Publications related to Drosophila Serpin-28D regulates hemolymph phenoloxidase activity and adult pigmentation

First Advanced Bilayer Scaffolds for Tailored Skin Tissue Engineering Produced via Electrospinning and Melt Electrowriting

In vitro skin models are validated methods for screening cosmetics and pharmaceuticals, but still have limitations. The bilayer poly(epsilon-caprolactone) scaffold/membrane model described here overcomes some of these deficits by integrating a solution ele ...

Wiley-V C H Verlag Gmbh2024

PSGL-1 is an evolutionarily conserved antiviral restriction factor

Chao Jiang, Ying Liu

The arms race between viruses and their hosts shaped the evolutionary history and the genome composition of both parties. Restriction factors are the first-line antiviral effectors encoded by the host genomes and are often conserved through evolution to pr ...

AMER SOC MICROBIOLOGY2023

Enhancing Robustness of Adhesive Hydrogels through PEG-NHS Incorporation

Dominique Pioletti, François Gorostidi, Theofanis Stampoultzis, Yanheng Guo, Ece Uslu, Vijay Kumar Rana

Tissue wounds are a significant challenge for the healthcare system, affecting millions globally. Current methods like suturing and stapling have limitations as they inadequately cover the wound, fail to prevent fluid leakage, and increase the risk of infe ...

Amer Chemical Soc2023

Dataset for "Elastocapillary menisci mediate interaction of neighboring structures at the surface of a compliant solid"

John Martin Kolinski

This dataset supports the publication 'Elastocapillary menisci mediate interaction of neighboring structures at the surface of a compliant solid' by Lebo Molefe and John M. Kolinski, Physical Review E, (2023). The data are surface profiles of textured surf ...

Zenodo2023

Validating functional redundancy with mixed generative adversarial networks

Quoc Viet Hung Nguyen, Thành Tâm Nguyên, Trung-Dung Hoang, Thanh Trung Huynh

Data redundancy has been one of the most important problems in data-intensive applications such as data mining and machine learning. Removing data redundancy brings many benefits in efficient data updating, effective data storage, and error-free query proc ...

ELSEVIER2023

Shared metadata for data-centric materials science

Tristan Bereau, Gian-Marco Rignanese, Giovanni Pizzi, Ronald Earle Miller, Matthias Scheffler, Carsten Baldauf

The expansive production of data in materials science, their widespread sharing and repurposing requires educated support and stewardship. In order to ensure that this need helps rather than hinders scientific work, the implementation of the FAIR-data prin ...

Nature Portfolio2023

Toward a common standard for data and specimen provenance in life sciences

Marco Mattavelli, Anna Marsano

Open and practical exchange, dissemination, and reuse of specimens and data have become a fundamental requirement for life sciences research. The quality of the data obtained and thus the findings and knowledge derived is thus significantly influenced by t ...

WILEY2023

Screening for drivers of SARS-CoV-2 uptake

Christoph Merten, Alexis Louis Autour

Genetic and cellular drivers of the cellular uptake of SARS-CoV-2 can be screened at high throughput via droplet microfluidics and size-exclusion methods for the analysis of the formation of fusions between cells expressing the virus's spike protein and ce ...

Nature Portfolio2023

Data-driven Methods for Control: from Linear to Lifting

Yingzhao Lian

The progress towards intelligent systems and digitalization relies heavily on the use of automation technology. However, the growing diversity of control objects presents significant challenges for traditional control approaches, as they are highly depende ...

EPFL2023

Bacterial matrix metalloproteases and serine proteases contribute to the extra-host inactivation of enteroviruses in lake water

Virginie Bachmann, Tamar Kohn

Enteroviruses are ubiquitous contaminants of surface waters, yet their fate in presence of microbial congeners is poorly understood. In this work, we investigated the inactivation of Echovirus-11 (E11) and Coxsackievirus-A9 (CVA9) by bacteria isolated from ...

2022

Quantitative assessment of research data management practice - 2021

Chiara Gabella, Francesco Varrato, Eliane Ninfa Blumer

This survey aims to investigate research data management practices at EPFL and integrate their results into specific academic services. The previous two editions, in collaboration with TU Delft, Cambridge University and Illinois University, were carried ou ...

2022

Making the collective knowledge of chemistry open and machine actionable

Luc Patiny, Berend Smit, Kevin Maik Jablonka

Large amounts of data are generated in chemistry labs-nearly all instruments record data in a digital form, yet a considerable proportion is also captured non-digitally and reported in ways non-accessible to both humans and their computational agents. Chem ...

NATURE PORTFOLIO2022

Health data privacy through homomorphic encryption and distributed ledger computing: an ethical-legal qualitative expert assessment study

Marcello Ienca

Background: Increasingly, hospitals and research institutes are developing technical solutions for sharing patient data in a privacy preserving manner. Two of these technical solutions are homomorphic encryption and distributed ledger technology. Homomorph ...

BMC2022

The interplay between human genetic variation, chronic inflammation and persistent infection: relevance for cardiovascular morbidity

Flavia Aurelia Shoko Hodel

Contemporary genomic approaches allow us to seek answers to biological questions that were previously out of reach. Genome-wide association studies (GWAS) have identified numerous genetic polymorphisms associated with human diseases, providing new insight ...

EPFL2022

Rethinking student-teacher relationships in higher education: a multidimensional approach

Roland John Tormey

Student-teacher relationships play an important role in both teacher and student experiences in higher education and have been found to be linked to learning, classroom management, and to student absenteeism. Although historically conceptualised in terms o ...

2021

Data mining in the context of urban metabolism: A case study of Geneva and Lausanne, Switzerland

Claudia Rebeca Binder Signer, Nicole Sophie Wiedmann, Aristide Henri Roger Athanassiadis

The highest share of the global population lives in cities. The current configuration of the latter requires considerable amounts of resource flows causing the degradation of local and global ecosystems. To face the complexity of these challenges, scientis ...

IOP PUBLISHING LTD2021

Data Management Plans: the Importance of Data Management in the BIG-MAP Project[**]

Nicola Marzari, Giovanni Pizzi, Ivano Eligio Castelli, Martin Uhrin

Open access to research data is increasingly important for accelerating research. Grant authorities therefore request detailed plans for how data is managed in the projects they finance. We have recently developed such a plan for the EU H2020 BIG-MAP proje ...

WILEY-V C H VERLAG GMBH2021

A medical system and method using a pair of gloves equipped with physiological sensors

David Atienza Alonso

A medical system comprising a first wearable device configured to be worn by a first hand of a user, a second wearable device configured to be worn by a second hand of the user, a first sensor device arranged on the first wearable device, the first sensor ...

2021

Genetic, metabolic, and molecular insights into the diverse outcomes of diet-induced obesity in mouse

Alexis Maximilien Bachmann

Overweight and obesity are increasingly common public health issues worldwide, leading to a wide range of diseases from metabolic syndrome to steatohepatitis and cardiovascular diseases. While the increase in the prevalence of obesity is partly attributabl ...

EPFL2021

Spectroscopic and Electrokinetic Evidence for a Bifunctional Mechanism of the Oxygen Evolution Reaction**

Xile Hu, Lichen Bai, Seunghwa Lee

A bifunctional oxygen evolution reaction (OER) mechanism, in which the energetically demanding step of the attack of hydroxide on a metal oxo unit is facilitated by a hydrogen atom transfer to a second site, has the potential to circumvent the scaling rela ...

Wiley-VCH Verlag GmbH2021