitor the dip in the beam profile when the two channels are filled with the sample and the reference liquid. We show that presence and absence of hemoglobin and its oxygenation states can be quantified by looking at the beam profile dip. Our results may find applications in high resolution sensing.

Official source

https://infoscience.epfl.ch/entities/publication/851fd1bf-774c-4cca-8da2-930fe35c5ae1

About this result

This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.

Olivier Martin, Shourya Dutta Gupta
2012
Conference Papers

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/851fd1bf-774c-4cca-8da2-930fe35c5ae1

About this result

Related concepts (27)

Waveguide filter

A waveguide filter is an electronic filter constructed with waveguide technology. Waveguides are hollow metal conduits inside which an electromagnetic wave may be transmitted. Filters are devices used to allow signals at some frequencies to pass (the passband), while others are rejected (the stopband). Filters are a basic component of electronic engineering designs and have numerous applications. These include selection of signals and limitation of noise.

Physical layer

In the seven-layer OSI model of computer networking, the physical layer or layer 1 is the first and lowest layer: the layer most closely associated with the physical connection between devices. The physical layer provides an electrical, mechanical, and procedural interface to the transmission medium. The shapes and properties of the electrical connectors, the frequencies to broadcast on, the line code to use and similar low-level parameters, are specified by the physical layer.

Gaussian beam

In optics, a Gaussian beam is a beam of electromagnetic radiation with high monochromaticity whose amplitude envelope in the transverse plane is given by a Gaussian function; this also implies a Gaussian intensity (irradiance) profile. This fundamental (or TEM00) transverse Gaussian mode describes the intended output of most (but not all) lasers, as such a beam can be focused into the most concentrated spot. When such a beam is refocused by a lens, the transverse phase dependence is altered; this results in a different Gaussian beam.

Related publications (30)

All-Dielectric Nanophotonic via Glass Fluid Instabilities

Pierre-Luc Eloi Piveteau

In this thesis work, we propose to exploit an innovative micro/nano-fabrication process, based on controlled fluid instabilities of a thin viscous film of chalcogenide glass. Amorphous selenium and arsenic triselenide were used in this thesis work, and com ...

EPFL2024

Emergent nonlinear dynamics in photonic lattices

Aleksandr Tusnin

Since the discovery of dissipative Kerr solitons in optical microresonators, significant progress has been made in the understanding of the underlying physical principles from the fundamental side and generation of broadband coherent optical Kerr frequency ...

EPFL2024

Resonators with tailored optical path by cascaded-mode conversions

Ileana-Cristina Benea-Chelmus, Marco Piccardo

Optical resonators enable the generation, manipulation, and storage of electromagnetic waves. The physics underlying their operation is determined by the interference of electromagnetic waves, giving rise to the resonance spectrum. This mechanism causes th ...

Nature Portfolio2023