Publication

Device for Cell Culture on Deformable Surfaces

Hicham Majd
2008
Patents

Abstract

Device for the in vitro culture of cells comprising: a planar deformable substrate ( 3 ) with a culture surface ( 4 ), substrate deforming means for modifying the size of said culture surface ( 4 ), characterized by the fact that it furthermore comprises: substrate holding elements ( 5 ) which are located near the periphery of said culture surface ( 4 ), a frame ( 6,8 ) surrounding and directly or indirectly fixing said substrate holding elements ( 5 ), in such a way as to allow microscope viewing of the culture surface ( 4 ) and to avoid mechanical parts directly above or below the culture surface ( 4 ), said frame ( 6,8 ) being adapted to move said substrate holding elements ( 5 ) away from the center of said culture surface ( 4 ).

Official source

https://infoscience.epfl.ch/entities/publication/86d2f623-fcc3-4e72-ae1c-848e53bca082

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Hicham Majd
2008
Patents

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/86d2f623-fcc3-4e72-ae1c-848e53bca082

About this result

Related concepts (7)

Cell culture

Cell culture or tissue culture is the process by which cells are grown under controlled conditions, generally outside of their natural environment. The term "tissue culture" was coined by American pathologist Montrose Thomas Burrows. This technique is also called micropropagation. After the cells of interest have been isolated from living tissue, they can subsequently be maintained under carefully controlled conditions. They need to be kept at body temperature (37 °C) in an incubator.

Tissue culture

Tissue culture is the growth of tissues or cells in an artificial medium separate from the parent organism. This technique is also called micropropagation. This is typically facilitated via use of a liquid, semi-solid, or solid growth medium, such as broth or agar. Tissue culture commonly refers to the culture of animal cells and tissues, with the more specific term plant tissue culture being used for plants. The term "tissue culture" was coined by American pathologist Montrose Thomas Burrows.

Primary cell culture

Primary cell culture is the ex vivo culture of cells freshly obtained from a multicellular organism, as opposed to the culture of immortalized cell lines. In general, primary cell cultures are considered more representative of in vivo tissues than cell lines, and this is recognized legally in some countries such as the UK (Human Tissue Act 2004). However, primary cells require adequate substrate and nutrient conditions to thrive and after a certain number of divisions they acquire a senescent phenotype, leading to irreversible cell cycle arrest.

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